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Protein
Submitted name:

Myosin IC heavy chain

Gene

MICHC

Organism
Acanthamoeba castellanii (Amoeba)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi101 – 108ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotationSAAS annotation, Motor protein, MyosinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin IC heavy chainImported
Gene namesi
Name:MICHCImported
OrganismiAcanthamoeba castellanii (Amoeba)Imported
Taxonomic identifieri5755 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaDiscoseaLongamoebiaCentramoebidaAcanthamoebidaeAcanthamoeba

Subcellular locationi

GO - Cellular componenti

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliO61080
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 684Myosin motorInterPro annotationAdd BLAST678
Domaini722 – 910TH1InterPro annotationAdd BLAST189
Domaini994 – 1053SH3InterPro annotationAdd BLAST60

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni560 – 582Actin-bindingPROSITE-ProRule annotationAdd BLAST23

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

SH3 domainPROSITE-ProRule annotationSAAS annotation

Family and domain databases

CDDicd01378 MYSc_Myo1, 1 hit
Gene3Di3.40.850.10, 3 hits
InterProiView protein in InterPro
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR010926 Myosin_TH1
IPR036072 MYSc_Myo1
IPR027417 P-loop_NTPase
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00063 Myosin_head, 1 hit
PF06017 Myosin_TH1, 1 hit
PF14604 SH3_9, 1 hit
PRINTSiPR00193 MYOSINHEAVY
PR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00242 MYSc, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51456 MYOSIN_MOTOR, 1 hit
PS50002 SH3, 1 hit
PS51757 TH1, 1 hit

Sequencei

Sequence statusi: Complete.

O61080-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYTSKHGVD DMVMLTSISN DAINDNLKKR FAADLIYTYI GHVLISVNPY
60 70 80 90 100
KQINNLYTER TLKDYRGKYR YELPPHVYAL ADDMYRTMLS ESEDQCVIIS
110 120 130 140 150
GESGAGKTEA SKKIMQYIAA VSGATGDVMR VKDVILESNP LLEAFGNAKT
160 170 180 190 200
IRNNNSSRFG KYMEIQFDLK GDPVGGRISN YLLEKSRVVY QTNGERNFHI
210 220 230 240 250
FYQLLAGAPA DLRQEFGLQT PDYYFYLNQG KTYTVDGMDD NQEFQDTWNA
260 270 280 290 300
MKVIGFTAEE QHEIFRLVTA ILYLGNVQFV DDGKGGSTIA DRQVVEMLAY
310 320 330 340 350
LMRTEPVAVE QALLYRTITT GEQGRGRSSV YSCPQDPLGA IYSRDALSKA
360 370 380 390 400
LYSRMFDYII QRVNDAMYID DPEALTTGIL DFYGFEIFGK NGFEQLCINF
410 420 430 440 450
VNEKLQQIFI QLTLKAEQEE YGAEGIQWEN IDYFNNKICC DLIEEKRPPG
460 470 480 490 500
LMTILDDVCN FPKGTDDKFR EKLLGAFPTH AHLAATSQPD EFVIKHYAGD
510 520 530 540 550
VVYNVDGFCD KNKDLLFKDL IGLAECTSST FFAGLFPEAK EVATSKKKPT
560 570 580 590 600
TAGFKIKESI NILVATLSKC TPHYIRCIKP NEKKAANDFN NSLVLHQVKY
610 620 630 640 650
LGLLENVRIR RAGYAYRQVY DKFFYRYRVV CPKTWSGWNG DMVSGAEAIL
660 670 680 690 700
NHVGMSLGKE YQKGKTKIFI RQPESVFSLE ELRDRTVFSY ANKIQRFLRK
710 720 730 740 750
TAMRKYYYEV KKGGNDALVN KKERRRLSLE RPFKTDYINY RQNFKLKDCI
760 770 780 790 800
GDKGTEKVLF ADLCNNLDKS FWGSKVERRI MVLTSNAMFL VAIDPNKDKI
810 820 830 840 850
EKKVKPFLYV LKRRIDFNKI GSITLSPLQD NFMLISVNGE HSNLLECRRK
860 870 880 890 900
TELIGVLLKH NPSVRIQFAD TFNVTLKGGK TCVVKFIRDP QGGDGKVKGT
910 920 930 940 950
KVSVAPGLPP SSAPNIQAPQ ETSGGASFTV AEQSYKDQIL GAKGGGGGGG
960 970 980 990 1000
RGRGGPSPSG AVSPRPSPGG GGGGPSPFGG RPSPSGPPAA ASAPGPEQAR
1010 1020 1030 1040 1050
ALYDFAAENP DELTFNEGAV VTVINKSNPD WWEGELNGQR GVFPASYVEL
1060 1070 1080 1090 1100
IPRAAAPAPG PSGGPRPAPP GGKSGRAAPM GGPGPMRGRG GPAPGGPGRG
1110 1120 1130 1140 1150
GAPPPGAGRA GPPGGRGMPA PGGAAPRGRG APPPGAGGPP GGGRGGAPPP
1160 1170 1180
GGMRGRGGPG PAPPGGMARG GMMPPRGRAG PPPPGM
Length:1,186
Mass (Da):129,461
Last modified:August 1, 1998 - v1
Checksum:iE37AD44A685803A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051353 mRNA Translation: AAC98089.1

Similar proteinsi

Entry informationi

Entry nameiO61080_ACACA
AccessioniPrimary (citable) accession number: O61080
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: May 23, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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