Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Anion exchange protein

Gene
N/A
Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Ion transportUniRule annotation, Transport

Enzyme and pathway databases

ReactomeiR-CEL-425381. Bicarbonate transporters.

Names & Taxonomyi

Protein namesi
Recommended name:
Anion exchange proteinUniRule annotation
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei429 – 45022HelicalUniRule annotationAdd
BLAST
Transmembranei471 – 49424HelicalUniRule annotationAdd
BLAST
Transmembranei514 – 53926HelicalUniRule annotationAdd
BLAST
Transmembranei546 – 56419HelicalUniRule annotationAdd
BLAST
Transmembranei648 – 66518HelicalUniRule annotationAdd
BLAST
Transmembranei685 – 70319HelicalUniRule annotationAdd
BLAST
Transmembranei733 – 75220HelicalUniRule annotationAdd
BLAST
Transmembranei773 – 79927HelicalUniRule annotationAdd
BLAST
Transmembranei833 – 85220HelicalUniRule annotationAdd
BLAST
Transmembranei859 – 87820HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiO61304.

Expressioni

Gene expression databases

ExpressionAtlasiO61304. baseline.

Structurei

3D structure databases

ProteinModelPortaliO61304.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini67 – 345279Band_3_cytoInterPro annotationAdd
BLAST
Domaini395 – 910516HCO3_cotranspInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the anion exchanger (TC 2.A.31) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

HOGENOMiHOG000280684.

Family and domain databases

Gene3Di3.40.1100.10. 1 hit.
InterProiIPR013769. Band3_cytoplasmic_dom.
IPR011531. HCO3_transpt_C.
IPR003020. HCO3_transpt_euk.
IPR003024. Na/HCO3_transpt.
IPR016152. PTrfase/Anion_transptr.
[Graphical view]
PANTHERiPTHR11453. PTHR11453. 2 hits.
PfamiPF07565. Band_3_cyto. 1 hit.
PF00955. HCO3_cotransp. 1 hit.
[Graphical view]
PRINTSiPR01231. HCO3TRNSPORT.
PR01232. NAHCO3TRSPRT.
SUPFAMiSSF55804. SSF55804. 1 hit.
TIGRFAMsiTIGR00834. ae. 1 hit.

Sequencei

Sequence statusi: Complete.

O61304-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHSVRRRMS KARRESQSIE LSSLAPGTRV MFLLKEKENT PALFTEMGEL
60 70 80 90 100
NNEEWRETAR WVKFEEDVEQ GGNRWSKPHV ATLSLHSLFQ LRSCIMNGHF
110 120 130 140 150
MNDLAETDIP SIFNAVIENL EKSGDLPSEN REELREILLR KHVHQYEQAK
160 170 180 190 200
KNGAGGEKGG FLSTVRSISD IGKSFSHGKN LSKIEEKPEG PVTSQTAGAP
210 220 230 240 250
SGSSNQLTLP TVESVPKDIS SEESSKGNLH FLKKLPAGVE ASNVLIGEVD
260 270 280 290 300
FLTRHICCFI RLKNANQLGD LTEVPVPTRF IFLLLGPTGH GQQYREIGRA
310 320 330 340 350
IATLMADEIF HDVAYGARDV DDLLDGIDEF LDQVTVLPPG EWDPNIRIEP
360 370 380 390 400
PSKLPSQEKR KQIGQELLVE PSSHKHVKKV VEEEEIHSHG DDPALKRTGK
410 420 430 440 450
LFGGLILDIK RKAPHFVSDF TDAFNLQCLA SICFMYFGLL APIVTFGGLL
460 470 480 490 500
EEATHQRMAA MENLFGGALW GVIYHFFAGQ PLTIVGSTGP VLVFETIVFD
510 520 530 540 550
FCHRLGMVYL SFRFWVHVWT AVIIFLMVVT DASALVSFIT RFTEESFATL
560 570 580 590 600
IAVIFIYEAI MKLVKIKGQL DMINYSRDFV EGGFCSCVPP IGKPSVSPDH
610 620 630 640 650
ARLVIKSTGL PIAFNDTFID YTAANLTDCR TIGGSFDGTT CFPLYDKLLM
660 670 680 690 700
SILLTVGTFF LATTLKKMRN SCYFPSSVRQ LLSDFAVMIA IASMTFVDIF
710 720 730 740 750
VGVNTPKLNV PSTFRPTWEG RGWFIPPFDA NEWWTAPLAI LPALLACILI
760 770 780 790 800
FMDQQITTVI VNRKENKLKK GCGYHLDLLV LSVSILMVGF LGLPIYVAAT
810 820 830 840 850
VLSINHINSL KVESECKAPG EVAQFVGVRE QRVTGIVTFL IIGLSVLATN
860 870 880 890 900
ILGRIPMPVL YGVFLYMGIS ALGGIQLFDR TLLLFMPMKY QPDTIYIRHV
910 920 930 940 950
PIRKIHLFTA FQIGCLALLW VIKSIKSTSI LFPIMLVVMV AIRKMMEKAF
960 970 980 990 1000
TTTDLKYLDD PMPDFHLRKK EDAKRRQSEG EAVEIEFDNE NQATTHAVKT
1010 1020 1030 1040 1050
EAHLHIPMAS GNVIKIPLAA IQEPSHSINL TKEVNNSGMW KHITSVDSKN
1060 1070 1080 1090 1100
SLVRDVPASS DPTSSRDAPI EQPEDDDDPI MIKVIRPSPH TSTSNLTTEN
1110
TPLLKDEEPP KTNPDEPKV
Length:1,119
Mass (Da):124,703
Last modified:August 1, 1998 - v1
Checksum:i9CA9A9C0A1BC48DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF004926 mRNA. Translation: AAC16758.1.
PIRiT37460.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF004926 mRNA. Translation: AAC16758.1.
PIRiT37460.

3D structure databases

ProteinModelPortaliO61304.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiO61304.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000280684.

Enzyme and pathway databases

ReactomeiR-CEL-425381. Bicarbonate transporters.

Gene expression databases

ExpressionAtlasiO61304. baseline.

Family and domain databases

Gene3Di3.40.1100.10. 1 hit.
InterProiIPR013769. Band3_cytoplasmic_dom.
IPR011531. HCO3_transpt_C.
IPR003020. HCO3_transpt_euk.
IPR003024. Na/HCO3_transpt.
IPR016152. PTrfase/Anion_transptr.
[Graphical view]
PANTHERiPTHR11453. PTHR11453. 2 hits.
PfamiPF07565. Band_3_cyto. 1 hit.
PF00955. HCO3_cotransp. 1 hit.
[Graphical view]
PRINTSiPR01231. HCO3TRNSPORT.
PR01232. NAHCO3TRSPRT.
SUPFAMiSSF55804. SSF55804. 1 hit.
TIGRFAMsiTIGR00834. ae. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Entry to "formula tunnel" revealed by SLC4A4 human mutation and structural model."
    Chang M.H., Dipiero J., Sonnichsen F.D., Romero M.F.
    J. Biol. Chem. 283:18402-18410(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO61304_CAEEL
AccessioniPrimary (citable) accession number: O61304
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: June 8, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.