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O60783 (RT14_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 106. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
28S ribosomal protein S14, mitochondrial

Short name=MRP-S14
Short name=S14mt
Gene names
Name:MRPS14
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length128 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins By similarity. UniProtKB Q6B860

Subcellular location

Mitochondrion.

Sequence similarities

Belongs to the ribosomal protein S14P family.

Ontologies

Binary interactions

With

Entry

#Exp.

IntAct

Notes

DDX56Q9NY931EBI-1045956,EBI-372376

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 12812828S ribosomal protein S14, mitochondrial
PRO_0000131013

Sequences

Sequence LengthMass (Da)Tools
O60783 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: FFF3F3C70214EDE4

FASTA12815,139
        10         20         30         40         50         60 
MAAFMLGSLL RTFKQMVPSS ASGQVRSHYV DWRMWRDVKR RKMAYEYADE RLRINSLRKN 

        70         80         90        100        110        120 
TILPKILQDV ADEEIAALPR DSCPVRIRNR CVMTSRPRGV KRRWRLSRIV FRHLADHGQL 


SGIQRATW 

« Hide

References

« Hide 'large scale' references
[1]Rhodes S.
Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Bone marrow.
[4]"A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins."
Koc E.C., Burkhart W., Blackburn K., Moseley A., Koc H., Spremulli L.L.
J. Biol. Chem. 275:32585-32591(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION.
[5]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL049705 mRNA. Translation: CAB41269.1.
Z99297 Genomic DNA. Translation: CAB16601.1.
BC009788 mRNA. Translation: AAH09788.1.
RefSeqNP_071383.1. NM_022100.2.
UniGeneHs.654858.

3D structure databases

ProteinModelPortalO60783.
SMRO60783. Positions 36-128.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid121999. 15 interactions.
IntActO60783. 5 interactions.
STRING9606.ENSP00000420714.

Proteomic databases

PaxDbO60783.
PeptideAtlasO60783.
PRIDEO60783.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000476371; ENSP00000420714; ENSG00000120333.
GeneID63931.
KEGGhsa:63931.
UCSCuc001gkk.3. human.

Organism-specific databases

CTD63931.
GeneCardsGC01M174979.
HGNCHGNC:14049. MRPS14.
HPAHPA051087.
MIM611978. gene.
neXtProtNX_O60783.
PharmGKBPA30998.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG0199.
HOGENOMHOG000039866.
HOVERGENHBG050074.
InParanoidO60783.
KOK02954.
OMAFGLCRNQ.
OrthoDBEOG7DVDDJ.
PhylomeDBO60783.
TreeFamTF320418.

Gene expression databases

ArrayExpressO60783.
BgeeO60783.
CleanExHS_MRPS14.
GenevestigatorO60783.

Family and domain databases

InterProIPR001209. Ribosomal_S14.
[Graphical view]
PANTHERPTHR19836. PTHR19836. 1 hit.
PfamPF00253. Ribosomal_S14. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi63931.
NextBio65682.
PROO60783.
SOURCESearch...

Entry information

Entry nameRT14_HUMAN
AccessionPrimary (citable) accession number: O60783
Secondary accession number(s): Q5R358
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: August 1, 1998
Last modified: April 16, 2014
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 1

Human chromosome 1: entries, gene names and cross-references to MIM