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Protein
Submitted name:

Sialidase homolog

Gene

P85.1

Organism
Trypanosoma cruzi
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Protein family/group databases

CAZyiGH33. Glycoside Hydrolase Family 33.

Names & Taxonomyi

Protein namesi
Submitted name:
Sialidase homologImported
Gene namesi
Name:P85.1Imported
OrganismiTrypanosoma cruziImported
Taxonomic identifieri5693 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaSchizotrypanum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2626Sequence analysisAdd
BLAST
Chaini27 – 790764Sequence analysisPRO_5004159358Add
BLAST

Proteomic databases

PaxDbiO61081.

Structurei

3D structure databases

ProteinModelPortaliO61081.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini62 – 393332SialidasesInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view]
PfamiPF13859. BNR_3. 1 hit.
[Graphical view]
PRINTSiPR01803. TCSIALIDASE.
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

O61081-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRHLFCTAV LLIVVMICCG CGAAHAEQAG ATVDPFTGTT PISFANWKGF
60 70 80 90 100
NEARRKITSL RAPGLVKVGE DVFAVAEAQC GEENGAGSCA GIVSKHLNIS
110 120 130 140 150
GDPMDISTSD ISLFCMQLGD TAANNFGTTE VLRPTTLVFG NSVYMLLGNQ
160 170 180 190 200
SHTKTQFQGE NERGLLLVKG TVANEGGNNK KLLWNEAHVV KPEPRGESHS
210 220 230 240 250
LTELIGGGGS GAVMRDGTLV FPMQAKGNDG QSVLLSMSFT PSKNKWEFSS
260 270 280 290 300
EATGKGCRDP SIVEWGENEG DERPFMMARC AGGYYDVYKS TSHGVSWYDL
310 320 330 340 350
GEPINRVWGN SRDRAGDGVK SGFTTATIEE KEVMLITAPV YPKEENEGVK
360 370 380 390 400
GRLHLWVTDN ARVHDVGPIS REDDDSAASS LVKSKDELVL LYEKRNADRA
410 420 430 440 450
YSLVAMRLTE QLKRIKEVVK TWKEMDNALK VPTEGLVGFL SSTLDGTAWK
460 470 480 490 500
DEYLGVNATV RGGVTSTESG VTLKGSEAKW PVGDMGQTVP YYFTNNKFTL
510 520 530 540 550
SATVSIHEVP KEGSIPLIGA RLNDKDSTVL FQLSYTSERN WNFTLHKKDF
560 570 580 590 600
LVKPSGDVGN WETNTAIRVT VQKDNDDEWF VYANGRKIYE TDEEEMAQDS
610 620 630 640 650
NADQFGPHRI SHFFFGAGNK EDEGSSPVTV ADVLLYNRIL YDDDLGNLNA
660 670 680 690 700
RTVPIRHPAA EELHTAVKVT TTGEEKQTAT QLTTSLADVE EAPIAQPTNS
710 720 730 740 750
QSVRVLAGSE SSAENVTDEL SPHTAAKSDT SVPETNHSAS DGSMGPEDRL
760 770 780 790
ALITDAKLIL HDLRGDSTAR VRVSCVLLLL LGLCALVAVL
Length:790
Mass (Da):85,724
Last modified:August 1, 1998 - v1
Checksum:i6EADC41ED999F9F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051695 mRNA. Translation: AAD13334.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051695 mRNA. Translation: AAD13334.1.

3D structure databases

ProteinModelPortaliO61081.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH33. Glycoside Hydrolase Family 33.

Proteomic databases

PaxDbiO61081.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view]
PfamiPF13859. BNR_3. 1 hit.
[Graphical view]
PRINTSiPR01803. TCSIALIDASE.
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Weston D.S., Van Voorhis W.C.
    Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CLImported.
  2. "Virulence in Trypanosoma cruzi infection correlates with the expression of a distinct family of sialidase superfamily genes."
    Weston D., Patel B., Van Voorhis W.C.
    Mol. Biochem. Parasitol. 98:105-116(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CLImported.

Entry informationi

Entry nameiO61081_TRYCR
AccessioniPrimary (citable) accession number: O61081
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: April 13, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.