O60574 (O60574_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cadherin-7 EMBL AAC05117.1

Gene names

Name:

CDH7 EMBL AAC05117.1

Organism

Homo sapiens (Human) EMBL AAC05117.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	317 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Cadherins are calcium dependent cell adhesion proteins By similarity.
Subcellular location	Membrane; Single-pass type I membrane protein By similarity RuleBase RU003318.

Ontologies

Keywords
Biological process	Cell adhesion RuleBase RU003318
Cellular component	Cell membrane SAAS SAAS002126 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS002126
Ligand	Calcium RuleBase RU000484 RuleBase RU003318
Gene Ontology (GO)
Biological_process	homophilic cell adhesion Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAC05117.1

Sequences

	Sequence		Length	Mass (Da)
	O60574 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: F75855DCC0EAB5BE	FASTA	317	35,575
	10 20 30 40 50 60 GTRQVLNIND HAPEFSQYYE TYVCENAGSG QVIQTISAVD RDESIEEHHF YFNLSVEDTN 70 80 90 100 110 120 NSSFTIIDNQ DNTAVILTNR TGFNLQEEPV FYISILIADN GIPSLTSTNT LTIHVCDCGD 130 140 150 160 170 180 SGSTQTCQYQ ELVLSMGFKT EVIIAILICI MIIFGFIFLT LGLKQRRKQI LFPEKSEDFR 190 200 210 220 230 240 ENIFQYDDEG GGEEDTEAFD IAELRSSTIM RERKTRKTTS AEIRSLYRQS LQVGPDSAIF 250 260 270 280 290 300 RKFILEKLEE ANTDPCAPPF DSLQTYAFEG TGSLAGSLSS LESAVSDQDE SYDYLNELGP 310 RFKRLACMFG SAVQSNN

References

[1]	"Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity." Kremmidiotis G., Baker E., Crawford J., Eyre H.J., Nahmias J., Callen D.F. Genomics 49:467-471(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF047826 mRNA. Translation: AAC05117.1.
IPI	IPI00028135.
UniGene	Hs.42771.
3D structure databases
HSSP	HSSP built from PDB template 1I7X based on UniProtKB P09803.
ProteinModelPortal	O60574.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG005217.
Family and domain databases
Gene3D	2.60.40.60. 1 hit.
InterPro	IPR002126. Cadherin. IPR015919. Cadherin-like. IPR000233. Cadherin_cytoplasmic-dom. [Graphical view]
Pfam	PF00028. Cadherin. 1 hit. PF01049. Cadherin_C. 1 hit. [Graphical view]
SMART	SM00112. CA. 1 hit. [Graphical view]
SUPFAM	SSF49313. Cadherin. 1 hit.
PROSITE	PS50268. CADHERIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O60574_HUMAN

Accession

Primary (citable) accession number: O60574

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	August 1, 1998
Last modified:	April 3, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.