SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O60783

- RT14_HUMAN

UniProt

O60783 - RT14_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
28S ribosomal protein S14, mitochondrial
Gene
MRPS14
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. poly(A) RNA binding Source: UniProtKB
  2. structural constituent of ribosome Source: UniProtKB

GO - Biological processi

  1. translation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S14, mitochondrial
Short name:
MRP-S14
Short name:
S14mt
Gene namesi
Name:MRPS14
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:14049. MRPS14.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrial ribosome Source: UniProtKB
  2. mitochondrion Source: HPA
  3. nuclear membrane Source: HPA
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30998.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12812828S ribosomal protein S14, mitochondrial
PRO_0000131013Add
BLAST

Proteomic databases

MaxQBiO60783.
PaxDbiO60783.
PeptideAtlasiO60783.
PRIDEiO60783.

Expressioni

Gene expression databases

ArrayExpressiO60783.
BgeeiO60783.
CleanExiHS_MRPS14.
GenevestigatoriO60783.

Organism-specific databases

HPAiHPA051087.

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins By similarity.By similarity

Binary interactionsi

WithEntry#Exp.IntActNotes
DDX56Q9NY931EBI-1045956,EBI-372376

Protein-protein interaction databases

BioGridi121999. 15 interactions.
IntActiO60783. 5 interactions.
STRINGi9606.ENSP00000420714.

Structurei

3D structure databases

ProteinModelPortaliO60783.
SMRiO60783. Positions 36-128.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0199.
HOGENOMiHOG000039866.
HOVERGENiHBG050074.
InParanoidiO60783.
KOiK02954.
OMAiGHEAVAN.
OrthoDBiEOG7DVDDJ.
PhylomeDBiO60783.
TreeFamiTF320418.

Family and domain databases

InterProiIPR001209. Ribosomal_S14.
[Graphical view]
PANTHERiPTHR19836. PTHR19836. 1 hit.
PfamiPF00253. Ribosomal_S14. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O60783-1 [UniParc]FASTAAdd to Basket

« Hide

MAAFMLGSLL RTFKQMVPSS ASGQVRSHYV DWRMWRDVKR RKMAYEYADE    50
RLRINSLRKN TILPKILQDV ADEEIAALPR DSCPVRIRNR CVMTSRPRGV 100
KRRWRLSRIV FRHLADHGQL SGIQRATW 128
Length:128
Mass (Da):15,139
Last modified:August 1, 1998 - v1
Checksum:iFFF3F3C70214EDE4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL049705 mRNA. Translation: CAB41269.1.
Z99297 Genomic DNA. Translation: CAB16601.1.
BC009788 mRNA. Translation: AAH09788.1.
CCDSiCCDS1316.1.
RefSeqiNP_071383.1. NM_022100.2.
UniGeneiHs.654858.

Genome annotation databases

EnsembliENST00000476371; ENSP00000420714; ENSG00000120333.
GeneIDi63931.
KEGGihsa:63931.
UCSCiuc001gkk.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL049705 mRNA. Translation: CAB41269.1 .
Z99297 Genomic DNA. Translation: CAB16601.1 .
BC009788 mRNA. Translation: AAH09788.1 .
CCDSi CCDS1316.1.
RefSeqi NP_071383.1. NM_022100.2.
UniGenei Hs.654858.

3D structure databases

ProteinModelPortali O60783.
SMRi O60783. Positions 36-128.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 121999. 15 interactions.
IntActi O60783. 5 interactions.
STRINGi 9606.ENSP00000420714.

Proteomic databases

MaxQBi O60783.
PaxDbi O60783.
PeptideAtlasi O60783.
PRIDEi O60783.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000476371 ; ENSP00000420714 ; ENSG00000120333 .
GeneIDi 63931.
KEGGi hsa:63931.
UCSCi uc001gkk.3. human.

Organism-specific databases

CTDi 63931.
GeneCardsi GC01M174979.
HGNCi HGNC:14049. MRPS14.
HPAi HPA051087.
MIMi 611978. gene.
neXtProti NX_O60783.
PharmGKBi PA30998.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0199.
HOGENOMi HOG000039866.
HOVERGENi HBG050074.
InParanoidi O60783.
KOi K02954.
OMAi GHEAVAN.
OrthoDBi EOG7DVDDJ.
PhylomeDBi O60783.
TreeFami TF320418.

Miscellaneous databases

GenomeRNAii 63931.
NextBioi 65682.
PROi O60783.
SOURCEi Search...

Gene expression databases

ArrayExpressi O60783.
Bgeei O60783.
CleanExi HS_MRPS14.
Genevestigatori O60783.

Family and domain databases

InterProi IPR001209. Ribosomal_S14.
[Graphical view ]
PANTHERi PTHR19836. PTHR19836. 1 hit.
Pfami PF00253. Ribosomal_S14. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Rhodes S.
    Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Bone marrow.
  4. "A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins."
    Koc E.C., Burkhart W., Blackburn K., Moseley A., Koc H., Spremulli L.L.
    J. Biol. Chem. 275:32585-32591(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.
  5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRT14_HUMAN
AccessioniPrimary (citable) accession number: O60783
Secondary accession number(s): Q5R358
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: August 1, 1998
Last modified: July 9, 2014
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi