Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O60242

- BAI3_HUMAN

UniProt

O60242 - BAI3_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Brain-specific angiogenesis inhibitor 3

Gene

BAI3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma.

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: GDB

GO - Biological processi

  1. G-protein coupled receptor signaling pathway Source: GDB
  2. negative regulation of angiogenesis Source: InterPro
  3. neuropeptide signaling pathway Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Protein family/group databases

MEROPSiS63.030.

Names & Taxonomyi

Protein namesi
Recommended name:
Brain-specific angiogenesis inhibitor 3
Gene namesi
Name:BAI3
Synonyms:KIAA0550
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 6

Organism-specific databases

HGNCiHGNC:945. BAI3.

Subcellular locationi

Cell membrane 2 Publications; Multi-pass membrane protein 2 Publications

GO - Cellular componenti

  1. integral component of membrane Source: GDB
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25249.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence AnalysisAdd
BLAST
Chaini25 – 15221498Brain-specific angiogenesis inhibitor 3PRO_0000012865Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi30 ↔ 55By similarity
Glycosylationi51 – 511N-linked (GlcNAc...)Sequence Analysis
Glycosylationi54 – 541N-linked (GlcNAc...)Sequence Analysis
Glycosylationi82 – 821N-linked (GlcNAc...)Sequence Analysis
Glycosylationi105 – 1051N-linked (GlcNAc...)Sequence Analysis
Glycosylationi241 – 2411N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi303 ↔ 336By similarity
Disulfide bondi307 ↔ 342By similarity
Disulfide bondi318 ↔ 326By similarity
Glycosylationi337 – 3371N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi357 ↔ 392By similarity
Disulfide bondi361 ↔ 397By similarity
Disulfide bondi372 ↔ 382By similarity
Disulfide bondi412 ↔ 447By similarity
Disulfide bondi416 ↔ 452By similarity
Glycosylationi418 – 4181N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi427 ↔ 437By similarity
Disulfide bondi467 ↔ 502By similarity
Disulfide bondi471 ↔ 507By similarity
Disulfide bondi482 ↔ 492By similarity
Disulfide bondi514 ↔ 5491 Publication
Disulfide bondi537 ↔ 5671 Publication
Glycosylationi540 – 5401N-linked (GlcNAc...)1 Publication
Modified residuei619 – 6191Phosphoserine1 Publication
Glycosylationi625 – 6251N-linked (GlcNAc...)1 Publication
Glycosylationi779 – 7791N-linked (GlcNAc...)Sequence Analysis
Glycosylationi812 – 8121N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi819 ↔ 8511 Publication
Glycosylationi828 – 8281N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi839 ↔ 8531 Publication
Glycosylationi937 – 9371N-linked (GlcNAc...)Sequence Analysis

Post-translational modificationi

The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. Does not undergo autocatalytic cleavage (in vitro).1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiO60242.
PRIDEiO60242.

PTM databases

PhosphoSiteiO60242.

Expressioni

Tissue specificityi

Strongly expressed in brain. Also detected in heart. Reduced expression is observed in some glioblastoma cell lines.

Gene expression databases

BgeeiO60242.
CleanExiHS_BAI3.
ExpressionAtlasiO60242. baseline and differential.
GenevestigatoriO60242.

Organism-specific databases

HPAiHPA015963.

Interactioni

Subunit structurei

Interacts with C1QL1, C1QL2, C1QL3 and C1QL4.1 Publication

Protein-protein interaction databases

BioGridi107053. 1 interaction.
DIPiDIP-56121N.
IntActiO60242. 1 interaction.
STRINGi9606.ENSP00000238918.

Structurei

Secondary structure

1
1522
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni519 – 5213
Beta strandi532 – 5354
Beta strandi541 – 55111
Beta strandi557 – 5593
Beta strandi563 – 5697
Helixi570 – 58314
Helixi589 – 60820
Helixi613 – 63220
Helixi639 – 65214
Helixi655 – 6573
Helixi658 – 6647
Turni665 – 6673
Helixi670 – 68718
Beta strandi694 – 6985
Beta strandi700 – 71011
Beta strandi718 – 7214
Helixi730 – 7345
Beta strandi738 – 7414
Helixi743 – 7464
Beta strandi759 – 76911
Helixi770 – 7723
Beta strandi781 – 7833
Beta strandi787 – 7948
Beta strandi803 – 8086
Beta strandi815 – 8239
Beta strandi833 – 8353
Beta strandi839 – 8457
Beta strandi848 – 8558
Beta strandi857 – 8648

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4DLOX-ray2.30A/B498-868[»]
ProteinModelPortaliO60242.
SMRiO60242. Positions 508-866.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini25 – 880856ExtracellularSequence AnalysisAdd
BLAST
Topological domaini902 – 9109CytoplasmicSequence Analysis
Topological domaini932 – 9398ExtracellularSequence Analysis
Topological domaini961 – 98121CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini1003 – 102321ExtracellularSequence AnalysisAdd
BLAST
Topological domaini1045 – 109854CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini1120 – 11256ExtracellularSequence Analysis
Topological domaini1147 – 1522376CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei881 – 90121Helical; Name=1Sequence AnalysisAdd
BLAST
Transmembranei911 – 93121Helical; Name=2Sequence AnalysisAdd
BLAST
Transmembranei940 – 96021Helical; Name=3Sequence AnalysisAdd
BLAST
Transmembranei982 – 100221Helical; Name=4Sequence AnalysisAdd
BLAST
Transmembranei1024 – 104421Helical; Name=5Sequence AnalysisAdd
BLAST
Transmembranei1099 – 111921Helical; Name=6Sequence AnalysisAdd
BLAST
Transmembranei1126 – 114621Helical; Name=7Sequence AnalysisAdd
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini30 – 159130CUBPROSITE-ProRule annotationAdd
BLAST
Domaini291 – 34353TSP type-1 1PROSITE-ProRule annotationAdd
BLAST
Domaini345 – 39854TSP type-1 2PROSITE-ProRule annotationAdd
BLAST
Domaini400 – 45354TSP type-1 3PROSITE-ProRule annotationAdd
BLAST
Domaini455 – 50854TSP type-1 4PROSITE-ProRule annotationAdd
BLAST
Domaini816 – 86853GPSPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi942 – 9454Poly-Thr
Compositional biasi1173 – 11764Poly-Ser

Sequence similaritiesi

Contains 1 CUB domain.PROSITE-ProRule annotation
Contains 1 GPS domain.PROSITE-ProRule annotation
Contains 4 TSP type-1 domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG146816.
GeneTreeiENSGT00760000119076.
HOGENOMiHOG000230916.
HOVERGENiHBG004813.
InParanoidiO60242.
KOiK04598.
OMAiWDDSKTN.
OrthoDBiEOG7KDF90.
PhylomeDBiO60242.
TreeFamiTF331634.

Family and domain databases

InterProiIPR000859. CUB_dom.
IPR022624. DUF3497.
IPR017981. GPCR_2-like.
IPR008077. GPCR_2_brain-spec_angio_inhib.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
IPR000884. Thrombospondin_1_rpt.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF12003. DUF3497. 1 hit.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF00090. TSP_1. 4 hits.
[Graphical view]
PRINTSiPR01694. BAIPRECURSOR.
PR00249. GPCRSECRETIN.
SMARTiSM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00209. TSP1. 4 hits.
[Graphical view]
SUPFAMiSSF82895. SSF82895. 4 hits.
PROSITEiPS01180. CUB. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS50092. TSP1. 4 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: O60242-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKAVRNLLIY IFSTYLLVMF GFNAAQDFWC STLVKGVIYG SYSVSEMFPK
60 70 80 90 100
NFTNCTWTLE NPDPTKYSIY LKFSKKDLSC SNFSLLAYQF DHFSHEKIKD
110 120 130 140 150
LLRKNHSIMQ LCNSKNAFVF LQYDKNFIQI RRVFPTNFPG LQKKGEEDQK
160 170 180 190 200
SFFEFLVLNK VSPSQFGCHV LCTWLESCLK SENGRTESCG IMYTKCTCPQ
210 220 230 240 250
HLGEWGIDDQ SLILLNNVVL PLNEQTEGCL TQELQTTQVC NLTREAKRPP
260 270 280 290 300
KEEFGMMGDH TIKSQRPRSV HEKRVPQEQA DAAKFMAQTG ESGVEEWSQW
310 320 330 340 350
STCSVTCGQG SQVRTRTCVS PYGTHCSGPL RESRVCNNTA LCPVHGVWEE
360 370 380 390 400
WSPWSLCSFT CGRGQRTRTR SCTPPQYGGR PCEGPETHHK PCNIALCPVD
410 420 430 440 450
GQWQEWSSWS QCSVTCSNGT QQRSRQCTAA AHGGSECRGP WAESRECYNP
460 470 480 490 500
ECTANGQWNQ WGHWSGCSKS CDGGWERRIR TCQGAVITGQ QCEGTGEEVR
510 520 530 540 550
RCNEQRCPAP YEICPEDYLM SMVWKRTPAG DLAFNQCPLN ATGTTSRRCS
560 570 580 590 600
LSLHGVAFWE QPSFARCISN EYRHLQHSIK EHLAKGQRML AGDGMSQVTK
610 620 630 640 650
TLLDLTQRKN FYAGDLLMSV EILRNVTDTF KRASYIPASD GVQNFFQIVS
660 670 680 690 700
NLLDEENKEK WEDAQQIYPG SIELMQVIED FIHIVGMGMM DFQNSYLMTG
710 720 730 740 750
NVVASIQKLP AASVLTDINF PMKGRKGMVD WARNSEDRVV IPKSIFTPVS
760 770 780 790 800
SKELDESSVF VLGAVLYKNL DLILPTLRNY TVINSKIIVV TIRPEPKTTD
810 820 830 840 850
SFLEIELAHL ANGTLNPYCV LWDDSKTNES LGTWSTQGCK TVLTDASHTK
860 870 880 890 900
CLCDRLSTFA ILAQQPREII MESSGTPSVT LIVGSGLSCL ALITLAVVYA
910 920 930 940 950
ALWRYIRSER SIILINFCLS IISSNILILV GQTQTHNKSI CTTTTAFLHF
960 970 980 990 1000
FFLASFCWVL TEAWQSYMAV TGKIRTRLIR KRFLCLGWGL PALVVATSVG
1010 1020 1030 1040 1050
FTRTKGYGTD HYCWLSLEGG LLYAFVGPAA AVVLVNMVIG ILVFNKLVSR
1060 1070 1080 1090 1100
DGILDKKLKH RAGQMSEPHS GLTLKCAKCG VVSTTALSAT TASNAMASLW
1110 1120 1130 1140 1150
SSCVVLPLLA LTWMSAVLAM TDKRSILFQI LFAVFDSLQG FVIVMVHCIL
1160 1170 1180 1190 1200
RREVQDAFRC RLRNCQDPIN ADSSSSFPNG HAQIMTDFEK DVDIACRSVL
1210 1220 1230 1240 1250
HKDIGPCRAA TITGTLSRIS LNDDEEEKGT NPEGLSYSTL PGNVISKVII
1260 1270 1280 1290 1300
QQPTGLHMPM SMNELSNPCL KKENSELRRT VYLCTDDNLR GADMDIVHPQ
1310 1320 1330 1340 1350
ERMMESDYIV MPRSSVNNQP SMKEESKMNI GMETLPHERL LHYKVNPEFN
1360 1370 1380 1390 1400
MNPPVMDQFN MNLEQHLAPQ EHMQNLPFEP RTAVKNFMAS ELDDNAGLSR
1410 1420 1430 1440 1450
SETGSTISMS SLERRKSRYS DLDFEKVMHT RKRHMELFQE LNQKFQTLDR
1460 1470 1480 1490 1500
FRDIPNTSSM ENPAPNKNPW DTFKNPSEYP HYTTINVLDT EAKDALELRP
1510 1520
AEWEKCLNLP LDVQEGDFQT EV
Length:1,522
Mass (Da):171,518
Last modified:November 2, 2010 - v2
Checksum:iD22D0A5CF59E811F
GO
Isoform 2 (identifier: O60242-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1036: Missing.

Note: No experimental confirmation available

Show »
Length:486
Mass (Da):55,035
Checksum:i361BC76A2B85A843
GO

Sequence cautioni

The sequence BAA25476.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti503 – 5031N → S.3 Publications
Corresponds to variant rs1932618 [ dbSNP | Ensembl ].
VAR_046525

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 10361036Missing in isoform 2. 1 PublicationVSP_056939Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB005299 mRNA. Translation: BAA25363.1.
AB011122 mRNA. Translation: BAA25476.2. Different initiation.
AK293560 mRNA. Translation: BAH11536.1.
AL035469 Genomic DNA. No translation available.
AL078598 Genomic DNA. No translation available.
AL589875 Genomic DNA. No translation available.
AL133378
, AL158051, AL160401, AL356117, AL359714, AL391807 Genomic DNA. Translation: CAC34969.2.
AL359714
, AL133378, AL158051, AL160401, AL356117, AL391807 Genomic DNA. Translation: CAH71522.1.
AL356117
, AL133378, AL158051, AL160401, AL359714, AL391807 Genomic DNA. Translation: CAH71772.1.
AL160401
, AL133378, AL158051, AL356117, AL359714, AL391807 Genomic DNA. Translation: CAH73864.1.
AL158051
, AL133378, AL160401, AL356117, AL359714, AL391807 Genomic DNA. Translation: CAI19625.1.
AL391807
, AL133378, AL158051, AL160401, AL356117, AL359714 Genomic DNA. Translation: CAI21673.1.
CH471051 Genomic DNA. Translation: EAW48837.1.
BC111720 mRNA. Translation: AAI11721.1.
CCDSiCCDS4968.1.
PIRiT00028.
T00326.
RefSeqiNP_001695.1. NM_001704.2.
XP_005248809.1. XM_005248752.1.
UniGeneiHs.13261.

Genome annotation databases

EnsembliENST00000370598; ENSP00000359630; ENSG00000135298.
ENST00000546190; ENSP00000441821; ENSG00000135298.
GeneIDi577.
KEGGihsa:577.
UCSCiuc003pev.4. human.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB005299 mRNA. Translation: BAA25363.1 .
AB011122 mRNA. Translation: BAA25476.2 . Different initiation.
AK293560 mRNA. Translation: BAH11536.1 .
AL035469 Genomic DNA. No translation available.
AL078598 Genomic DNA. No translation available.
AL589875 Genomic DNA. No translation available.
AL133378
, AL158051 , AL160401 , AL356117 , AL359714 , AL391807 Genomic DNA. Translation: CAC34969.2 .
AL359714
, AL133378 , AL158051 , AL160401 , AL356117 , AL391807 Genomic DNA. Translation: CAH71522.1 .
AL356117
, AL133378 , AL158051 , AL160401 , AL359714 , AL391807 Genomic DNA. Translation: CAH71772.1 .
AL160401
, AL133378 , AL158051 , AL356117 , AL359714 , AL391807 Genomic DNA. Translation: CAH73864.1 .
AL158051
, AL133378 , AL160401 , AL356117 , AL359714 , AL391807 Genomic DNA. Translation: CAI19625.1 .
AL391807
, AL133378 , AL158051 , AL160401 , AL356117 , AL359714 Genomic DNA. Translation: CAI21673.1 .
CH471051 Genomic DNA. Translation: EAW48837.1 .
BC111720 mRNA. Translation: AAI11721.1 .
CCDSi CCDS4968.1.
PIRi T00028.
T00326.
RefSeqi NP_001695.1. NM_001704.2.
XP_005248809.1. XM_005248752.1.
UniGenei Hs.13261.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4DLO X-ray 2.30 A/B 498-868 [» ]
ProteinModelPortali O60242.
SMRi O60242. Positions 508-866.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 107053. 1 interaction.
DIPi DIP-56121N.
IntActi O60242. 1 interaction.
STRINGi 9606.ENSP00000238918.

Protein family/group databases

MEROPSi S63.030.
GPCRDBi Search...

PTM databases

PhosphoSitei O60242.

Proteomic databases

PaxDbi O60242.
PRIDEi O60242.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000370598 ; ENSP00000359630 ; ENSG00000135298 .
ENST00000546190 ; ENSP00000441821 ; ENSG00000135298 .
GeneIDi 577.
KEGGi hsa:577.
UCSCi uc003pev.4. human.

Organism-specific databases

CTDi 577.
GeneCardsi GC06P069404.
HGNCi HGNC:945. BAI3.
HPAi HPA015963.
MIMi 602684. gene.
neXtProti NX_O60242.
PharmGKBi PA25249.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG146816.
GeneTreei ENSGT00760000119076.
HOGENOMi HOG000230916.
HOVERGENi HBG004813.
InParanoidi O60242.
KOi K04598.
OMAi WDDSKTN.
OrthoDBi EOG7KDF90.
PhylomeDBi O60242.
TreeFami TF331634.

Miscellaneous databases

ChiTaRSi BAI3. human.
GeneWikii Brain-specific_angiogenesis_inhibitor_3.
GenomeRNAii 577.
NextBioi 2355.
PROi O60242.
SOURCEi Search...

Gene expression databases

Bgeei O60242.
CleanExi HS_BAI3.
ExpressionAtlasi O60242. baseline and differential.
Genevestigatori O60242.

Family and domain databases

InterProi IPR000859. CUB_dom.
IPR022624. DUF3497.
IPR017981. GPCR_2-like.
IPR008077. GPCR_2_brain-spec_angio_inhib.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
IPR000203. GPS.
IPR000884. Thrombospondin_1_rpt.
[Graphical view ]
Pfami PF00002. 7tm_2. 1 hit.
PF12003. DUF3497. 1 hit.
PF01825. GPS. 1 hit.
PF02793. HRM. 1 hit.
PF00090. TSP_1. 4 hits.
[Graphical view ]
PRINTSi PR01694. BAIPRECURSOR.
PR00249. GPCRSECRETIN.
SMARTi SM00303. GPS. 1 hit.
SM00008. HormR. 1 hit.
SM00209. TSP1. 4 hits.
[Graphical view ]
SUPFAMi SSF82895. SSF82895. 4 hits.
PROSITEi PS01180. CUB. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
PS50092. TSP1. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1)."
    Shiratsuchi T., Nishimori H., Ichise H., Nakamura Y., Tokino T.
    Cytogenet. Cell Genet. 79:103-108(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT SER-503.
    Tissue: Fetal brain.
  2. "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
    Nagase T., Ishikawa K., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
    DNA Res. 5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT SER-503.
    Tissue: Brain.
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
    Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
    DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION TO 643-665 AND C-TERMINUS.
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Cerebellum.
  5. "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT SER-503.
  8. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-619, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. "The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins."
    Bolliger M.F., Martinelli D.C., Sudhof T.C.
    Proc. Natl. Acad. Sci. U.S.A. 108:2534-2539(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, INTERACTION WITH C1QL1; C1QL2; C1QL3 AND C1QL4.
  10. "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis."
    Arac D., Boucard A.A., Bolliger M.F., Nguyen J., Soltis S.M., Sudhof T.C., Brunger A.T.
    EMBO J. 31:1364-1378(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 498-868, PROTEOLYTIC PROCESSING, GLYCOSYLATION AT ASN-540 AND ASN-625, DISULFIDE BONDS, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiBAI3_HUMAN
AccessioniPrimary (citable) accession number: O60242
Secondary accession number(s): B7Z1K0
, O60297, Q2NKN6, Q5VY37, Q9BX54
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 2, 2010
Last modified: October 29, 2014
This is version 132 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  7. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3