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Protein
Submitted name:

Ligand-Gated ion Channel

Gene

lgc-30

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelUniRule annotation
Biological processIon transport, Transport

Enzyme and pathway databases

ReactomeiR-CEL-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-CEL-629587 Highly sodium permeable acetylcholine nicotinic receptors

Names & Taxonomyi

Protein namesi
Submitted name:
Ligand-Gated ion ChannelImported
Gene namesi
Name:lgc-30Imported
ORF Names:CELE_F58H7.3Imported, F58H7.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiF58H7.3 ; CE41140 ; WBGene00019069 ; lgc-30

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei274 – 299HelicalSequence analysisAdd BLAST26
Transmembranei311 – 332HelicalSequence analysisAdd BLAST22
Transmembranei352 – 374HelicalSequence analysisAdd BLAST23
Transmembranei506 – 524HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500415937018 – 529Sequence analysisAdd BLAST512

Proteomic databases

PaxDbiO61216

Expressioni

Gene expression databases

BgeeiWBGene00019069

Interactioni

Protein-protein interaction databases

STRINGi6239.F58H7.3

Structurei

3D structure databases

ProteinModelPortaliO61216
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 272Neur_chan_LBDInterPro annotationAdd BLAST199

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3645 Eukaryota
ENOG410XQGR LUCA
GeneTreeiENSGT00910000144023
HOGENOMiHOG000020122
InParanoidiO61216
OMAiVAMFMCH
OrthoDBiEOG091G06H0
PhylomeDBiO61216

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR018000 Neurotransmitter_ion_chnl_CS
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PRINTSiPR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit

Sequencei

Sequence statusi: Complete.

O61216-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLLSIFFMA TIWSCWGAQE SEGFIPKKLI KKPPAIDDTA FHRRRALDKE
60 70 80 90 100
DGGQVIADPD ADGDPHGRLA TWIRSHARHH IPLKHPHTRI DVFISAGLYQ
110 120 130 140 150
IVDLDQRNNL ATVSAYLDVH WNDDFIKWKP EIFGGIERIF VPIKWIWKPE
160 170 180 190 200
FYMYHSVYGR VPDYAPDASA ELHYNGLVRM FVSISSKSFC PINFKRFPFD
210 220 230 240 250
SQTCSFSCGS WAYQSNIVNL VAAKQEIALE DFYDNQEWLL TDARLFNGTT
260 270 280 290 300
RNVSAANESF SMVYMQLDLK RQSFYYVFNL VFPTTLVSLV AVIGFHAPIN
310 320 330 340 350
ATGRRESKFR LGIMTLLSMS VMLLMLVGEM KFAMESVPGQ RGSFSDVPLM
360 370 380 390 400
GIYYMTLICI VSIATCTSSI FVHLEKFALR NPSWQSVPWY IRWLAAKKLF
410 420 430 440 450
CCYVPKSFRY DKDAYSRNNN VQAISLHSTP DRNVAKNLIP KEINFTEVNQ
460 470 480 490 500
DAPLHDVLEG PSAEKTQKID LIVSLLREII HLKERIGASG QLAPYWDQII
510 520
SRCEKVSLSF YLFLITINVL MFLYPELWY
Length:529
Mass (Da):60,825
Last modified:September 11, 2007 - v3
Checksum:iA36FB739BD1CF460
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CCD67289.1
RefSeqiNP_500015.3, NM_067614.3
UniGeneiCel.12781

Genome annotation databases

EnsemblMetazoaiF58H7.3; F58H7.3; WBGene00019069
GeneIDi186551
KEGGicel:CELE_F58H7.3
UCSCiF58H7.3 c. elegans

Similar proteinsi

Entry informationi

Entry nameiO61216_CAEEL
AccessioniPrimary (citable) accession number: O61216
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: September 11, 2007
Last modified: May 23, 2018
This is version 146 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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