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Protein
Submitted name:

Putative RAD51 protein

Gene

RAD51

Organism
Leishmania major
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • ATPase activity Source: GeneDB
  • ATP binding Source: UniProtKB-KW
  • DNA-dependent ATPase activity Source: GO_Central
  • double-stranded DNA binding Source: GeneDB
  • double-stranded DNA-dependent ATPase activity Source: GeneDB
  • four-way junction DNA binding Source: GO_Central
  • recombinase activity Source: GO_Central
  • single-stranded DNA binding Source: GeneDB
  • single-stranded DNA-dependent ATPase activity Source: GeneDB

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Putative RAD51 proteinImported
Submitted name:
Rad51 homologImported
Gene namesi
Name:RAD51Imported
ORF Names:LMJF_28_0550Imported
OrganismiLeishmania majorImported
Taxonomic identifieri5664 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania
Proteomesi
  • UP000000542 Componenti: Chromosome 28

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi5664.LmjF.28.0550.

Structurei

3D structure databases

ProteinModelPortaliO61127.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini135 – 306RECA_2InterPro annotationAdd BLAST172
Domaini314 – 377RECA_3InterPro annotationAdd BLAST64

Sequence similaritiesi

Belongs to the RecA family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1433. Eukaryota.
COG0468. LUCA.
HOGENOMiHOG000227426.
KOiK04482.
OMAiCQLPIDQ.

Family and domain databases

CDDicd01123. Rad51_DMC1_radA. 1 hit.
Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011941. DNA_recomb/repair_Rad51.
IPR013632. DNA_recomb/repair_Rad51_C.
IPR016467. DNA_recomb/repair_RecA-like.
IPR010995. DNA_repair_Rad51/TF_NusA_a-hlx.
IPR027417. P-loop_NTPase.
IPR033925. Rad51_DMC1_RadA.
IPR020588. RecA_ATP-bd.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PfamiPF08423. Rad51. 1 hit.
[Graphical view]
PIRSFiPIRSF005856. Rad51. 1 hit.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF47794. SSF47794. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02239. recomb_RAD51. 1 hit.
PROSITEiPS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O61127-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTRSKAKGR RGRPSARPSE EVEVVESQPQ EVLQNEEQEP QQQQQQQSTD
60 70 80 90 100
MAEPNASGFR VIQILENYGV ASSDIKKLME CGFYTVESAA YAPKKAILAV
110 120 130 140 150
KGISENKAEK IMAECAKLVP MGFTSAVAYH EARKEIIMVT TGSREVDKLL
160 170 180 190 200
GGGIETGSIT ELFGEFRTGK TQLCHTLCVT CQLPISQGGA EGMALYIDTE
210 220 230 240 250
GTFRPERLVA VAERYKLDPE DVLANVACAR AFNTDHQQQL LLQASAMMAE
260 270 280 290 300
NRFALIIVDS ATALYRTDYS GRNELAARQM HLGKFLRSLH NLAEEYGVAV
310 320 330 340 350
VVTNQVVANV DGSAQMFQAD SKKPIGGHIM AHASTTRLSL RKGRGEQRII
360 370
KVYDSPCLAE AEAIFGIYDD GVGDARD
Length:377
Mass (Da):41,286
Last modified:August 1, 1998 - v1
Checksum:i71DCB64335BD2915
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF062379 Genomic DNA. Translation: AAC16334.1.
FR796424 Genomic DNA. Translation: CAJ05032.1.
RefSeqiXP_001684333.1. XM_001684281.1.

Genome annotation databases

EnsemblProtistsiLmjF.28.0550:mRNA; LmjF.28.0550:pep; LmjF.28.0550.
GeneDBiLmjF.28.0550:pep.
GeneIDi5653261.
KEGGilma:LMJF_28_0550.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF062379 Genomic DNA. Translation: AAC16334.1.
FR796424 Genomic DNA. Translation: CAJ05032.1.
RefSeqiXP_001684333.1. XM_001684281.1.

3D structure databases

ProteinModelPortaliO61127.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5664.LmjF.28.0550.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiLmjF.28.0550:mRNA; LmjF.28.0550:pep; LmjF.28.0550.
GeneDBiLmjF.28.0550:pep.
GeneIDi5653261.
KEGGilma:LMJF_28_0550.

Phylogenomic databases

eggNOGiKOG1433. Eukaryota.
COG0468. LUCA.
HOGENOMiHOG000227426.
KOiK04482.
OMAiCQLPIDQ.

Family and domain databases

CDDicd01123. Rad51_DMC1_radA. 1 hit.
Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011941. DNA_recomb/repair_Rad51.
IPR013632. DNA_recomb/repair_Rad51_C.
IPR016467. DNA_recomb/repair_RecA-like.
IPR010995. DNA_repair_Rad51/TF_NusA_a-hlx.
IPR027417. P-loop_NTPase.
IPR033925. Rad51_DMC1_RadA.
IPR020588. RecA_ATP-bd.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PfamiPF08423. Rad51. 1 hit.
[Graphical view]
PIRSFiPIRSF005856. Rad51. 1 hit.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF47794. SSF47794. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02239. recomb_RAD51. 1 hit.
PROSITEiPS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO61127_LEIMA
AccessioniPrimary (citable) accession number: O61127
Secondary accession number(s): Q4Q8L5
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: November 30, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.