O60352 (O60352_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase EMBL BAA25289.1 EC=2.7.1.105 EMBL BAA25289.1 EC=3.1.3.46 EMBL BAA25289.1
Organism	Homo sapiens (Human) EMBL BAA25289.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	176 AA.
Sequence status	Fragment.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Hydrolase EMBL BAA25289.1 Kinase EMBL BAA25289.1 Transferase
Gene Ontology (GO)
Biological process	fructose 2,6-bisphosphate metabolic process Non-traceable author statement. Source: UniProtKB
Molecular function	6-phosphofructo-2-kinase activity Non-traceable author statement Ref.1. Source: UniProtKB ATP binding Inferred from electronic annotation. Source: InterPro fructose-2,6-bisphosphate 2-phosphatase activity Non-traceable author statement Ref.1. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAA25289.1

Sequences

	Sequence		Length	Mass (Da)
	O60352 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: EC03906F394D602D	FASTA	176	19,660
	10 20 30 40 50 60 CGPKLTNSPT VIVMVGLPAR GKTYISKKLT RYLNWIGVPT KVFNVGEYRR EAVKQYSSYN 70 80 90 100 110 120 FFRPDNEEAM KVRKQCALAA LRDVKSYLAK EGGQIAVFDA TNTTRERRHM ILHFAKENDF 130 140 150 160 170 KAFFIESVCD DPTVVASNIM VRQPGAPCFC GSVDHKGICS LRKWGTGSSS EAQLSP

References

[1]	"Cloning of cDNA encoding for a novel isozyme of fructose 6-phosphate, 2-kinase/fructose 2,6-bisphosphatase from human placenta." Sakai A., Kato M., Fukasawa M., Ishiguro M., Furuya E., Sakakibara R. J. Biochem. 119:506-511(1996) [PubMed: 8830046] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Placenta EMBL BAA25289.1.
[2]	Fukasawa M., Sakai A., Kato M., Ishiguro M., Furuya E., Sakakibara R. Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Placenta EMBL BAA25289.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB012229 Genomic DNA. Translation: BAA25289.1.
IPI	IPI00384559.
UniGene	Hs.195471.
3D structure databases
HSSP	HSSP built from PDB template 1K6M based on UniProtKB P16118.
ProteinModelPortal	O60352.
ModBase	Search...
Protein-protein interaction databases
STRING	O60352.
Proteomic databases
PRIDE	O60352.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG106284.
Family and domain databases
InterPro	IPR003094. 6Pfruct_kin. IPR013079. 6Phosfructo_kin. [Graphical view]
PANTHER	PTHR10606. 6Pfruct_kin. 1 hit.
Pfam	PF01591. 6PF2K. 1 hit. [Graphical view]
PRINTS	PR00991. 6PFRUCTKNASE.
ProtoNet	Search...

Entry information

Entry name

O60352_HUMAN

Accession

Primary (citable) accession number: O60352

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	August 1, 1998
Last modified:	January 11, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.