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O60861

- GAS7_HUMAN

UniProt

O60861 - GAS7_HUMAN

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Protein
Growth arrest-specific protein 7
Gene
GAS7, KIAA0394
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

May play a role in promoting maturation and morphological differentiation of cerebellar neurons.

GO - Molecular functioni

  1. sequence-specific DNA binding transcription factor activity Source: ProtInc
Complete GO annotation...

GO - Biological processi

  1. actin filament bundle assembly Source: Ensembl
  2. actin filament polymerization Source: Ensembl
  3. cell cycle arrest Source: ProtInc
  4. neuron projection morphogenesis Source: Ensembl
  5. regulation of cell shape Source: Ensembl
  6. regulation of transcription, DNA-templated Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Differentiation, Neurogenesis

Enzyme and pathway databases

SignaLinkiO60861.

Names & Taxonomyi

Protein namesi
Recommended name:
Growth arrest-specific protein 7
Short name:
GAS-7
Gene namesi
Name:GAS7
Synonyms:KIAA0394
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:4169. GAS7.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. actin filament Source: Ensembl
  2. cytoplasm Source: UniProtKB-SubCell
  3. ruffle Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Involvement in diseasei

A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with KMT2A/MLL1.

Keywords - Diseasei

Proto-oncogene

Organism-specific databases

PharmGKBiPA28583.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 476476Growth arrest-specific protein 7
PRO_0000076057Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei117 – 1171Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO60861.
PaxDbiO60861.
PRIDEiO60861.

PTM databases

PhosphoSiteiO60861.

Expressioni

Gene expression databases

ArrayExpressiO60861.
BgeeiO60861.
CleanExiHS_GAS7.
GenevestigatoriO60861.

Organism-specific databases

HPAiHPA004838.

Interactioni

Protein-protein interaction databases

BioGridi114094. 21 interactions.
IntActiO60861. 12 interactions.
MINTiMINT-1577125.
STRINGi9606.ENSP00000322608.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi5 – 95
Beta strandi28 – 325
Beta strandi40 – 434
Beta strandi49 – 524
Helixi54 – 563
Beta strandi57 – 593
Beta strandi84 – 874
Beta strandi93 – 964
Beta strandi98 – 1003
Beta strandi103 – 1075

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2LX7NMR-A1-60[»]
2YSHNMR-A79-111[»]
ProteinModelPortaliO60861.
SMRiO60861. Positions 1-131, 200-475.

Miscellaneous databases

EvolutionaryTraceiO60861.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 6262SH3
Add
BLAST
Domaini77 – 11034WW
Add
BLAST
Domaini196 – 28893FCH
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili309 – 419111 Reviewed prediction
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi67 – 704Poly-Pro

Sequence similaritiesi

Contains 1 FCH domain.
Contains 1 SH3 domain.
Contains 1 WW domain.

Keywords - Domaini

Coiled coil, SH3 domain

Phylogenomic databases

eggNOGiNOG271795.
HOGENOMiHOG000294146.
HOVERGENiHBG001320.
InParanoidiO60861.
OMAiHMSLRKP.
OrthoDBiEOG7SN8CQ.
PhylomeDBiO60861.
TreeFamiTF328986.

Family and domain databases

InterProiIPR001060. FCH_dom.
IPR001452. SH3_domain.
IPR001202. WW_dom.
[Graphical view]
PfamiPF00611. FCH. 1 hit.
PF14604. SH3_9. 1 hit.
PF00397. WW. 1 hit.
[Graphical view]
SMARTiSM00055. FCH. 1 hit.
SM00326. SH3. 1 hit.
SM00456. WW. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF51045. SSF51045. 1 hit.
PROSITEiPS50133. FCH. 1 hit.
PS50002. SH3. 1 hit.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform 3 (identifier: O60861-3) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MSGARCRTLY PFSGERHGQG LRFAAGELIT LLQVPDGGWW EGEKEDGLRG    50
WFPASYVQLL EKPGMVPPPP GEESQTVILP PGWQSYLSPQ GRRYYVNTTT 100
NETTWERPSS SPGIPASPGS HRSSLPPTVN GYHASGTPAH PPETAHMSVR 150
KSTGDSQNLG SSSPSKKQSK ENTITINCVT FPHPDTMPEQ QLLKPTEWSY 200
CDYFWADKKD PQGNGTVAGF ELLLQKQLKG KQMQKEMSEF IRERIKIEED 250
YAKNLAKLSQ NSLASQEEGS LGEAWAQVKK SLADEAEVHL KFSAKLHSEV 300
EKPLMNFREN FKKDMKKCDH HIADLRKQLA SRYASVEKAR KALTERQRDL 350
EMKTQQLEIK LSNKTEEDIK KARRKSTQAG DDLMRCVDLY NQAQSKWFEE 400
MVTTTLELER LEVERVEMIR QHLCQYTQLR HETDMFNQST VEPVDQLLRK 450
VDPAKDRELW VREHKTGNIR PVDMEI 476
Length:476
Mass (Da):54,371
Last modified:December 16, 2008 - v3
Checksum:i57BFB99907652745
GO
Isoform 1 (identifier: O60861-1) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-64: Missing.

Show »
Length:412
Mass (Da):47,266
Checksum:iB65049D5F18254A7
GO
Isoform 2 (identifier: O60861-2) [UniParc]FASTAAdd to Basket

Also known as: GAS7-CB

The sequence of this isoform differs from the canonical sequence as follows:
     1-140: Missing.
     141-156: PPETAHMSVRKSTGDS → MSNMENSFDDVSCLSP

Show »
Length:336
Mass (Da):39,206
Checksum:iB57E482E417B5F39
GO
Isoform 4 (identifier: O60861-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-60: Missing.
     61-61: E → M

Show »
Length:416
Mass (Da):47,680
Checksum:i56CCB6E52CC680F5
GO

Sequence cautioni

The sequence BAA23690.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 140140Missing in isoform 2.
VSP_006802Add
BLAST
Alternative sequencei1 – 6464Missing in isoform 1.
VSP_035988Add
BLAST
Alternative sequencei1 – 6060Missing in isoform 4.
VSP_044294Add
BLAST
Alternative sequencei61 – 611E → M in isoform 4.
VSP_044295
Alternative sequencei141 – 15616PPETA…STGDS → MSNMENSFDDVSCLSP in isoform 2.
VSP_006803Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti301 – 3011E → D in CAA12177. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ224876 mRNA. Translation: CAA12177.1.
AB007854 mRNA. Translation: BAA23690.2. Different initiation.
AY327406 mRNA. Translation: AAP92798.1.
BT006891 mRNA. Translation: AAP35537.1.
AK292987 mRNA. Translation: BAF85676.1.
AK315162 mRNA. Translation: BAG37606.1.
AC000003 Genomic DNA. No translation available.
AC005747 Genomic DNA. No translation available.
AC026591 Genomic DNA. No translation available.
AC083783 Genomic DNA. No translation available.
AC107938 Genomic DNA. No translation available.
CH471108 Genomic DNA. Translation: EAW90013.1.
CH471108 Genomic DNA. Translation: EAW90011.1.
CH471108 Genomic DNA. Translation: EAW90012.1.
BC001152 mRNA. Translation: AAH01152.1.
BC006454 mRNA. Translation: AAH06454.2.
AF231998 mRNA. Translation: AAG26332.2. Sequence problems.
CCDSiCCDS11152.1. [O60861-3]
CCDS42263.1. [O60861-4]
CCDS45611.1. [O60861-2]
CCDS58518.1. [O60861-1]
RefSeqiNP_001124303.1. NM_001130831.1. [O60861-1]
NP_003635.2. NM_003644.2. [O60861-2]
NP_958836.1. NM_201432.1. [O60861-4]
NP_958839.1. NM_201433.1. [O60861-3]
XP_005256888.1. XM_005256831.2. [O60861-1]
XP_005256889.1. XM_005256832.2. [O60861-1]
UniGeneiHs.462214.

Genome annotation databases

EnsembliENST00000323816; ENSP00000322608; ENSG00000007237. [O60861-4]
ENST00000432992; ENSP00000407552; ENSG00000007237. [O60861-3]
ENST00000437099; ENSP00000410108; ENSG00000007237. [O60861-1]
ENST00000542249; ENSP00000443265; ENSG00000007237. [O60861-1]
ENST00000579158; ENSP00000463527; ENSG00000007237. [O60861-1]
ENST00000580865; ENSP00000463873; ENSG00000007237. [O60861-2]
ENST00000585266; ENSP00000464240; ENSG00000007237. [O60861-4]
GeneIDi8522.
KEGGihsa:8522.
UCSCiuc002gmg.1. human. [O60861-3]
uc002gmh.1. human. [O60861-2]
uc002gmj.1. human. [O60861-4]

Keywords - Coding sequence diversityi

Alternative splicing, Chromosomal rearrangement

Cross-referencesi

Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ224876 mRNA. Translation: CAA12177.1 .
AB007854 mRNA. Translation: BAA23690.2 . Different initiation.
AY327406 mRNA. Translation: AAP92798.1 .
BT006891 mRNA. Translation: AAP35537.1 .
AK292987 mRNA. Translation: BAF85676.1 .
AK315162 mRNA. Translation: BAG37606.1 .
AC000003 Genomic DNA. No translation available.
AC005747 Genomic DNA. No translation available.
AC026591 Genomic DNA. No translation available.
AC083783 Genomic DNA. No translation available.
AC107938 Genomic DNA. No translation available.
CH471108 Genomic DNA. Translation: EAW90013.1 .
CH471108 Genomic DNA. Translation: EAW90011.1 .
CH471108 Genomic DNA. Translation: EAW90012.1 .
BC001152 mRNA. Translation: AAH01152.1 .
BC006454 mRNA. Translation: AAH06454.2 .
AF231998 mRNA. Translation: AAG26332.2 . Sequence problems.
CCDSi CCDS11152.1. [O60861-3 ]
CCDS42263.1. [O60861-4 ]
CCDS45611.1. [O60861-2 ]
CCDS58518.1. [O60861-1 ]
RefSeqi NP_001124303.1. NM_001130831.1. [O60861-1 ]
NP_003635.2. NM_003644.2. [O60861-2 ]
NP_958836.1. NM_201432.1. [O60861-4 ]
NP_958839.1. NM_201433.1. [O60861-3 ]
XP_005256888.1. XM_005256831.2. [O60861-1 ]
XP_005256889.1. XM_005256832.2. [O60861-1 ]
UniGenei Hs.462214.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2LX7 NMR - A 1-60 [» ]
2YSH NMR - A 79-111 [» ]
ProteinModelPortali O60861.
SMRi O60861. Positions 1-131, 200-475.
ModBasei Search...

Protein-protein interaction databases

BioGridi 114094. 21 interactions.
IntActi O60861. 12 interactions.
MINTi MINT-1577125.
STRINGi 9606.ENSP00000322608.

PTM databases

PhosphoSitei O60861.

Proteomic databases

MaxQBi O60861.
PaxDbi O60861.
PRIDEi O60861.

Protocols and materials databases

DNASUi 8522.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000323816 ; ENSP00000322608 ; ENSG00000007237 . [O60861-4 ]
ENST00000432992 ; ENSP00000407552 ; ENSG00000007237 . [O60861-3 ]
ENST00000437099 ; ENSP00000410108 ; ENSG00000007237 . [O60861-1 ]
ENST00000542249 ; ENSP00000443265 ; ENSG00000007237 . [O60861-1 ]
ENST00000579158 ; ENSP00000463527 ; ENSG00000007237 . [O60861-1 ]
ENST00000580865 ; ENSP00000463873 ; ENSG00000007237 . [O60861-2 ]
ENST00000585266 ; ENSP00000464240 ; ENSG00000007237 . [O60861-4 ]
GeneIDi 8522.
KEGGi hsa:8522.
UCSCi uc002gmg.1. human. [O60861-3 ]
uc002gmh.1. human. [O60861-2 ]
uc002gmj.1. human. [O60861-4 ]

Organism-specific databases

CTDi 8522.
GeneCardsi GC17M009813.
HGNCi HGNC:4169. GAS7.
HPAi HPA004838.
MIMi 603127. gene.
neXtProti NX_O60861.
PharmGKBi PA28583.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG271795.
HOGENOMi HOG000294146.
HOVERGENi HBG001320.
InParanoidi O60861.
OMAi HMSLRKP.
OrthoDBi EOG7SN8CQ.
PhylomeDBi O60861.
TreeFami TF328986.

Enzyme and pathway databases

SignaLinki O60861.

Miscellaneous databases

ChiTaRSi GAS7. human.
EvolutionaryTracei O60861.
GeneWikii GAS7.
GenomeRNAii 8522.
NextBioi 31908.
PROi O60861.
SOURCEi Search...

Gene expression databases

ArrayExpressi O60861.
Bgeei O60861.
CleanExi HS_GAS7.
Genevestigatori O60861.

Family and domain databases

InterProi IPR001060. FCH_dom.
IPR001452. SH3_domain.
IPR001202. WW_dom.
[Graphical view ]
Pfami PF00611. FCH. 1 hit.
PF14604. SH3_9. 1 hit.
PF00397. WW. 1 hit.
[Graphical view ]
SMARTi SM00055. FCH. 1 hit.
SM00326. SH3. 1 hit.
SM00456. WW. 1 hit.
[Graphical view ]
SUPFAMi SSF50044. SSF50044. 1 hit.
SSF51045. SSF51045. 1 hit.
PROSITEi PS50133. FCH. 1 hit.
PS50002. SH3. 1 hit.
PS01159. WW_DOMAIN_1. 1 hit.
PS50020. WW_DOMAIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Human gas7: conservation of a mammalian growth-arrest-specific gene."
    Chao C.C.-K., Kuo J.T., Ju Y.-T., Lin-Chao S.
    Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
    Tissue: Cerebellum.
  2. "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro."
    Ishikawa K., Nagase T., Nakajima D., Seki N., Ohira M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 4:307-313(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4).
    Tissue: Brain.
  3. Shan Y.X., Yu L.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
  4. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
    Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 4).
    Tissue: Thalamus and Trachea.
  6. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Eye and Skin.
  9. "Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors."
    Megonigal M.D., Cheung N.-K.V., Rappaport E.F., Nowell P.C., Wilson R.B., Jones D.H., Addya K., Leonard D.G.B., Kushner B.H., Williams T.M., Lange B.J., Felix C.A.
    Proc. Natl. Acad. Sci. U.S.A. 97:2814-2819(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA], CHROMOSOMAL TRANSLOCATION WITH KMT2A/MLL1.
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-117, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  11. "Solution structure of the WW domain from the human growth-arrest-specific protein 7, GAS-7."
    RIKEN structural genomics initiative (RSGI)
    Submitted (OCT-2007) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 79-111.

Entry informationi

Entry nameiGAS7_HUMAN
AccessioniPrimary (citable) accession number: O60861
Secondary accession number(s): A8KAC2
, B2RCK9, O43144, Q53Y77, Q7Z571
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: December 16, 2008
Last modified: July 9, 2014
This is version 136 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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