Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Tropomyosin

Gene
N/A
Organism
Panulirus stimpsoni (Chinese spiny lobster)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.

Names & Taxonomyi

Protein namesi
Recommended name:
Tropomyosin
Alternative name(s):
Allergen Pan s I
Allergen: Pan s 1
OrganismiPanulirus stimpsoni (Chinese spiny lobster)
Taxonomic identifieri71578 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataAchelataPalinuroideaPalinuridaePanulirus

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3396. Pan s 1.0101.
500. Pan s 1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002056761 – 274TropomyosinAdd BLAST274

Proteomic databases

PRIDEiO61379.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliO61379.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 274By similarityAdd BLAST274

Domaini

The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.

Sequence similaritiesi

Belongs to the tropomyosin family.Curated

Keywords - Domaini

Coiled coil, Repeat

Family and domain databases

InterProiIPR000533. Tropomyosin.
[Graphical view]
PfamiPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSiPR00194. TROPOMYOSIN.
PROSITEiPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O61379-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLEKDNAMD RADTLEQQNK EANIRAEKAE EEVHNLQKRM QQLENDLDQV
60 70 80 90 100
QESLLKANTQ LEEKDKALSN AEGEVAALNR RIQLLEEDLE RSEERLNTAT
110 120 130 140 150
TKLAEASQAA DESERMRKVL ENRSLSDEER MDALENQLKE ARFLAEEADR
160 170 180 190 200
KYDEVARKLA MVEADLERAE ERAETGESKF VELEEELRVV GNNLKSLEVS
210 220 230 240 250
EEKANQREEA YKEQIKTLTN KLKAAEARAE FAERSVQKLQ KEVDRLEDEL
260 270
VNEKEKYKSI TDELDQTFSE LSGY
Length:274
Mass (Da):31,739
Last modified:August 1, 1998 - v1
Checksum:i886FACBE8CF1E81E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030063 mRNA. Translation: AAC38996.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030063 mRNA. Translation: AAC38996.1.

3D structure databases

ProteinModelPortaliO61379.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3396. Pan s 1.0101.
500. Pan s 1.

Proteomic databases

PRIDEiO61379.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000533. Tropomyosin.
[Graphical view]
PfamiPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSiPR00194. TROPOMYOSIN.
PROSITEiPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTPM_PANST
AccessioniPrimary (citable) accession number: O61379
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: August 1, 1998
Last modified: October 5, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.