Reviewed, UniProtKB/Swiss-Prot O60688 (YPEL1_HUMAN)

Names and origin

Protein names

Recommended name:
    Protein yippee-like 1

Gene names

Name:	YPEL1
ORF Names:	FKSG3

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	119 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	May play a role in epithelioid conversion of fibroblasts.
Subcellular location	Nucleus By similarity.
Sequence similarities	Belongs to the yippee family.

Ontologies

Keywords
Cellular component	Nucleus
Gene Ontology (GO)
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 119	119	Protein yippee-like 1		PRO_0000212381
Regions
	Motif	99 – 104	6	Nuclear localization signal Potential
Experimental info
	Sequence conflict	108	1	E → D in AAH74501. Ref.6

Sequences

	Sequence		Length	Mass (Da)
	O60688-1 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: E91C058FA8C6D81F	FASTA	119	13,575
	10 20 30 40 50 60 MVKMTKSKTF QAYLPNCHRT YSCIHCRAHL ANHDELISKS FQGSQGRAYL FNSVVNVGCG 70 80 90 100 110 PAEERVLLTG LHAVADIYCE NCKTTLGWKY EHAFESSQKY KEGKFIIELA HMIKDNGWE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species." Hosono K., Sasaki T., Minoshima S., Shimizu N. Gene 340:31-43(2004) [PubMed: 15556292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Human unknown cDNA, complete cds." Hu G., Hui L. Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]	"Cloning and characterization of FKSG3, a novel gene related to DiGeorge syndrome." Wang Y.-G. Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[4]	"A genome annotation-driven approach to cloning the human ORFeome." Collins J.E., Wright C.L., Edwards C.A., Davis M.P., Grinham J.A., Cole C.G., Goward M.E., Aguado B., Mallya M., Mokrab Y., Huckle E.J., Beare D.M., Dunham I. Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004) [PubMed: 15461802] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Blocker H., Heubner D., Hoerlein A., Michel G., Wedler H., Kohrer K., Ottenwalder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed: 17974005] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Fetal kidney.
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain and Testis.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB098734 mRNA. Translation: BAD51375.1. AB098735 mRNA. Translation: BAD51376.1. AF060862 mRNA. Translation: AAC15461.1. AF305069 mRNA. Translation: AAL09353.1. CR456376 mRNA. Translation: CAG30262.1. CR933630 Transcribed RNA. Translation: CAI45937.1. BC034486 mRNA. Translation: AAH34486.1. BC074501 mRNA. Translation: AAH74501.1.
IPI	IPI00743468.
PIR	T50835.
RefSeq	NP_037445.1.
UniGene	Hs.517436
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	O60688.
Genome annotation databases
Ensembl	ENSG00000100027. Homo sapiens. [Contig view]
GeneID	29799.
KEGG	hsa:29799.
Organism-specific databases
GeneCards	GC22M020381.
HGNC	HGNC:12845. YPEL1.
MIM	608082. gene.
PharmGKB	PA37436.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	O60688.
OMA	O60688. SDIYCEN.
Gene expression databases
ArrayExpress	O60688.
Bgee	O60688.
CleanEx	HS_YPEL1.
GermOnline	ENSG00000100027. Homo sapiens.
Family and domain databases
InterPro	IPR004910. Yippee. [Graphical view]
Pfam	PF03226. Yippee. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	52343.
SOURCE	Search...

Entry information

Entry name

YPEL1_HUMAN

Accession

Primary (citable) accession number: O60688
Secondary accession number(s): Q65ZA1, Q6GLI6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 17, 2003
Last sequence update:	August 1, 1998
Last modified:	June 16, 2009
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)