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O60664

- PLIN3_HUMAN

UniProt

O60664 - PLIN3_HUMAN

Protein

Perilipin-3

Gene

PLIN3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 138 (01 Oct 2014)
      Sequence version 3 (11 Jan 2011)
      Previous versions | rss
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    Functioni

    Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.1 Publication

    GO - Molecular functioni

    1. protein binding Source: UniProtKB

    GO - Biological processi

    1. vesicle-mediated transport Source: ProtInc

    Keywords - Biological processi

    Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Perilipin-3
    Alternative name(s):
    47 kDa mannose 6-phosphate receptor-binding protein
    Short name:
    47 kDa MPR-binding protein
    Cargo selection protein TIP47
    Mannose-6-phosphate receptor-binding protein 1
    Placental protein 17
    Short name:
    PP17
    Gene namesi
    Name:PLIN3
    Synonyms:M6PRBP1, TIP47
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:16893. PLIN3.

    Subcellular locationi

    Cytoplasm 2 Publications. Endosome membrane Curated; Peripheral membrane protein Curated; Cytoplasmic side Curated. Lipid droplet Curated
    Note: Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails.

    GO - Cellular componenti

    1. cytoplasm Source: HPA
    2. endosome Source: ProtInc
    3. endosome membrane Source: UniProtKB-SubCell
    4. Golgi apparatus Source: ProtInc
    5. intracellular membrane-bounded organelle Source: HPA
    6. lipid particle Source: UniProtKB
    7. membrane Source: UniProtKB

    Keywords - Cellular componenti

    Cytoplasm, Endosome, Lipid droplet, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA165394001.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed3 Publications
    Chaini2 – 434433Perilipin-3PRO_0000099890Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylserine3 Publications
    Modified residuei65 – 651N6-acetyllysine1 Publication
    Modified residuei130 – 1301Phosphoserine2 Publications
    Modified residuei170 – 1701Phosphothreonine1 Publication
    Modified residuei175 – 1751Phosphoserine1 Publication
    Modified residuei179 – 1791Phosphoserine1 Publication

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    MaxQBiO60664.
    PaxDbiO60664.
    PRIDEiO60664.

    2D gel databases

    REPRODUCTION-2DPAGEIPI00303882.

    PTM databases

    PhosphoSiteiO60664.

    Miscellaneous databases

    PMAP-CutDBO60664.

    Expressioni

    Gene expression databases

    ArrayExpressiO60664.
    BgeeiO60664.
    CleanExiHS_M6PRBP1.
    GenevestigatoriO60664.

    Organism-specific databases

    HPAiHPA006427.

    Interactioni

    Subunit structurei

    Homooligomer. Interacts with M6PR (via the cytoplasmic domain). Interacts with IGF2R (via the cytoplasmic domain). Isoform 2 may exist as a homodimer (known as PP17C).1 Publication

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    Q9WMX25EBI-725795,EBI-6863748From a different organism.

    Protein-protein interaction databases

    BioGridi115520. 45 interactions.
    IntActiO60664. 10 interactions.
    MINTiMINT-5000803.
    STRINGi9606.ENSP00000221957.

    Structurei

    3D structure databases

    ProteinModelPortaliO60664.
    SMRiO60664. Positions 202-427.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili252 – 27726Sequence AnalysisAdd
    BLAST
    Coiled coili353 – 37725Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the perilipin family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG81115.
    HOGENOMiHOG000033816.
    HOVERGENiHBG002935.
    InParanoidiO60664.
    OMAiQEQSYFV.
    OrthoDBiEOG7SN8CD.
    PhylomeDBiO60664.
    TreeFamiTF328397.

    Family and domain databases

    InterProiIPR004279. Perilipin.
    [Graphical view]
    PANTHERiPTHR14024. PTHR14024. 1 hit.
    PfamiPF03036. Perilipin. 1 hit.
    [Graphical view]
    PIRSFiPIRSF036881. PAT. 1 hit.

    Sequences (4)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: O60664-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MSADGAEADG STQVTVEEPV QQPSVVDRVA SMPLISSTCD MVSAAYASTK    50
    ESYPHIKTVC DAAEKGVRTL TAAAVSGAQP ILSKLEPQIA SASEYAHRGL 100
    DKLEENLPIL QQPTEKVLAD TKELVSSKVS GAQEMVSSAK DTVATQLSEA 150
    VDATRGAVQS GVDKTKSVVT GGVQSVMGSR LGQMVLSGVD TVLGKSEEWA 200
    DNHLPLTDAE LARIATSLDG FDVASVQQQR QEQSYFVRLG SLSERLRQHA 250
    YEHSLGKLRA TKQRAQEALL QLSQVLSLME TVKQGVDQKL VEGQEKLHQM 300
    WLSWNQKQLQ GPEKEPPKPE QVESRALTMF RDIAQQLQAT CTSLGSSIQG 350
    LPTNVKDQVQ QARRQVEDLQ ATFSSIHSFQ DLSSSILAQS RERVASAREA 400
    LDHMVEYVAQ NTPVTWLVGP FAPGITEKAP EEKK 434

    Note: PP17b.

    Length:434
    Mass (Da):47,075
    Last modified:January 11, 2011 - v3
    Checksum:i67B2B9CDBC523043
    GO
    Isoform 2 (identifier: O60664-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-183: Missing.

    Note: PP17a.

    Show »
    Length:251
    Mass (Da):28,158
    Checksum:i3C7AEC3FBE9429DF
    GO
    Isoform 3 (identifier: O60664-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         321-321: Missing.

    Show »
    Length:433
    Mass (Da):46,947
    Checksum:i8716B72B11C7FE65
    GO
    Isoform 4 (identifier: O60664-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         116-127: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:422
    Mass (Da):45,803
    Checksum:iDB98F133BF2A206E
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti77 – 771G → W in AAD11622. (PubMed:9874244)Curated
    Sequence conflicti109 – 1113ILQ → MLR in AAD11622. (PubMed:9874244)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti56 – 561I → V.4 Publications
    Corresponds to variant rs8289 [ dbSNP | Ensembl ].
    VAR_022780
    Natural varianti275 – 2751V → A.7 Publications
    Corresponds to variant rs9973235 [ dbSNP | Ensembl ].
    VAR_024559

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 183183Missing in isoform 2. 2 PublicationsVSP_004664Add
    BLAST
    Alternative sequencei116 – 12712Missing in isoform 4. CuratedVSP_047038Add
    BLAST
    Alternative sequencei321 – 3211Missing in isoform 3. 1 PublicationVSP_040325

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF057140 mRNA. Translation: AAC39751.1.
    AF055574 mRNA. Translation: AAD11622.1.
    AF051314 mRNA. Translation: AAD11619.1.
    AF051315 mRNA. Translation: AAD11620.1.
    BT007235 mRNA. Translation: AAP35899.1.
    AK291104 mRNA. Translation: BAF83793.1.
    AK223054 mRNA. Translation: BAD96774.1.
    AK225045 mRNA. No translation available.
    AC027319 Genomic DNA. No translation available.
    BC001590 mRNA. Translation: AAH01590.1.
    BC005818 mRNA. Translation: AAH05818.1.
    BC007566 mRNA. Translation: AAH07566.1.
    BC019278 mRNA. Translation: AAH19278.1.
    CCDSiCCDS12137.1. [O60664-1]
    CCDS59337.1. [O60664-4]
    CCDS59338.1. [O60664-3]
    RefSeqiNP_001157661.1. NM_001164189.1. [O60664-3]
    NP_001157666.1. NM_001164194.1. [O60664-4]
    NP_005808.3. NM_005817.4. [O60664-1]
    UniGeneiHs.140452.

    Genome annotation databases

    EnsembliENST00000221957; ENSP00000221957; ENSG00000105355. [O60664-1]
    ENST00000585479; ENSP00000465596; ENSG00000105355. [O60664-3]
    ENST00000592528; ENSP00000467803; ENSG00000105355. [O60664-4]
    GeneIDi10226.
    KEGGihsa:10226.
    UCSCiuc002mbj.2. human. [O60664-1]
    uc002mbl.3. human. [O60664-3]

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF057140 mRNA. Translation: AAC39751.1 .
    AF055574 mRNA. Translation: AAD11622.1 .
    AF051314 mRNA. Translation: AAD11619.1 .
    AF051315 mRNA. Translation: AAD11620.1 .
    BT007235 mRNA. Translation: AAP35899.1 .
    AK291104 mRNA. Translation: BAF83793.1 .
    AK223054 mRNA. Translation: BAD96774.1 .
    AK225045 mRNA. No translation available.
    AC027319 Genomic DNA. No translation available.
    BC001590 mRNA. Translation: AAH01590.1 .
    BC005818 mRNA. Translation: AAH05818.1 .
    BC007566 mRNA. Translation: AAH07566.1 .
    BC019278 mRNA. Translation: AAH19278.1 .
    CCDSi CCDS12137.1. [O60664-1 ]
    CCDS59337.1. [O60664-4 ]
    CCDS59338.1. [O60664-3 ]
    RefSeqi NP_001157661.1. NM_001164189.1. [O60664-3 ]
    NP_001157666.1. NM_001164194.1. [O60664-4 ]
    NP_005808.3. NM_005817.4. [O60664-1 ]
    UniGenei Hs.140452.

    3D structure databases

    ProteinModelPortali O60664.
    SMRi O60664. Positions 202-427.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 115520. 45 interactions.
    IntActi O60664. 10 interactions.
    MINTi MINT-5000803.
    STRINGi 9606.ENSP00000221957.

    Chemistry

    DrugBanki DB01279. Galsulfase.
    DB01271. Idursulfase.

    PTM databases

    PhosphoSitei O60664.

    2D gel databases

    REPRODUCTION-2DPAGE IPI00303882.

    Proteomic databases

    MaxQBi O60664.
    PaxDbi O60664.
    PRIDEi O60664.

    Protocols and materials databases

    DNASUi 10226.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000221957 ; ENSP00000221957 ; ENSG00000105355 . [O60664-1 ]
    ENST00000585479 ; ENSP00000465596 ; ENSG00000105355 . [O60664-3 ]
    ENST00000592528 ; ENSP00000467803 ; ENSG00000105355 . [O60664-4 ]
    GeneIDi 10226.
    KEGGi hsa:10226.
    UCSCi uc002mbj.2. human. [O60664-1 ]
    uc002mbl.3. human. [O60664-3 ]

    Organism-specific databases

    CTDi 10226.
    GeneCardsi GC19M004839.
    H-InvDB HIX0014673.
    HGNCi HGNC:16893. PLIN3.
    HPAi HPA006427.
    MIMi 602702. gene.
    neXtProti NX_O60664.
    PharmGKBi PA165394001.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG81115.
    HOGENOMi HOG000033816.
    HOVERGENi HBG002935.
    InParanoidi O60664.
    OMAi QEQSYFV.
    OrthoDBi EOG7SN8CD.
    PhylomeDBi O60664.
    TreeFami TF328397.

    Miscellaneous databases

    ChiTaRSi PLIN3. human.
    GeneWikii M6PRBP1.
    GenomeRNAii 10226.
    NextBioi 38722.
    PMAP-CutDB O60664.
    PROi O60664.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi O60664.
    Bgeei O60664.
    CleanExi HS_M6PRBP1.
    Genevestigatori O60664.

    Family and domain databases

    InterProi IPR004279. Perilipin.
    [Graphical view ]
    PANTHERi PTHR14024. PTHR14024. 1 hit.
    Pfami PF03036. Perilipin. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF036881. PAT. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking."
      Diaz E., Pfeffer S.R.
      Cell 93:433-443(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANTS VAL-56 AND ALA-275, FUNCTION, INTERACTION WITH M6PR AND IGF2R, HOMOOLIGOMERIZATION, SUBCELLULAR LOCATION.
    2. "Cloning and sequence analysis of cDNAs encoding human placental tissue protein 17 (PP17) variants."
      Than N.G., Sumegi B., Than G.N., Kispal G., Bohn H.
      Eur. J. Biochem. 258:752-757(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), VARIANTS VAL-56 AND ALA-275.
      Tissue: Placenta.
    3. "Cloning and sequencing of human oncodevelopmental soluble placental tissue protein 17 (PP17): homology with adipophilin and the mouse adipose differentiation-related protein."
      Than N.G., Sumegi B., Than G.N., Kispal G., Bohn H.
      Tumor Biol. 20:184-192(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), VARIANTS VAL-56 AND ALA-275.
      Tissue: Placenta.
    4. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
      Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT ALA-275.
    5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT ALA-275.
    6. Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
      Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), VARIANT ALA-275.
    7. "The DNA sequence and biology of human chromosome 19."
      Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
      , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
      Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS VAL-56 AND ALA-275.
      Tissue: Colon and Muscle.
    9. "Purification and characterization of two new soluble placental tissue proteins (PP13 and PP17)."
      Bohn H., Kraus W., Winckler W.
      Oncodev. Biol. Med. 4:343-350(1983) [PubMed] [Europe PMC] [Abstract]
      Cited for: CHARACTERIZATION.
      Tissue: Placenta.
    10. "Spatial integration of TIP47 and adipophilin in macrophage lipid bodies."
      Robenek H., Lorkowski S., Schnoor M., Troyer D.
      J. Biol. Chem. 280:5789-5794(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION.
    11. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-130; THR-170; SER-175 AND SER-179, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    12. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
    13. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
      Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-65, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-130, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    15. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    16. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
      Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    17. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiPLIN3_HUMAN
    AccessioniPrimary (citable) accession number: O60664
    Secondary accession number(s): A8K4Y9
    , K7EQF4, Q53G77, Q9BS03, Q9UBD7, Q9UP92
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: January 11, 2011
    Last modified: October 1, 2014
    This is version 138 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

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