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Protein
Submitted name:

Myosin IC heavy chain

Gene

MICHC

Organism
Acanthamoeba castellanii (Amoeba)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Motor protein, MyosinSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin IC heavy chainImported
Gene namesi
Name:MICHCImported
OrganismiAcanthamoeba castellanii (Amoeba)Imported
Taxonomic identifieri5755 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaDiscoseaLongamoebiaCentramoebidaAcanthamoebidaeAcanthamoeba

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliO61080.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 684Myosin motorInterPro annotationAdd BLAST678
Domaini722 – 910TH1 (class I myosin tail homology)InterPro annotationAdd BLAST189
Domaini994 – 1053SH3InterPro annotationAdd BLAST60

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.SAAS annotation

Keywords - Domaini

SH3 domainSAAS annotation

Family and domain databases

InterProiIPR001609. Myosin_head_motor_dom.
IPR010926. Myosin_TH1.
IPR027417. P-loop_NTPase.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00063. Myosin_head. 1 hit.
PF06017. Myosin_TH1. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
PR00452. SH3DOMAIN.
SMARTiSM00242. MYSc. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS51456. MYOSIN_MOTOR. 1 hit.
PS50002. SH3. 1 hit.
PS51757. TH1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O61080-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYTSKHGVD DMVMLTSISN DAINDNLKKR FAADLIYTYI GHVLISVNPY
60 70 80 90 100
KQINNLYTER TLKDYRGKYR YELPPHVYAL ADDMYRTMLS ESEDQCVIIS
110 120 130 140 150
GESGAGKTEA SKKIMQYIAA VSGATGDVMR VKDVILESNP LLEAFGNAKT
160 170 180 190 200
IRNNNSSRFG KYMEIQFDLK GDPVGGRISN YLLEKSRVVY QTNGERNFHI
210 220 230 240 250
FYQLLAGAPA DLRQEFGLQT PDYYFYLNQG KTYTVDGMDD NQEFQDTWNA
260 270 280 290 300
MKVIGFTAEE QHEIFRLVTA ILYLGNVQFV DDGKGGSTIA DRQVVEMLAY
310 320 330 340 350
LMRTEPVAVE QALLYRTITT GEQGRGRSSV YSCPQDPLGA IYSRDALSKA
360 370 380 390 400
LYSRMFDYII QRVNDAMYID DPEALTTGIL DFYGFEIFGK NGFEQLCINF
410 420 430 440 450
VNEKLQQIFI QLTLKAEQEE YGAEGIQWEN IDYFNNKICC DLIEEKRPPG
460 470 480 490 500
LMTILDDVCN FPKGTDDKFR EKLLGAFPTH AHLAATSQPD EFVIKHYAGD
510 520 530 540 550
VVYNVDGFCD KNKDLLFKDL IGLAECTSST FFAGLFPEAK EVATSKKKPT
560 570 580 590 600
TAGFKIKESI NILVATLSKC TPHYIRCIKP NEKKAANDFN NSLVLHQVKY
610 620 630 640 650
LGLLENVRIR RAGYAYRQVY DKFFYRYRVV CPKTWSGWNG DMVSGAEAIL
660 670 680 690 700
NHVGMSLGKE YQKGKTKIFI RQPESVFSLE ELRDRTVFSY ANKIQRFLRK
710 720 730 740 750
TAMRKYYYEV KKGGNDALVN KKERRRLSLE RPFKTDYINY RQNFKLKDCI
760 770 780 790 800
GDKGTEKVLF ADLCNNLDKS FWGSKVERRI MVLTSNAMFL VAIDPNKDKI
810 820 830 840 850
EKKVKPFLYV LKRRIDFNKI GSITLSPLQD NFMLISVNGE HSNLLECRRK
860 870 880 890 900
TELIGVLLKH NPSVRIQFAD TFNVTLKGGK TCVVKFIRDP QGGDGKVKGT
910 920 930 940 950
KVSVAPGLPP SSAPNIQAPQ ETSGGASFTV AEQSYKDQIL GAKGGGGGGG
960 970 980 990 1000
RGRGGPSPSG AVSPRPSPGG GGGGPSPFGG RPSPSGPPAA ASAPGPEQAR
1010 1020 1030 1040 1050
ALYDFAAENP DELTFNEGAV VTVINKSNPD WWEGELNGQR GVFPASYVEL
1060 1070 1080 1090 1100
IPRAAAPAPG PSGGPRPAPP GGKSGRAAPM GGPGPMRGRG GPAPGGPGRG
1110 1120 1130 1140 1150
GAPPPGAGRA GPPGGRGMPA PGGAAPRGRG APPPGAGGPP GGGRGGAPPP
1160 1170 1180
GGMRGRGGPG PAPPGGMARG GMMPPRGRAG PPPPGM
Length:1,186
Mass (Da):129,461
Last modified:August 1, 1998 - v1
Checksum:iE37AD44A685803A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051353 mRNA. Translation: AAC98089.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051353 mRNA. Translation: AAC98089.1.

3D structure databases

ProteinModelPortaliO61080.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR001609. Myosin_head_motor_dom.
IPR010926. Myosin_TH1.
IPR027417. P-loop_NTPase.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00063. Myosin_head. 1 hit.
PF06017. Myosin_TH1. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
PR00452. SH3DOMAIN.
SMARTiSM00242. MYSc. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS51456. MYOSIN_MOTOR. 1 hit.
PS50002. SH3. 1 hit.
PS51757. TH1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO61080_ACACA
AccessioniPrimary (citable) accession number: O61080
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: November 30, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.