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O61379

- TPM_PANST

UniProt

O61379 - TPM_PANST

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Protein

Tropomyosin

Gene
N/A
Organism
Panulirus stimpsoni (Chinese spiny lobster)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.

Names & Taxonomyi

Protein namesi
Recommended name:
Tropomyosin
Alternative name(s):
Allergen Pan s I
Allergen: Pan s 1
OrganismiPanulirus stimpsoni (Chinese spiny lobster)
Taxonomic identifieri71578 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataAchelataPalinuroideaPalinuridaePanulirus

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3396. Pan s 1.0101.
500. Pan s 1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 274274TropomyosinPRO_0000205676Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliO61379.
SMRiO61379. Positions 1-273.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili1 – 274274By similarityAdd
BLAST

Domaini

The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.

Sequence similaritiesi

Belongs to the tropomyosin family.Curated

Keywords - Domaini

Coiled coil, Repeat

Family and domain databases

InterProiIPR000533. Tropomyosin.
[Graphical view]
PfamiPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSiPR00194. TROPOMYOSIN.
PROSITEiPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O61379-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKLEKDNAMD RADTLEQQNK EANIRAEKAE EEVHNLQKRM QQLENDLDQV
60 70 80 90 100
QESLLKANTQ LEEKDKALSN AEGEVAALNR RIQLLEEDLE RSEERLNTAT
110 120 130 140 150
TKLAEASQAA DESERMRKVL ENRSLSDEER MDALENQLKE ARFLAEEADR
160 170 180 190 200
KYDEVARKLA MVEADLERAE ERAETGESKF VELEEELRVV GNNLKSLEVS
210 220 230 240 250
EEKANQREEA YKEQIKTLTN KLKAAEARAE FAERSVQKLQ KEVDRLEDEL
260 270
VNEKEKYKSI TDELDQTFSE LSGY
Length:274
Mass (Da):31,739
Last modified:August 1, 1998 - v1
Checksum:i886FACBE8CF1E81E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF030063 mRNA. Translation: AAC38996.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF030063 mRNA. Translation: AAC38996.1 .

3D structure databases

ProteinModelPortali O61379.
SMRi O61379. Positions 1-273.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

Allergomei 3396. Pan s 1.0101.
500. Pan s 1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR000533. Tropomyosin.
[Graphical view ]
Pfami PF00261. Tropomyosin. 1 hit.
[Graphical view ]
PRINTSi PR00194. TROPOMYOSIN.
PROSITEi PS00326. TROPOMYOSIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular identification of the lobster muscle protein tropomyosin as a seafood allergen."
    Leung P.S.C., Chen Y.C., Mykles D.L., Chow W.K., Li C.P., Chu K.H.
    Mol. Mar. Biol. Biotechnol. 7:12-20(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Skeletal muscle.

Entry informationi

Entry nameiTPM_PANST
AccessioniPrimary (citable) accession number: O61379
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: August 1, 1998
Last modified: October 1, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3