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O61379

- TPM_PANST

UniProt

O61379 - TPM_PANST

Protein

Tropomyosin

Gene
N/A
Organism
Panulirus stimpsoni (Chinese spiny lobster)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (01 Aug 1998)
      Previous versions | rss
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    Functioni

    Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Tropomyosin
    Alternative name(s):
    Allergen Pan s I
    Allergen: Pan s 1
    OrganismiPanulirus stimpsoni (Chinese spiny lobster)
    Taxonomic identifieri71578 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataAchelataPalinuroideaPalinuridaePanulirus

    Pathology & Biotechi

    Allergenic propertiesi

    Causes an allergic reaction in human.

    Keywords - Diseasei

    Allergen

    Protein family/group databases

    Allergomei3396. Pan s 1.0101.
    500. Pan s 1.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 274274TropomyosinPRO_0000205676Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliO61379.
    SMRiO61379. Positions 1-273.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili1 – 274274By similarityAdd
    BLAST

    Domaini

    The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.

    Sequence similaritiesi

    Belongs to the tropomyosin family.Curated

    Keywords - Domaini

    Coiled coil, Repeat

    Family and domain databases

    InterProiIPR000533. Tropomyosin.
    [Graphical view]
    PfamiPF00261. Tropomyosin. 1 hit.
    [Graphical view]
    PRINTSiPR00194. TROPOMYOSIN.
    PROSITEiPS00326. TROPOMYOSIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O61379-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLEKDNAMD RADTLEQQNK EANIRAEKAE EEVHNLQKRM QQLENDLDQV    50
    QESLLKANTQ LEEKDKALSN AEGEVAALNR RIQLLEEDLE RSEERLNTAT 100
    TKLAEASQAA DESERMRKVL ENRSLSDEER MDALENQLKE ARFLAEEADR 150
    KYDEVARKLA MVEADLERAE ERAETGESKF VELEEELRVV GNNLKSLEVS 200
    EEKANQREEA YKEQIKTLTN KLKAAEARAE FAERSVQKLQ KEVDRLEDEL 250
    VNEKEKYKSI TDELDQTFSE LSGY 274
    Length:274
    Mass (Da):31,739
    Last modified:August 1, 1998 - v1
    Checksum:i886FACBE8CF1E81E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF030063 mRNA. Translation: AAC38996.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF030063 mRNA. Translation: AAC38996.1 .

    3D structure databases

    ProteinModelPortali O61379.
    SMRi O61379. Positions 1-273.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 3396. Pan s 1.0101.
    500. Pan s 1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR000533. Tropomyosin.
    [Graphical view ]
    Pfami PF00261. Tropomyosin. 1 hit.
    [Graphical view ]
    PRINTSi PR00194. TROPOMYOSIN.
    PROSITEi PS00326. TROPOMYOSIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular identification of the lobster muscle protein tropomyosin as a seafood allergen."
      Leung P.S.C., Chen Y.C., Mykles D.L., Chow W.K., Li C.P., Chu K.H.
      Mol. Mar. Biol. Biotechnol. 7:12-20(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Skeletal muscle.

    Entry informationi

    Entry nameiTPM_PANST
    AccessioniPrimary (citable) accession number: O61379
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 2001
    Last sequence update: August 1, 1998
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. Allergens
      Nomenclature of allergens and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3