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Protein

P antigen family member 4

Gene

PAGE4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
P antigen family member 4
Short name:
PAGE-4
Alternative name(s):
G antigen family C member 1
PAGE-1
Gene namesi
Name:PAGE4
Synonyms:GAGEC1
ORF Names:JM27
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000101951.16.
HGNCiHGNC:4108. PAGE4.

Pathology & Biotechi

Organism-specific databases

DisGeNETi9506.
OpenTargetsiENSG00000101951.
PharmGKBiPA28523.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001483481 – 102P antigen family member 4Add BLAST102

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei51PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiO60829.
PeptideAtlasiO60829.
PRIDEiO60829.

PTM databases

iPTMnetiO60829.
PhosphoSitePlusiO60829.

Expressioni

Tissue specificityi

Preferentially expressed in normal male and female reproductive tissues, prostate, testis, fallopian tube, uterus, and placenta, as well as in prostate cancer, testicular cancer, and uterine cancer.

Gene expression databases

BgeeiENSG00000101951.
CleanExiHS_PAGE4.
GenevisibleiO60829. HS.

Organism-specific databases

HPAiHPA023880.

Interactioni

Protein-protein interaction databases

BioGridi114884. 2 interactors.
STRINGi9606.ENSP00000218068.

Structurei

3D structure databases

ProteinModelPortaliO60829.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GAGE family.Curated

Phylogenomic databases

eggNOGiENOG410JFEF. Eukaryota.
ENOG41118BP. LUCA.
GeneTreeiENSGT00730000111680.
HOGENOMiHOG000237345.
InParanoidiO60829.
OMAiEMDLENT.
OrthoDBiEOG091G10JQ.
PhylomeDBiO60829.
TreeFamiTF340669.

Family and domain databases

InterProiView protein in InterPro
IPR031320. GAGE.
IPR008625. GAGE_fam.
PANTHERiPTHR14047. PTHR14047. 1 hit.
PfamiView protein in Pfam
PF05831. GAGE. 1 hit.
SMARTiView protein in SMART
SM01379. GAGE. 1 hit.

Sequencei

Sequence statusi: Complete.

O60829-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSARVRSRSR GRGDGQEAPD VVAFVAPGES QQEEPPTDNQ DIEPGQEREG
60 70 80 90 100
TPPIEERKVE GDCQEMDLEK TRSERGDGSD VKEKTPPNPK HAKTKEAGDG

QP
Length:102
Mass (Da):11,153
Last modified:August 1, 1998 - v1
Checksum:iCE5D07AFBF73301B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF275258 mRNA. Translation: AAF88037.1.
AJ005894 mRNA. Translation: CAA06751.1.
CR456823 mRNA. Translation: CAG33104.1.
CR542183 mRNA. Translation: CAG46980.1.
AK312039 mRNA. Translation: BAG34976.1.
AF238380 Genomic DNA. No translation available.
CH471180 Genomic DNA. Translation: EAW89932.1.
CH471180 Genomic DNA. Translation: EAW89933.1.
BC010897 mRNA. Translation: AAH10897.1.
CCDSiCCDS35274.1.
RefSeqiNP_001305806.1. NM_001318877.1.
NP_008934.1. NM_007003.4.
UniGeneiHs.441038.

Genome annotation databases

EnsembliENST00000218068; ENSP00000218068; ENSG00000101951.
ENST00000376141; ENSP00000365311; ENSG00000101951.
GeneIDi9506.
KEGGihsa:9506.
UCSCiuc004don.3. human.

Similar proteinsi

Entry informationi

Entry nameiPAGE4_HUMAN
AccessioniPrimary (citable) accession number: O60829
Secondary accession number(s): B2R529, D3DX68, Q6IBI1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: August 1, 1998
Last modified: September 27, 2017
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families