Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O60641

- AP180_HUMAN

UniProt

O60641 - AP180_HUMAN

Protein

Clathrin coat assembly protein AP180

Gene

SNAP91

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 122 (01 Oct 2014)
      Sequence version 2 (01 Aug 1999)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia induces their assembly into 60-70 nm coats By similarity.By similarity

    GO - Molecular functioni

    1. 1-phosphatidylinositol binding Source: InterPro
    2. protein binding Source: IntAct
    3. protein kinase binding Source: ParkinsonsUK-UCL

    GO - Biological processi

    1. clathrin coat assembly Source: InterPro
    2. protein transport Source: UniProtKB-KW

    Keywords - Biological processi

    Protein transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Clathrin coat assembly protein AP180
    Alternative name(s):
    91 kDa synaptosomal-associated protein
    Clathrin coat-associated protein AP180
    Phosphoprotein F1-20
    Gene namesi
    Name:SNAP91
    Synonyms:KIAA0656
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 6

    Organism-specific databases

    HGNCiHGNC:14986. SNAP91.

    Subcellular locationi

    Cell membrane By similarity. Membranecoated pit By similarity; Peripheral membrane protein By similarity; Cytoplasmic side By similarity
    Note: Component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane.By similarity

    GO - Cellular componenti

    1. clathrin coat Source: InterPro
    2. coated pit Source: UniProtKB-SubCell
    3. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Coated pit, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA37956.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 907907Clathrin coat assembly protein AP180PRO_0000193864Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei306 – 3061PhosphoserineBy similarity
    Glycosylationi310 – 3101O-linked (GlcNAc)By similarity
    Modified residuei313 – 3131PhosphoserineBy similarity
    Modified residuei602 – 6021PhosphoserineBy similarity
    Modified residuei623 – 6231PhosphoserineBy similarity
    Modified residuei629 – 6291PhosphoserineBy similarity

    Post-translational modificationi

    Thr-310 can be modified by the addition of N-acetylglucosamine which can be further phosphorylated. There is no evidence for direct Thr-310 phosphorylation By similarity.By similarity

    Keywords - PTMi

    Glycoprotein, Phosphoprotein

    Proteomic databases

    MaxQBiO60641.
    PaxDbiO60641.
    PRIDEiO60641.

    PTM databases

    PhosphoSiteiO60641.

    Expressioni

    Gene expression databases

    ArrayExpressiO60641.
    BgeeiO60641.
    CleanExiHS_SNAP91.
    GenevestigatoriO60641.

    Organism-specific databases

    HPAiCAB009745.
    HPA029632.
    HPA029633.

    Interactioni

    Subunit structurei

    Binds AP2A2. Interacts with AP2B1; clathrin competes with SNAP91 By similarity.By similarity

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    Necap1Q9CR952EBI-1105187,EBI-7592476From a different organism.

    Protein-protein interaction databases

    BioGridi115222. 5 interactions.
    IntActiO60641. 3 interactions.
    MINTiMINT-3000172.
    STRINGi9606.ENSP00000195649.

    Structurei

    3D structure databases

    ProteinModelPortaliO60641.
    SMRiO60641. Positions 18-264.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini14 – 145132ENTHPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi361 – 583223Ala-richAdd
    BLAST
    Compositional biasi536 – 55621Thr-richAdd
    BLAST
    Compositional biasi809 – 89789Pro-richAdd
    BLAST

    Domaini

    Possesses a three domain structure: the N-terminal 300 residues harbor a clathrin binding site, an acidic middle domain 450 residues, interrupted by an Ala-rich segment, and the C-terminal domain (166 residues).

    Sequence similaritiesi

    Belongs to the PICALM/SNAP91 family.Curated
    Contains 1 ENTH (epsin N-terminal homology) domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG267212.
    HOGENOMiHOG000015763.
    HOVERGENiHBG049391.
    InParanoidiO60641.
    OMAiXRISGAP.
    OrthoDBiEOG76QFM8.
    PhylomeDBiO60641.
    TreeFamiTF314861.

    Family and domain databases

    Gene3Di1.20.58.150. 1 hit.
    1.25.40.90. 1 hit.
    InterProiIPR011417. ANTH_dom.
    IPR014712. Clathrin_Pinositid-bd_GAT-like.
    IPR008942. ENTH_VHS.
    IPR013809. Epsin-like_N.
    [Graphical view]
    PfamiPF07651. ANTH. 1 hit.
    [Graphical view]
    SMARTiSM00273. ENTH. 1 hit.
    [Graphical view]
    SUPFAMiSSF48464. SSF48464. 1 hit.
    PROSITEiPS50942. ENTH. 1 hit.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: O60641-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MSGQTLTDRI AAAQYSVTGS AVARAVCKAT THEVMGPKKK HLDYLIQATN    50
    ETNVNIPQMA DTLFERATNS SWVVVFKALV TTHHLMVHGN ERFIQYLASR 100
    NTLFNLSNFL DKSGSHGYDM STFIRRYSRY LNEKAFSYRQ MAFDFARVKK 150
    GADGVMRTMA PEKLLKSMPI LQGQIDALLE FDVHPNELTN GVINAAFMLL 200
    FKDLIKLFAC YNDGVINLLE KFFEMKKGQC KDALEIYKRF LTRMTRVSEF 250
    LKVAEQVGID KGDIPDLTQA PSSLMETLEQ HLNTLEGKKP GNNEGSGAPS 300
    PLSKSSPATT VTSPNSTPAK TIDTSPPVDL FATASAAVPV STSKPSSDLL 350
    DLQPDFSSGG AAAAAAPAPP PPAGGATAWG DLLGEDSLAA LSSVPSEAQI 400
    SDPFAPEPTP PTTTAEIATA SASASTTTTV TAVTAEVDLF GDAFAASPGE 450
    APAASEGAAA PATPTPVAAA LDACSGNDPF APSEGSAEAA PELDLFAMKP 500
    PETSVPVVTP TASTAPPVPA TAPSPAPAVA AAAAATTAAT AAATTTTTTS 550
    AATATTAPPA LDIFGDLFES TPEVAAAPKP DAAPSIDLFS TDAFSSPPQG 600
    ASPVPESSLT ADLLSVDAFA APSPATTASP AKVDSSGVID LFGDAFGSSA 650
    SEPQPASQAA SSSSASADLL AGFGGSFMAP SPSPVTPAQN NLLQPNFEAA 700
    FGTTPSTSSS SSFDPSVFDG LGDLLMPTMA PAGQPAPVSM VPPSPAMAAS 750
    KALGSDLDSS LASLVGNLGI SGTTTKKGDL QWNAGEKKLT GGANWQPKVA 800
    PATWSAGVPP SAPLQGAVPP TSSVPPVAGA PSVGQPGAGF GMPPAGTGMP 850
    MMPQQPVMFA QPMMRPPFGA AAVPGTQLSP SPTPASQSPK KPPAKDPLAD 900
    LNIKDFL 907
    Length:907
    Mass (Da):92,502
    Last modified:August 1, 1999 - v2
    Checksum:i23959C2B54F5EBF1
    GO
    Isoform 2 (identifier: O60641-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         59-907: Missing.

    Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

    Show »
    Length:58
    Mass (Da):6,230
    Checksum:i22EBDA4093641147
    GO
    Isoform 3 (identifier: O60641-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         256-269: Missing.
         293-295: NEG → K
         381-671: Missing.

    Show »
    Length:600
    Mass (Da):63,128
    Checksum:i0B92B5140631B77F
    GO
    Isoform 4 (identifier: O60641-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         293-295: NEG → K
         616-643: Missing.

    Note: Gene prediction based on EST data.

    Show »
    Length:877
    Mass (Da):89,656
    Checksum:iA9A46C044BE55582
    GO

    Sequence cautioni

    The sequence BAA31631.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence CAB89292.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti4 – 41Q → R in AAH60818. (PubMed:15489334)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei59 – 907849Missing in isoform 2. 1 PublicationVSP_020997Add
    BLAST
    Alternative sequencei256 – 26914Missing in isoform 3. 1 PublicationVSP_020998Add
    BLAST
    Alternative sequencei293 – 2953NEG → K in isoform 3 and isoform 4. 1 PublicationVSP_020999
    Alternative sequencei381 – 671291Missing in isoform 3. 1 PublicationVSP_021000Add
    BLAST
    Alternative sequencei616 – 64328Missing in isoform 4. CuratedVSP_047049Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB014556 mRNA. Translation: BAA31631.2. Different initiation.
    AK289582 mRNA. Translation: BAF82271.1.
    CR749348 mRNA. Translation: CAH18201.1. Sequence problems.
    AL109915 Genomic DNA. Translation: CAB89292.1. Sequence problems.
    AL109915 Genomic DNA. Translation: CAI19453.1.
    AL136972 Genomic DNA. No translation available.
    AF054993 mRNA. Translation: AAC09352.1.
    BC060818 mRNA. Translation: AAH60818.1.
    CCDSiCCDS47455.1. [O60641-1]
    CCDS56437.1. [O60641-3]
    CCDS56438.1. [O60641-4]
    RefSeqiNP_001229721.1. NM_001242792.1. [O60641-1]
    NP_001229722.1. NM_001242793.1. [O60641-4]
    NP_001229723.1. NM_001242794.1. [O60641-3]
    NP_001243646.1. NM_001256717.1.
    NP_001243647.1. NM_001256718.1.
    NP_055656.1. NM_014841.2. [O60641-1]
    XP_005248827.1. XM_005248770.2. [O60641-1]
    XP_006715678.1. XM_006715615.1. [O60641-1]
    UniGeneiHs.368046.

    Genome annotation databases

    EnsembliENST00000369694; ENSP00000358708; ENSG00000065609. [O60641-1]
    ENST00000439399; ENSP00000400459; ENSG00000065609. [O60641-1]
    ENST00000520213; ENSP00000428026; ENSG00000065609. [O60641-3]
    ENST00000520302; ENSP00000428511; ENSG00000065609. [O60641-4]
    ENST00000521743; ENSP00000428215; ENSG00000065609. [O60641-1]
    GeneIDi9892.
    KEGGihsa:9892.
    UCSCiuc003pka.3. human. [O60641-1]
    uc003pkd.3. human. [O60641-3]

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB014556 mRNA. Translation: BAA31631.2 . Different initiation.
    AK289582 mRNA. Translation: BAF82271.1 .
    CR749348 mRNA. Translation: CAH18201.1 . Sequence problems.
    AL109915 Genomic DNA. Translation: CAB89292.1 . Sequence problems.
    AL109915 Genomic DNA. Translation: CAI19453.1 .
    AL136972 Genomic DNA. No translation available.
    AF054993 mRNA. Translation: AAC09352.1 .
    BC060818 mRNA. Translation: AAH60818.1 .
    CCDSi CCDS47455.1. [O60641-1 ]
    CCDS56437.1. [O60641-3 ]
    CCDS56438.1. [O60641-4 ]
    RefSeqi NP_001229721.1. NM_001242792.1. [O60641-1 ]
    NP_001229722.1. NM_001242793.1. [O60641-4 ]
    NP_001229723.1. NM_001242794.1. [O60641-3 ]
    NP_001243646.1. NM_001256717.1.
    NP_001243647.1. NM_001256718.1.
    NP_055656.1. NM_014841.2. [O60641-1 ]
    XP_005248827.1. XM_005248770.2. [O60641-1 ]
    XP_006715678.1. XM_006715615.1. [O60641-1 ]
    UniGenei Hs.368046.

    3D structure databases

    ProteinModelPortali O60641.
    SMRi O60641. Positions 18-264.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 115222. 5 interactions.
    IntActi O60641. 3 interactions.
    MINTi MINT-3000172.
    STRINGi 9606.ENSP00000195649.

    PTM databases

    PhosphoSitei O60641.

    Proteomic databases

    MaxQBi O60641.
    PaxDbi O60641.
    PRIDEi O60641.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000369694 ; ENSP00000358708 ; ENSG00000065609 . [O60641-1 ]
    ENST00000439399 ; ENSP00000400459 ; ENSG00000065609 . [O60641-1 ]
    ENST00000520213 ; ENSP00000428026 ; ENSG00000065609 . [O60641-3 ]
    ENST00000520302 ; ENSP00000428511 ; ENSG00000065609 . [O60641-4 ]
    ENST00000521743 ; ENSP00000428215 ; ENSG00000065609 . [O60641-1 ]
    GeneIDi 9892.
    KEGGi hsa:9892.
    UCSCi uc003pka.3. human. [O60641-1 ]
    uc003pkd.3. human. [O60641-3 ]

    Organism-specific databases

    CTDi 9892.
    GeneCardsi GC06M084319.
    H-InvDB HIX0006038.
    HGNCi HGNC:14986. SNAP91.
    HPAi CAB009745.
    HPA029632.
    HPA029633.
    MIMi 607923. gene.
    neXtProti NX_O60641.
    PharmGKBi PA37956.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG267212.
    HOGENOMi HOG000015763.
    HOVERGENi HBG049391.
    InParanoidi O60641.
    OMAi XRISGAP.
    OrthoDBi EOG76QFM8.
    PhylomeDBi O60641.
    TreeFami TF314861.

    Miscellaneous databases

    GeneWikii SNAP91.
    GenomeRNAii 9892.
    NextBioi 37299.
    PROi O60641.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi O60641.
    Bgeei O60641.
    CleanExi HS_SNAP91.
    Genevestigatori O60641.

    Family and domain databases

    Gene3Di 1.20.58.150. 1 hit.
    1.25.40.90. 1 hit.
    InterProi IPR011417. ANTH_dom.
    IPR014712. Clathrin_Pinositid-bd_GAT-like.
    IPR008942. ENTH_VHS.
    IPR013809. Epsin-like_N.
    [Graphical view ]
    Pfami PF07651. ANTH. 1 hit.
    [Graphical view ]
    SMARTi SM00273. ENTH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48464. SSF48464. 1 hit.
    PROSITEi PS50942. ENTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
      Ishikawa K., Nagase T., Suyama M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
      DNA Res. 5:169-176(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Brain.
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Cerebellum.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Testis.
    4. "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
      , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
      Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
      Tissue: Testis.
    6. Yu W., Gibbs R.A.
      Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 794-907.
      Tissue: Brain.
    7. "Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly."
      Schmid E.M., Ford M.G.J., Burtey A., Praefcke G.J.K., Peak-Chew S.-Y., Mills I.G., Benmerah A., McMahon H.T.
      PLoS Biol. 4:E262-E262(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH AP2B1.

    Entry informationi

    Entry nameiAP180_HUMAN
    AccessioniPrimary (citable) accession number: O60641
    Secondary accession number(s): A8K0L7
    , E5RI02, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 17, 2003
    Last sequence update: August 1, 1999
    Last modified: October 1, 2014
    This is version 122 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 6
      Human chromosome 6: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3