Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O60861

- GAS7_HUMAN

UniProt

O60861 - GAS7_HUMAN

Protein

Growth arrest-specific protein 7

Gene

GAS7

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 137 (01 Oct 2014)
      Sequence version 3 (16 Dec 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    May play a role in promoting maturation and morphological differentiation of cerebellar neurons.

    GO - Molecular functioni

    1. sequence-specific DNA binding transcription factor activity Source: ProtInc

    GO - Biological processi

    1. actin filament bundle assembly Source: Ensembl
    2. actin filament polymerization Source: Ensembl
    3. cell cycle arrest Source: ProtInc
    4. neuron projection morphogenesis Source: Ensembl
    5. regulation of cell shape Source: Ensembl
    6. regulation of transcription, DNA-templated Source: GOC

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Differentiation, Neurogenesis

    Enzyme and pathway databases

    SignaLinkiO60861.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Growth arrest-specific protein 7
    Short name:
    GAS-7
    Gene namesi
    Name:GAS7
    Synonyms:KIAA0394
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 17

    Organism-specific databases

    HGNCiHGNC:4169. GAS7.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. actin filament Source: Ensembl
    2. cytoplasm Source: UniProtKB-SubCell
    3. ruffle Source: Ensembl

    Keywords - Cellular componenti

    Cytoplasm

    Pathology & Biotechi

    Involvement in diseasei

    A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with KMT2A/MLL1.

    Keywords - Diseasei

    Proto-oncogene

    Organism-specific databases

    PharmGKBiPA28583.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 476476Growth arrest-specific protein 7PRO_0000076057Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei117 – 1171Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiO60861.
    PaxDbiO60861.
    PRIDEiO60861.

    PTM databases

    PhosphoSiteiO60861.

    Expressioni

    Gene expression databases

    ArrayExpressiO60861.
    BgeeiO60861.
    CleanExiHS_GAS7.
    GenevestigatoriO60861.

    Organism-specific databases

    HPAiHPA004838.

    Interactioni

    Protein-protein interaction databases

    BioGridi114094. 21 interactions.
    IntActiO60861. 12 interactions.
    MINTiMINT-1577125.
    STRINGi9606.ENSP00000322608.

    Structurei

    Secondary structure

    1
    476
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi5 – 95
    Beta strandi28 – 325
    Beta strandi40 – 434
    Beta strandi49 – 524
    Helixi54 – 563
    Beta strandi57 – 593
    Beta strandi84 – 874
    Beta strandi93 – 964
    Beta strandi98 – 1003
    Beta strandi103 – 1075

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2LX7NMR-A1-60[»]
    2YSHNMR-A79-111[»]
    ProteinModelPortaliO60861.
    SMRiO60861. Positions 1-131, 200-475.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiO60861.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 6262SH3PROSITE-ProRule annotationAdd
    BLAST
    Domaini77 – 11034WWPROSITE-ProRule annotationAdd
    BLAST
    Domaini196 – 28893FCHPROSITE-ProRule annotationAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili309 – 419111Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi67 – 704Poly-Pro

    Sequence similaritiesi

    Contains 1 FCH domain.PROSITE-ProRule annotation
    Contains 1 SH3 domain.PROSITE-ProRule annotation
    Contains 1 WW domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Coiled coil, SH3 domain

    Phylogenomic databases

    eggNOGiNOG271795.
    HOGENOMiHOG000294146.
    HOVERGENiHBG001320.
    InParanoidiO60861.
    OMAiHMSLRKP.
    OrthoDBiEOG7SN8CQ.
    PhylomeDBiO60861.
    TreeFamiTF328986.

    Family and domain databases

    InterProiIPR001060. FCH_dom.
    IPR001452. SH3_domain.
    IPR001202. WW_dom.
    [Graphical view]
    PfamiPF00611. FCH. 1 hit.
    PF14604. SH3_9. 1 hit.
    PF00397. WW. 1 hit.
    [Graphical view]
    SMARTiSM00055. FCH. 1 hit.
    SM00326. SH3. 1 hit.
    SM00456. WW. 1 hit.
    [Graphical view]
    SUPFAMiSSF50044. SSF50044. 1 hit.
    SSF51045. SSF51045. 1 hit.
    PROSITEiPS50133. FCH. 1 hit.
    PS50002. SH3. 1 hit.
    PS01159. WW_DOMAIN_1. 1 hit.
    PS50020. WW_DOMAIN_2. 1 hit.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 3 (identifier: O60861-3) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MSGARCRTLY PFSGERHGQG LRFAAGELIT LLQVPDGGWW EGEKEDGLRG    50
    WFPASYVQLL EKPGMVPPPP GEESQTVILP PGWQSYLSPQ GRRYYVNTTT 100
    NETTWERPSS SPGIPASPGS HRSSLPPTVN GYHASGTPAH PPETAHMSVR 150
    KSTGDSQNLG SSSPSKKQSK ENTITINCVT FPHPDTMPEQ QLLKPTEWSY 200
    CDYFWADKKD PQGNGTVAGF ELLLQKQLKG KQMQKEMSEF IRERIKIEED 250
    YAKNLAKLSQ NSLASQEEGS LGEAWAQVKK SLADEAEVHL KFSAKLHSEV 300
    EKPLMNFREN FKKDMKKCDH HIADLRKQLA SRYASVEKAR KALTERQRDL 350
    EMKTQQLEIK LSNKTEEDIK KARRKSTQAG DDLMRCVDLY NQAQSKWFEE 400
    MVTTTLELER LEVERVEMIR QHLCQYTQLR HETDMFNQST VEPVDQLLRK 450
    VDPAKDRELW VREHKTGNIR PVDMEI 476
    Length:476
    Mass (Da):54,371
    Last modified:December 16, 2008 - v3
    Checksum:i57BFB99907652745
    GO
    Isoform 1 (identifier: O60861-1) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-64: Missing.

    Show »
    Length:412
    Mass (Da):47,266
    Checksum:iB65049D5F18254A7
    GO
    Isoform 2 (identifier: O60861-2) [UniParc]FASTAAdd to Basket

    Also known as: GAS7-CB

    The sequence of this isoform differs from the canonical sequence as follows:
         1-140: Missing.
         141-156: PPETAHMSVRKSTGDS → MSNMENSFDDVSCLSP

    Show »
    Length:336
    Mass (Da):39,206
    Checksum:iB57E482E417B5F39
    GO
    Isoform 4 (identifier: O60861-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-60: Missing.
         61-61: E → M

    Show »
    Length:416
    Mass (Da):47,680
    Checksum:i56CCB6E52CC680F5
    GO

    Sequence cautioni

    The sequence BAA23690.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti301 – 3011E → D in CAA12177. 1 PublicationCurated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 140140Missing in isoform 2. 2 PublicationsVSP_006802Add
    BLAST
    Alternative sequencei1 – 6464Missing in isoform 1. 3 PublicationsVSP_035988Add
    BLAST
    Alternative sequencei1 – 6060Missing in isoform 4. 2 PublicationsVSP_044294Add
    BLAST
    Alternative sequencei61 – 611E → M in isoform 4. 2 PublicationsVSP_044295
    Alternative sequencei141 – 15616PPETA…STGDS → MSNMENSFDDVSCLSP in isoform 2. 2 PublicationsVSP_006803Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ224876 mRNA. Translation: CAA12177.1.
    AB007854 mRNA. Translation: BAA23690.2. Different initiation.
    AY327406 mRNA. Translation: AAP92798.1.
    BT006891 mRNA. Translation: AAP35537.1.
    AK292987 mRNA. Translation: BAF85676.1.
    AK315162 mRNA. Translation: BAG37606.1.
    AC000003 Genomic DNA. No translation available.
    AC005747 Genomic DNA. No translation available.
    AC026591 Genomic DNA. No translation available.
    AC083783 Genomic DNA. No translation available.
    AC107938 Genomic DNA. No translation available.
    CH471108 Genomic DNA. Translation: EAW90013.1.
    CH471108 Genomic DNA. Translation: EAW90011.1.
    CH471108 Genomic DNA. Translation: EAW90012.1.
    BC001152 mRNA. Translation: AAH01152.1.
    BC006454 mRNA. Translation: AAH06454.2.
    AF231998 mRNA. Translation: AAG26332.2. Sequence problems.
    CCDSiCCDS11152.1. [O60861-3]
    CCDS42263.1. [O60861-4]
    CCDS45611.1. [O60861-2]
    CCDS58518.1. [O60861-1]
    RefSeqiNP_001124303.1. NM_001130831.1. [O60861-1]
    NP_003635.2. NM_003644.2. [O60861-2]
    NP_958836.1. NM_201432.1. [O60861-4]
    NP_958839.1. NM_201433.1. [O60861-3]
    XP_005256888.1. XM_005256831.2. [O60861-1]
    XP_005256889.1. XM_005256832.2. [O60861-1]
    UniGeneiHs.462214.

    Genome annotation databases

    EnsembliENST00000323816; ENSP00000322608; ENSG00000007237. [O60861-4]
    ENST00000432992; ENSP00000407552; ENSG00000007237. [O60861-3]
    ENST00000437099; ENSP00000410108; ENSG00000007237. [O60861-1]
    ENST00000542249; ENSP00000443265; ENSG00000007237. [O60861-1]
    ENST00000579158; ENSP00000463527; ENSG00000007237. [O60861-1]
    ENST00000580865; ENSP00000463873; ENSG00000007237. [O60861-2]
    ENST00000585266; ENSP00000464240; ENSG00000007237. [O60861-4]
    GeneIDi8522.
    KEGGihsa:8522.
    UCSCiuc002gmg.1. human. [O60861-3]
    uc002gmh.1. human. [O60861-2]
    uc002gmj.1. human. [O60861-4]

    Keywords - Coding sequence diversityi

    Alternative splicing, Chromosomal rearrangement

    Cross-referencesi

    Web resourcesi

    Atlas of Genetics and Cytogenetics in Oncology and Haematology

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ224876 mRNA. Translation: CAA12177.1 .
    AB007854 mRNA. Translation: BAA23690.2 . Different initiation.
    AY327406 mRNA. Translation: AAP92798.1 .
    BT006891 mRNA. Translation: AAP35537.1 .
    AK292987 mRNA. Translation: BAF85676.1 .
    AK315162 mRNA. Translation: BAG37606.1 .
    AC000003 Genomic DNA. No translation available.
    AC005747 Genomic DNA. No translation available.
    AC026591 Genomic DNA. No translation available.
    AC083783 Genomic DNA. No translation available.
    AC107938 Genomic DNA. No translation available.
    CH471108 Genomic DNA. Translation: EAW90013.1 .
    CH471108 Genomic DNA. Translation: EAW90011.1 .
    CH471108 Genomic DNA. Translation: EAW90012.1 .
    BC001152 mRNA. Translation: AAH01152.1 .
    BC006454 mRNA. Translation: AAH06454.2 .
    AF231998 mRNA. Translation: AAG26332.2 . Sequence problems.
    CCDSi CCDS11152.1. [O60861-3 ]
    CCDS42263.1. [O60861-4 ]
    CCDS45611.1. [O60861-2 ]
    CCDS58518.1. [O60861-1 ]
    RefSeqi NP_001124303.1. NM_001130831.1. [O60861-1 ]
    NP_003635.2. NM_003644.2. [O60861-2 ]
    NP_958836.1. NM_201432.1. [O60861-4 ]
    NP_958839.1. NM_201433.1. [O60861-3 ]
    XP_005256888.1. XM_005256831.2. [O60861-1 ]
    XP_005256889.1. XM_005256832.2. [O60861-1 ]
    UniGenei Hs.462214.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2LX7 NMR - A 1-60 [» ]
    2YSH NMR - A 79-111 [» ]
    ProteinModelPortali O60861.
    SMRi O60861. Positions 1-131, 200-475.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 114094. 21 interactions.
    IntActi O60861. 12 interactions.
    MINTi MINT-1577125.
    STRINGi 9606.ENSP00000322608.

    PTM databases

    PhosphoSitei O60861.

    Proteomic databases

    MaxQBi O60861.
    PaxDbi O60861.
    PRIDEi O60861.

    Protocols and materials databases

    DNASUi 8522.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000323816 ; ENSP00000322608 ; ENSG00000007237 . [O60861-4 ]
    ENST00000432992 ; ENSP00000407552 ; ENSG00000007237 . [O60861-3 ]
    ENST00000437099 ; ENSP00000410108 ; ENSG00000007237 . [O60861-1 ]
    ENST00000542249 ; ENSP00000443265 ; ENSG00000007237 . [O60861-1 ]
    ENST00000579158 ; ENSP00000463527 ; ENSG00000007237 . [O60861-1 ]
    ENST00000580865 ; ENSP00000463873 ; ENSG00000007237 . [O60861-2 ]
    ENST00000585266 ; ENSP00000464240 ; ENSG00000007237 . [O60861-4 ]
    GeneIDi 8522.
    KEGGi hsa:8522.
    UCSCi uc002gmg.1. human. [O60861-3 ]
    uc002gmh.1. human. [O60861-2 ]
    uc002gmj.1. human. [O60861-4 ]

    Organism-specific databases

    CTDi 8522.
    GeneCardsi GC17M009813.
    HGNCi HGNC:4169. GAS7.
    HPAi HPA004838.
    MIMi 603127. gene.
    neXtProti NX_O60861.
    PharmGKBi PA28583.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG271795.
    HOGENOMi HOG000294146.
    HOVERGENi HBG001320.
    InParanoidi O60861.
    OMAi HMSLRKP.
    OrthoDBi EOG7SN8CQ.
    PhylomeDBi O60861.
    TreeFami TF328986.

    Enzyme and pathway databases

    SignaLinki O60861.

    Miscellaneous databases

    ChiTaRSi GAS7. human.
    EvolutionaryTracei O60861.
    GeneWikii GAS7.
    GenomeRNAii 8522.
    NextBioi 31908.
    PROi O60861.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi O60861.
    Bgeei O60861.
    CleanExi HS_GAS7.
    Genevestigatori O60861.

    Family and domain databases

    InterProi IPR001060. FCH_dom.
    IPR001452. SH3_domain.
    IPR001202. WW_dom.
    [Graphical view ]
    Pfami PF00611. FCH. 1 hit.
    PF14604. SH3_9. 1 hit.
    PF00397. WW. 1 hit.
    [Graphical view ]
    SMARTi SM00055. FCH. 1 hit.
    SM00326. SH3. 1 hit.
    SM00456. WW. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50044. SSF50044. 1 hit.
    SSF51045. SSF51045. 1 hit.
    PROSITEi PS50133. FCH. 1 hit.
    PS50002. SH3. 1 hit.
    PS01159. WW_DOMAIN_1. 1 hit.
    PS50020. WW_DOMAIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Human gas7: conservation of a mammalian growth-arrest-specific gene."
      Chao C.C.-K., Kuo J.T., Ju Y.-T., Lin-Chao S.
      Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
      Tissue: Cerebellum.
    2. "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro."
      Ishikawa K., Nagase T., Nakajima D., Seki N., Ohira M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
      DNA Res. 4:307-313(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4).
      Tissue: Brain.
    3. Shan Y.X., Yu L.
      Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    4. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
      Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 4).
      Tissue: Thalamus and Trachea.
    6. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
      Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
      , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
      Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Eye and Skin.
    9. "Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors."
      Megonigal M.D., Cheung N.-K.V., Rappaport E.F., Nowell P.C., Wilson R.B., Jones D.H., Addya K., Leonard D.G.B., Kushner B.H., Williams T.M., Lange B.J., Felix C.A.
      Proc. Natl. Acad. Sci. U.S.A. 97:2814-2819(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA], CHROMOSOMAL TRANSLOCATION WITH KMT2A/MLL1.
    10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-117, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    11. "Solution structure of the WW domain from the human growth-arrest-specific protein 7, GAS-7."
      RIKEN structural genomics initiative (RSGI)
      Submitted (OCT-2007) to the PDB data bank
      Cited for: STRUCTURE BY NMR OF 79-111.

    Entry informationi

    Entry nameiGAS7_HUMAN
    AccessioniPrimary (citable) accession number: O60861
    Secondary accession number(s): A8KAC2
    , B2RCK9, O43144, Q53Y77, Q7Z571
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 11, 2001
    Last sequence update: December 16, 2008
    Last modified: October 1, 2014
    This is version 137 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 17
      Human chromosome 17: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3