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Protein
Submitted name:

Apical merozoite antigen 1

Gene

AMA1

Organism
Plasmodium vivax
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Apical merozoite antigen 1Imported
Gene namesi
Name:AMA1Imported
OrganismiPlasmodium vivaxImported
Taxonomic identifieri5855 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Plasmodium)

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei485 – 50723HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi94 ↔ 247Combined sources
Disulfide bondi162 ↔ 192Combined sources
Disulfide bondi208 ↔ 220Combined sources
Disulfide bondi265 ↔ 363Combined sources
Disulfide bondi282 ↔ 354Combined sources
Disulfide bondi388 ↔ 444Combined sources
Disulfide bondi432 ↔ 449Combined sources
Disulfide bondi434 ↔ 451Combined sources

Expressioni

Keywords - Developmental stagei

MerozoiteImported

Interactioni

Protein-protein interaction databases

STRINGi5855.PVX_092275.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1W81X-ray2.01A43-487[»]
1W8KX-ray1.80A43-487[»]
ProteinModelPortaliO61130.
SMRiO61130. Positions 43-474.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO61130.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410JCXJ. Eukaryota.
ENOG410YK1C. LUCA.
HOGENOMiHOG000065866.

Family and domain databases

Gene3Di4.10.1010.10. 1 hit.
InterProiIPR003298. Apmem_Ag1.
IPR024056. Apmem_Ag1_domain.
[Graphical view]
PfamiPF02430. AMA-1. 1 hit.
[Graphical view]
PRINTSiPR01361. MEROZOITESA.
SMARTiSM00815. AMA-1. 1 hit.
[Graphical view]
SUPFAMiSSF82910. SSF82910. 2 hits.

Sequencei

Sequence statusi: Complete.

O61130-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKIYYIIFL SAQCLVHIGK CGRNQKPSRL TRSANNVLLE KGPTVERSTR
60 70 80 90 100
MSNPWKAFME KYDIERTHSS GVRVDLGEDA EVENAKYRIP AGRCPVFGKG
110 120 130 140 150
IVIENSDVSF LRPVATGDQK LKDGGFAFPN ANDHISPMTL ANLKERYKDN
160 170 180 190 200
VEMMKLNDIA LCRTHAASFV MAGDQNSSYR HPAVYDEKEK TCHMLYLSAQ
210 220 230 240 250
ENMGPRYCSP DAQNRDAVFC FKPDKNESFE NLVYLSKNVR NDWDKKCPRK
260 270 280 290 300
NLGNAKFGLW VDGNCEEIPY VKEVEAEDLR ECNRIVFGAS ASDQPTQYEE
310 320 330 340 350
EMTDYQKIQQ GFRQNNREMI KSAFLPVGAF NSDNFKSKGR GFNWANFDSV
360 370 380 390 400
KKKCYIFNTK PTCLINDKNF IATTALSHPQ EVDLEFPCSI YKDEIEREIK
410 420 430 440 450
KQSRNMNLYS VDGERIVLPR IFISNDKESI KCPCEPERIS NSTCNFYVCN
460 470 480 490 500
CVEKRAEIKE NNQVVIKEEF RDYYENGEEK SNKQMLLIII GITGGVCVVA
510 520 530 540 550
LASMAYFRKK ANNDKYDKMD QAEGYGKPTT RKDEMLDPEA SFWGEDKRAS
560
HTTPVLMEKP YY
Length:562
Mass (Da):64,477
Last modified:August 1, 1998 - v1
Checksum:i51B441344AD807FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF063138 Genomic DNA. Translation: AAC16731.1.

Genome annotation databases

EnsemblProtistsiPVX_092275; PVX_092275; PVX_092275.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF063138 Genomic DNA. Translation: AAC16731.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1W81X-ray2.01A43-487[»]
1W8KX-ray1.80A43-487[»]
ProteinModelPortaliO61130.
SMRiO61130. Positions 43-474.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5855.PVX_092275.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiPVX_092275; PVX_092275; PVX_092275.

Phylogenomic databases

eggNOGiENOG410JCXJ. Eukaryota.
ENOG410YK1C. LUCA.
HOGENOMiHOG000065866.

Miscellaneous databases

EvolutionaryTraceiO61130.

Family and domain databases

Gene3Di4.10.1010.10. 1 hit.
InterProiIPR003298. Apmem_Ag1.
IPR024056. Apmem_Ag1_domain.
[Graphical view]
PfamiPF02430. AMA-1. 1 hit.
[Graphical view]
PRINTSiPR01361. MEROZOITESA.
SMARTiSM00815. AMA-1. 1 hit.
[Graphical view]
SUPFAMiSSF82910. SSF82910. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiO61130_PLAVI
AccessioniPrimary (citable) accession number: O61130
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: March 16, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.