##gff-version 3
O60869	UniProtKB	Initiator methionine	1	1	.	.	.	Note=Removed;Ontology_term=ECO:0000269,ECO:0007744,ECO:0007744,ECO:0007744;evidence=ECO:0000269|Ref.7,ECO:0007744|PubMed:19413330,ECO:0007744|PubMed:22223895,ECO:0007744|PubMed:25944712;Dbxref=PMID:19413330,PMID:22223895,PMID:25944712	
O60869	UniProtKB	Chain	2	148	.	.	.	ID=PRO_0000149795;Note=Endothelial differentiation-related factor 1	
O60869	UniProtKB	Domain	81	135	.	.	.	Note=HTH cro/C1-type;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00257	
O60869	UniProtKB	DNA binding	92	111	.	.	.	Note=H-T-H motif;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00257	
O60869	UniProtKB	Region	33	66	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
O60869	UniProtKB	Region	37	113	.	.	.	Note=Interaction with NR5A2%2C PPARG and NR1H3;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12040021;Dbxref=PMID:12040021	
O60869	UniProtKB	Region	69	108	.	.	.	Note=Interaction with TBP and NR5A1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10567391;Dbxref=PMID:10567391	
O60869	UniProtKB	Motif	81	88	.	.	.	Note=IQ motif	
O60869	UniProtKB	Modified residue	2	2	.	.	.	Note=N-acetylalanine;Ontology_term=ECO:0000269,ECO:0007744,ECO:0007744,ECO:0007744;evidence=ECO:0000269|Ref.7,ECO:0007744|PubMed:19413330,ECO:0007744|PubMed:22223895,ECO:0007744|PubMed:25944712;Dbxref=PMID:19413330,PMID:22223895,PMID:25944712	
O60869	UniProtKB	Modified residue	4	4	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
O60869	UniProtKB	Modified residue	25	25	.	.	.	Note=N6-methyllysine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:24129315;Dbxref=PMID:24129315	
O60869	UniProtKB	Alternative sequence	129	148	.	.	.	ID=VSP_054701;Note=In isoform 3. GLKLRGKDIGKPIEKGPRAK->DVGTRSARVLRAQ;Ontology_term=ECO:0000305;evidence=ECO:0000305	
O60869	UniProtKB	Alternative sequence	130	148	.	.	.	ID=VSP_013336;Note=In isoform 2. LKLRGKDIGKPIEKGPRAK->ECPSTLRRVR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:10567391;Dbxref=PMID:10567391	
O60869	UniProtKB	Mutagenesis	40	40	.	.	.	Note=Loss of interaction with CALM%3B when associated with D-58%3B D-91 and D-111. T->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10816571;Dbxref=PMID:10816571	
O60869	UniProtKB	Mutagenesis	58	58	.	.	.	Note=Loss of interaction with CALM%3B when associated with D-40%3B D-91 and D-111. T->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10816571;Dbxref=PMID:10816571	
O60869	UniProtKB	Mutagenesis	65	65	.	.	.	Note=No effect on CALM-binding. No effect%3B when associated with D-74. T->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15112053;Dbxref=PMID:15112053	
O60869	UniProtKB	Mutagenesis	74	74	.	.	.	Note=No effect on CALM-binding. No effect%3B when associated with D-65. T->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15112053;Dbxref=PMID:15112053	
O60869	UniProtKB	Mutagenesis	87	87	.	.	.	Note=No effect on CALM-binding. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15112053;Dbxref=PMID:15112053	
O60869	UniProtKB	Mutagenesis	87	87	.	.	.	Note=Loss of interaction with CALM and higher affinity for TBP. Same effect%3B when associated with D-65 and D-74. S->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15112053;Dbxref=PMID:15112053	
O60869	UniProtKB	Mutagenesis	91	91	.	.	.	Note=No effect on CALM-binding. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10816571;Dbxref=PMID:10816571	
O60869	UniProtKB	Mutagenesis	91	91	.	.	.	Note=Partial loss of interaction with CALM. Complete loss of interaction%3B when associated with D-40%3B D-58 and D-111. T->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10816571;Dbxref=PMID:10816571	
O60869	UniProtKB	Mutagenesis	111	111	.	.	.	Note=Loss of interaction with CALM%3B when associated with D-40%3B D-58 and D-91. S->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10816571;Dbxref=PMID:10816571	
O60869	UniProtKB	Helix	25	32	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6ZVH	
O60869	UniProtKB	Helix	58	63	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6ZVH	
O60869	UniProtKB	Helix	75	86	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6ZVH	
O60869	UniProtKB	Turn	87	89	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6ZVH	
O60869	UniProtKB	Helix	92	98	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6ZVH	
O60869	UniProtKB	Helix	103	110	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6ZVH	
O60869	UniProtKB	Helix	118	128	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6ZVH	
O60869	UniProtKB	Turn	135	138	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1X57	
O60869	UniProtKB	Beta strand	140	143	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1X57