Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O60312

- AT10A_HUMAN

UniProt

O60312 - AT10A_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable phospholipid-transporting ATPase VA

Gene

ATP10A

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules Probable.Curated

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei427 – 42714-aspartylphosphate intermediateBy similarity
Metal bindingi1031 – 10311MagnesiumBy similarity
Metal bindingi1035 – 10351MagnesiumBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cation-transporting ATPase activity Source: InterPro
  3. magnesium ion binding Source: InterPro
  4. phospholipid-translocating ATPase activity Source: UniProtKB

GO - Biological processi

  1. ion transmembrane transport Source: Reactome
  2. phospholipid translocation Source: UniProtKB
  3. regulation of cell shape Source: UniProtKB
  4. transmembrane transport Source: Reactome
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Lipid transport, Transport

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_25149. Ion transport by P-type ATPases.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable phospholipid-transporting ATPase VA (EC:3.6.3.1)
Alternative name(s):
ATPase class V type 10A
Aminophospholipid translocase VA
P4-ATPase flippase complex alpha subunit ATP10A
Gene namesi
Name:ATP10A
Synonyms:ATP10C, ATPVA, ATPVC, KIAA0566
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 15

Organism-specific databases

HGNCiHGNC:13542. ATP10A.

Subcellular locationi

Cell membrane 1 Publication; Multi-pass membrane protein 1 Publication. Endoplasmic reticulum membrane 1 Publication
Note: Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not that of TMEM30B.

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB
  2. integral component of membrane Source: UniProtKB
  3. plasma membrane Source: Reactome
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Endoplasmic reticulum, Membrane

Pathology & Biotechi

Involvement in diseasei

Angelman syndrome (AS) [MIM:105830]: A neurodevelopmental disorder characterized by severe motor and intellectual retardation, ataxia, frequent jerky limb movements and flapping of the arms and hands, hypotonia, seizures, absence of speech, frequent smiling and episodes of paroxysmal laughter, open-mouthed expression revealing the tongue.
Note: The disease is caused by mutations affecting the gene represented in this entry.

Organism-specific databases

MIMi105830. phenotype.
Orphaneti72. Angelman syndrome.
PharmGKBiPA25097.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14991499Probable phospholipid-transporting ATPase VAPRO_0000046379Add
BLAST

Proteomic databases

PaxDbiO60312.
PRIDEiO60312.

PTM databases

PhosphoSiteiO60312.

Expressioni

Tissue specificityi

Widely expressed, with highest levels in kidney, followed by lung, brain, prostate, testis, ovary and small intestine.

Gene expression databases

BgeeiO60312.
CleanExiHS_ATP10A.
ExpressionAtlasiO60312. baseline and differential.
GenevestigatoriO60312.

Organism-specific databases

HPAiHPA041496.
HPA042509.

Interactioni

Subunit structurei

Component of a P4-ATPase flippase complex which consists of a catalytic alpha subunit and an accessory beta subunit.Curated

Protein-protein interaction databases

STRINGi9606.ENSP00000349325.

Structurei

3D structure databases

ProteinModelPortaliO60312.
SMRiO60312. Positions 1006-1066.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 8686CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini107 – 1104Exoplasmic loopSequence Analysis
Topological domaini129 – 309181CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini333 – 36230Exoplasmic loopSequence AnalysisAdd
BLAST
Topological domaini385 – 1087703CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini1109 – 111911Exoplasmic loopSequence AnalysisAdd
BLAST
Topological domaini1141 – 117030CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini1193 – 11997Exoplasmic loopSequence Analysis
Topological domaini1223 – 12286CytoplasmicSequence Analysis
Topological domaini1250 – 126718Exoplasmic loopSequence AnalysisAdd
BLAST
Topological domaini1293 – 1499207CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei87 – 10620HelicalSequence AnalysisAdd
BLAST
Transmembranei111 – 12818HelicalSequence AnalysisAdd
BLAST
Transmembranei310 – 33223HelicalSequence AnalysisAdd
BLAST
Transmembranei363 – 38422HelicalSequence AnalysisAdd
BLAST
Transmembranei1088 – 110821HelicalSequence AnalysisAdd
BLAST
Transmembranei1120 – 114021HelicalSequence AnalysisAdd
BLAST
Transmembranei1171 – 119222HelicalSequence AnalysisAdd
BLAST
Transmembranei1200 – 122223HelicalSequence AnalysisAdd
BLAST
Transmembranei1229 – 124921HelicalSequence AnalysisAdd
BLAST
Transmembranei1268 – 129225HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi467 – 4704Poly-Glu

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0474.
GeneTreeiENSGT00740000115303.
HOGENOMiHOG000202528.
HOVERGENiHBG107129.
InParanoidiO60312.
KOiK01530.
OMAiWRYQEKK.
OrthoDBiEOG76471S.
PhylomeDBiO60312.
TreeFamiTF354252.

Family and domain databases

Gene3Di2.70.150.10. 2 hits.
3.40.1110.10. 3 hits.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR006539. ATPase_P-typ_Plipid-transp.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
[Graphical view]
PANTHERiPTHR24092. PTHR24092. 1 hit.
PfamiPF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
PRINTSiPR00119. CATATPASE.
SUPFAMiSSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01652. ATPase-Plipid. 2 hits.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: O60312-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEREPAGTEE PGPPGRRRRR EGRTRTVRSN LLPPPGAEDP AAGAAKGERR
60 70 80 90 100
RRRGCAQHLA DNRLKTTKYT LLSFLPKNLF EQFHRPANVY FVFIALLNFV
110 120 130 140 150
PAVNAFQPGL ALAPVLFILA ITAFRDLWED YSRHRSDHKI NHLGCLVFSR
160 170 180 190 200
EEKKYVNRFW KEIHVGDFVR LRCNEIFPAD ILLLSSSDPD GLCHIETANL
210 220 230 240 250
DGETNLKRRQ VVRGFSELVS EFNPLTFTSV IECEKPNNDL SRFRGCIIHD
260 270 280 290 300
NGKKAGLYKE NLLLRGCTLR NTDAVVGIVI YAGHETKALL NNSGPRYKRS
310 320 330 340 350
KLERQMNCDV LWCVLLLVCM SLFSAVGHGL WIWRYQEKKS LFYVPKSDGS
360 370 380 390 400
SLSPVTAAVY SFLTMIIVLQ VLIPISLYVS IEIVKACQVY FINQDMQLYD
410 420 430 440 450
EETDSQLQCR ALNITEDLGQ IQYIFSDKTG TLTENKMVFR RCTVSGVEYS
460 470 480 490 500
HDANAQRLAR YQEADSEEEE VVPRGGSVSQ RGSIGSHQSV RVVHRTQSTK
510 520 530 540 550
SHRRTGSRAE AKRASMLSKH TAFSSPMEKD ITPDPKLLEK VSECDKSLAV
560 570 580 590 600
ARHQEHLLAH LSPELSDVFD FFIALTICNT VVVTSPDQPR TKVRVRFELK
610 620 630 640 650
SPVKTIEDFL RRFTPSCLTS GCSSIGSLAA NKSSHKLGSS FPSTPSSDGM
660 670 680 690 700
LLRLEERLGQ PTSAIASNGY SSQADNWASE LAQEQESERE LRYEAESPDE
710 720 730 740 750
AALVYAARAY NCVLVERLHD QVSVELPHLG RLTFELLHTL GFDSVRKRMS
760 770 780 790 800
VVIRHPLTDE INVYTKGADS VVMDLLQPCS SVDARGRHQK KIRSKTQNYL
810 820 830 840 850
NVYAAEGLRT LCIAKRVLSK EEYACWLQSH LEAESSLENS EELLFQSAIR
860 870 880 890 900
LETNLHLLGA TGIEDRLQDG VPETISKLRQ AGLQIWVLTG DKQETAVNIA
910 920 930 940 950
YACKLLDHDE EVITLNATSQ EACAALLDQC LCYVQSRGLQ RAPEKTKGKV
960 970 980 990 1000
SMRFSSLCPP STSTASGRRP SLVIDGRSLA YALEKNLEDK FLFLAKQCRS
1010 1020 1030 1040 1050
VLCCRSTPLQ KSMVVKLVRS KLKAMTLAIG DGANDVSMIQ VADVGVGISG
1060 1070 1080 1090 1100
QEGMQAVMAS DFAVPKFRYL ERLLILHGHW CYSRLANMVL YFFYKNTMFV
1110 1120 1130 1140 1150
GLLFWFQFFC GFSASTMIDQ WYLIFFNLLF SSLPPLVTGV LDRDVPANVL
1160 1170 1180 1190 1200
LTNPQLYKSG QNMEEYRPRT FWFNMADAAF QSLVCFSIPY LAYYDSNVDL
1210 1220 1230 1240 1250
FTWGTPIVTI ALLTFLLHLG IETKTWTWLN WITCGFSVLL FFTVALIYNA
1260 1270 1280 1290 1300
SCATCYPPSN PYWTMQALLG DPVFYLTCLM TPVAALLPRL FFRSLQGRVF
1310 1320 1330 1340 1350
PTQLQLARQL TRKSPRRCSA PKETFAQGRL PKDSGTEHSS GRTVKTSVPL
1360 1370 1380 1390 1400
SQPSWHTQQP VCSLEASGEP STVDMSMPVR EHTLLEGLSA PAPMSSAPGE
1410 1420 1430 1440 1450
AVLRSPGGCP EESKVRAAST GRVTPLSSLF SLPTFSLLNW ISSWSLVSRL
1460 1470 1480 1490
GSVLQFSRTE QLADGQAGRG LPVQPHSGRS GLQGPDHRLL IGASSRRSQ
Length:1,499
Mass (Da):167,688
Last modified:August 13, 2002 - v2
Checksum:iD4996A4D0635A68D
GO
Isoform 2 (identifier: O60312-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     150-155: REEKKY → SRSHLK
     156-1499: Missing.

Note: No experimental confirmation available.

Show »
Length:155
Mass (Da):17,610
Checksum:i687DF574B01D70F2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti388 – 3881Q → R in BAA25492. (PubMed:9628581)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti353 – 3531S → Y.
Corresponds to variant rs17116056 [ dbSNP | Ensembl ].
VAR_048380
Natural varianti504 – 5041R → H.
Corresponds to variant rs56724944 [ dbSNP | Ensembl ].
VAR_061038
Natural varianti532 – 5321T → M.
Corresponds to variant rs2066703 [ dbSNP | Ensembl ].
VAR_022004
Natural varianti784 – 7841A → T.
Corresponds to variant rs2066704 [ dbSNP | Ensembl ].
VAR_022005
Natural varianti834 – 8341E → K.
Corresponds to variant rs17555920 [ dbSNP | Ensembl ].
VAR_048381
Natural varianti1172 – 11721W → C.
Corresponds to variant rs2076742 [ dbSNP | Ensembl ].
VAR_022006
Natural varianti1179 – 11791A → T.
Corresponds to variant rs2076744 [ dbSNP | Ensembl ].
VAR_022007
Natural varianti1188 – 11881I → V.
Corresponds to variant rs2076745 [ dbSNP | Ensembl ].
VAR_022008
Natural varianti1198 – 11981V → M.
Corresponds to variant rs2076746 [ dbSNP | Ensembl ].
VAR_048382
Natural varianti1298 – 12981R → S.
Corresponds to variant rs3816800 [ dbSNP | Ensembl ].
VAR_022009
Natural varianti1397 – 13971A → V.
Corresponds to variant rs9324127 [ dbSNP | Ensembl ].
VAR_048383

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei150 – 1556REEKKY → SRSHLK in isoform 2. 1 PublicationVSP_056604
Alternative sequencei156 – 14991344Missing in isoform 2. 1 PublicationVSP_056605Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB051358 mRNA. Translation: BAB47392.1.
AY029504
, AY029487, AY029488, AY029489, AY029490, AY029491, AY029492, AY029493, AY029494, AY029495, AY029496, AY029497, AY029498, AY029499, AY029500, AY029501, AY029502, AY029503 Genomic DNA. Translation: AAK33100.1.
AC016266 Genomic DNA. No translation available.
AC023449 Genomic DNA. No translation available.
AC109512 Genomic DNA. No translation available.
BC052251 mRNA. Translation: AAH52251.1.
BC038712 mRNA. Translation: AAH38712.1.
AB011138 mRNA. Translation: BAA25492.1.
CCDSiCCDS32178.1. [O60312-1]
RefSeqiNP_077816.1. NM_024490.3.
XP_005268318.1. XM_005268261.2.
UniGeneiHs.659258.

Genome annotation databases

EnsembliENST00000356865; ENSP00000349325; ENSG00000206190. [O60312-1]
ENST00000389967; ENSP00000374617; ENSG00000206190. [O60312-2]
ENST00000619904; ENSP00000480665; ENSG00000206190. [O60312-2]
GeneIDi57194.
KEGGihsa:57194.
UCSCiuc010ayu.3. human. [O60312-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB051358 mRNA. Translation: BAB47392.1 .
AY029504
, AY029487 , AY029488 , AY029489 , AY029490 , AY029491 , AY029492 , AY029493 , AY029494 , AY029495 , AY029496 , AY029497 , AY029498 , AY029499 , AY029500 , AY029501 , AY029502 , AY029503 Genomic DNA. Translation: AAK33100.1 .
AC016266 Genomic DNA. No translation available.
AC023449 Genomic DNA. No translation available.
AC109512 Genomic DNA. No translation available.
BC052251 mRNA. Translation: AAH52251.1 .
BC038712 mRNA. Translation: AAH38712.1 .
AB011138 mRNA. Translation: BAA25492.1 .
CCDSi CCDS32178.1. [O60312-1 ]
RefSeqi NP_077816.1. NM_024490.3.
XP_005268318.1. XM_005268261.2.
UniGenei Hs.659258.

3D structure databases

ProteinModelPortali O60312.
SMRi O60312. Positions 1006-1066.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000349325.

PTM databases

PhosphoSitei O60312.

Proteomic databases

PaxDbi O60312.
PRIDEi O60312.

Protocols and materials databases

DNASUi 57194.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000356865 ; ENSP00000349325 ; ENSG00000206190 . [O60312-1 ]
ENST00000389967 ; ENSP00000374617 ; ENSG00000206190 . [O60312-2 ]
ENST00000619904 ; ENSP00000480665 ; ENSG00000206190 . [O60312-2 ]
GeneIDi 57194.
KEGGi hsa:57194.
UCSCi uc010ayu.3. human. [O60312-1 ]

Organism-specific databases

CTDi 57194.
GeneCardsi GC15M025923.
GeneReviewsi ATP10A.
HGNCi HGNC:13542. ATP10A.
HPAi HPA041496.
HPA042509.
MIMi 105830. phenotype.
605855. gene.
neXtProti NX_O60312.
Orphaneti 72. Angelman syndrome.
PharmGKBi PA25097.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0474.
GeneTreei ENSGT00740000115303.
HOGENOMi HOG000202528.
HOVERGENi HBG107129.
InParanoidi O60312.
KOi K01530.
OMAi WRYQEKK.
OrthoDBi EOG76471S.
PhylomeDBi O60312.
TreeFami TF354252.

Enzyme and pathway databases

Reactomei REACT_25149. Ion transport by P-type ATPases.

Miscellaneous databases

GeneWikii ATP10A.
GenomeRNAii 57194.
NextBioi 63284.
PROi O60312.
SOURCEi Search...

Gene expression databases

Bgeei O60312.
CleanExi HS_ATP10A.
ExpressionAtlasi O60312. baseline and differential.
Genevestigatori O60312.

Family and domain databases

Gene3Di 2.70.150.10. 2 hits.
3.40.1110.10. 3 hits.
3.40.50.1000. 2 hits.
InterProi IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR006539. ATPase_P-typ_Plipid-transp.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
[Graphical view ]
PANTHERi PTHR24092. PTHR24092. 1 hit.
Pfami PF00122. E1-E2_ATPase. 1 hit.
[Graphical view ]
PRINTSi PR00119. CATATPASE.
SUPFAMi SSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsi TIGR01652. ATPase-Plipid. 2 hits.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEi PS00154. ATPASE_E1_E2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A novel maternally expressed gene, ATP10C, encodes a putative aminophospholipid translocase associated with Angelman syndrome."
    Meguro M., Kashiwagi A., Mitsuya K., Nakao M., Kondo I., Saitoh S., Oshimura M.
    Nat. Genet. 28:19-20(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  2. "The human aminophospholipid-transporting ATPase gene ATP10C maps adjacent to UBE3A and exhibits similar imprinted expression."
    Herzing L.B.K., Kim S.-J., Cook E.H. Jr., Ledbetter D.H.
    Am. J. Hum. Genet. 68:1501-1505(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Analysis of the DNA sequence and duplication history of human chromosome 15."
    Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
    , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
    Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Tissue: Skin and Testis.
  5. "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
    Nagase T., Ishikawa K., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 337-1499 (ISOFORM 1).
    Tissue: Brain.
  6. "ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner."
    Takatsu H., Baba K., Shima T., Umino H., Kato U., Umeda M., Nakayama K., Shin H.W.
    J. Biol. Chem. 286:38159-38167(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.

Entry informationi

Entry nameiAT10A_HUMAN
AccessioniPrimary (citable) accession number: O60312
Secondary accession number(s): Q4G0S9, Q969I4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 13, 2002
Last modified: October 29, 2014
This is version 144 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3