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O60829

- PAGE4_HUMAN

UniProt

O60829 - PAGE4_HUMAN

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Protein

P antigen family member 4

Gene
PAGE4, GAGEC1, JM27
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
P antigen family member 4
Short name:
PAGE-4
Alternative name(s):
G antigen family C member 1
PAGE-1
Gene namesi
Name:PAGE4
Synonyms:GAGEC1
ORF Names:JM27
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:4108. PAGE4.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28523.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 102102P antigen family member 4PRO_0000148348Add
BLAST

Proteomic databases

PaxDbiO60829.
PRIDEiO60829.

PTM databases

PhosphoSiteiO60829.

Expressioni

Tissue specificityi

Preferentially expressed in normal male and female reproductive tissues, prostate, testis, fallopian tube, uterus, and placenta, as well as in prostate cancer, testicular cancer, and uterine cancer.

Gene expression databases

BgeeiO60829.
CleanExiHS_PAGE4.
GenevestigatoriO60829.

Organism-specific databases

HPAiHPA023880.

Structurei

3D structure databases

ProteinModelPortaliO60829.

Family & Domainsi

Sequence similaritiesi

Belongs to the GAGE family.

Phylogenomic databases

eggNOGiNOG121161.
HOGENOMiHOG000237345.
InParanoidiO60829.
OMAiPERAKTK.
OrthoDBiEOG71K65D.
PhylomeDBiO60829.
TreeFamiTF340669.

Family and domain databases

InterProiIPR008625. GAGE.
[Graphical view]
PfamiPF05831. GAGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O60829-1 [UniParc]FASTAAdd to Basket

« Hide

MSARVRSRSR GRGDGQEAPD VVAFVAPGES QQEEPPTDNQ DIEPGQEREG    50
TPPIEERKVE GDCQEMDLEK TRSERGDGSD VKEKTPPNPK HAKTKEAGDG 100
QP 102
Length:102
Mass (Da):11,153
Last modified:August 1, 1998 - v1
Checksum:iCE5D07AFBF73301B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF275258 mRNA. Translation: AAF88037.1.
AJ005894 mRNA. Translation: CAA06751.1.
CR456823 mRNA. Translation: CAG33104.1.
CR542183 mRNA. Translation: CAG46980.1.
AK312039 mRNA. Translation: BAG34976.1.
AF238380 Genomic DNA. No translation available.
CH471180 Genomic DNA. Translation: EAW89932.1.
CH471180 Genomic DNA. Translation: EAW89933.1.
BC010897 mRNA. Translation: AAH10897.1.
CCDSiCCDS35274.1.
RefSeqiNP_008934.1. NM_007003.3.
XP_005272797.1. XM_005272740.1.
XP_005272798.1. XM_005272741.2.
XP_006724634.1. XM_006724571.1.
UniGeneiHs.441038.

Genome annotation databases

EnsembliENST00000218068; ENSP00000218068; ENSG00000101951.
ENST00000376141; ENSP00000365311; ENSG00000101951.
ENST00000595746; ENSP00000472606; ENSG00000268090.
ENST00000599013; ENSP00000472893; ENSG00000268090.
GeneIDi9506.
KEGGihsa:9506.
UCSCiuc004don.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF275258 mRNA. Translation: AAF88037.1 .
AJ005894 mRNA. Translation: CAA06751.1 .
CR456823 mRNA. Translation: CAG33104.1 .
CR542183 mRNA. Translation: CAG46980.1 .
AK312039 mRNA. Translation: BAG34976.1 .
AF238380 Genomic DNA. No translation available.
CH471180 Genomic DNA. Translation: EAW89932.1 .
CH471180 Genomic DNA. Translation: EAW89933.1 .
BC010897 mRNA. Translation: AAH10897.1 .
CCDSi CCDS35274.1.
RefSeqi NP_008934.1. NM_007003.3.
XP_005272797.1. XM_005272740.1.
XP_005272798.1. XM_005272741.2.
XP_006724634.1. XM_006724571.1.
UniGenei Hs.441038.

3D structure databases

ProteinModelPortali O60829.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei O60829.

Proteomic databases

PaxDbi O60829.
PRIDEi O60829.

Protocols and materials databases

DNASUi 9506.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000218068 ; ENSP00000218068 ; ENSG00000101951 .
ENST00000376141 ; ENSP00000365311 ; ENSG00000101951 .
ENST00000595746 ; ENSP00000472606 ; ENSG00000268090 .
ENST00000599013 ; ENSP00000472893 ; ENSG00000268090 .
GeneIDi 9506.
KEGGi hsa:9506.
UCSCi uc004don.1. human.

Organism-specific databases

CTDi 9506.
GeneCardsi GC0XP049593.
HGNCi HGNC:4108. PAGE4.
HPAi HPA023880.
MIMi 300287. gene.
neXtProti NX_O60829.
PharmGKBi PA28523.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG121161.
HOGENOMi HOG000237345.
InParanoidi O60829.
OMAi PERAKTK.
OrthoDBi EOG71K65D.
PhylomeDBi O60829.
TreeFami TF340669.

Miscellaneous databases

GenomeRNAii 9506.
NextBioi 35620.
PROi O60829.
SOURCEi Search...

Gene expression databases

Bgeei O60829.
CleanExi HS_PAGE4.
Genevestigatori O60829.

Family and domain databases

InterProi IPR008625. GAGE.
[Graphical view ]
Pfami PF05831. GAGE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "PAGE-1, an X chromosome-linked GAGE-like gene that is expressed in normal and neoplastic prostate, testis, and uterus."
    Brinkmann U., Vasmatzis G., Lee B., Yerushalmi N., Essand M., Pastan I.
    Proc. Natl. Acad. Sci. U.S.A. 95:10757-10762(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "Transcription map in Xp11.23."
    Strom T.M., Nyakatura G., Hellebrand H., Drescher B., Rosenthal A., Meindl A.
    Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Placenta.
  3. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Placenta.
  6. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Placenta.

Entry informationi

Entry nameiPAGE4_HUMAN
AccessioniPrimary (citable) accession number: O60829
Secondary accession number(s): B2R529, D3DX68, Q6IBI1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: August 1, 1998
Last modified: July 9, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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