Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

O60206 (XLNA_AGABI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endo-1,4-beta-xylanase

Short name=Xylanase
EC=3.2.1.8
Gene names
Name:xlnA
OrganismAgaricus bisporus (White button mushroom)
Taxonomic identifier5341 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesAgaricaceaeAgaricus

Protein attributes

Sequence length333 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Has xylanase activity. Seems to be involved in the release of sugars from the hemicellulolytic fraction in the compost.

Catalytic activity

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathway

Glycan degradation; xylan degradation.

Subcellular location

Secreted.

Induction

Repressed on glucose.

Sequence similarities

Belongs to the glycosyl hydrolase 10 (cellulase F) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Polysaccharide degradation
Xylan degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
Gene Ontology (GO)
   Biological_processxylan catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionendo-1,4-beta-xylanase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Potential
Chain18 – 333316Endo-1,4-beta-xylanase
PRO_0000007962

Sites

Active site1471Proton donor By similarity
Active site2521Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
O60206 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: CFAD93D81145E90A

FASTA33336,847
        10         20         30         40         50         60 
MYLVAFMLLA ILPTGYCQLN TLAVRAGKKY FGTATDNPEL GDAPYVAQLG NTADFNQITA 

        70         80         90        100        110        120 
GNSMKWDATE PSRGTFTFSN GDTVANMARN RGQLLRGHTC VWHSQLPNWV TSGNFDNSTL 

       130        140        150        160        170        180 
LSIVQNHCST LVSHYRGQMY SWDVVNEPFN EDGSFRQSVF FQKTGTAYIA TALRAARNAD 

       190        200        210        220        230        240 
PNTKLYINDF NIEGTGAKST GMINLVRSLQ QQNVPIDGIG VQAHLIVGQI PSSIQQNLQN 

       250        260        270        280        290        300 
FANLGVEVAI TELDIRMTLP VTQQKLEQQQ EDYRTVIRAC KAVSRCVGVT VWDWTDRYSW 

       310        320        330 
VPGVFNGEGA ACPWDENLAK KPAYQGIVDG WSQ 

« Hide

References

[1]"An endo-1,4-beta-xylanase-encoding gene from Agaricus bisporus is regulated by compost-specific factors."
De Groot P.W.J., Basten D.E.J.W., Sonnenberg A.S.M., van Griensven L.J.L.D., Visser J., Schaap P.J.
J. Mol. Biol. 277:273-284(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
Strain: Horst H39 and Horst U1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z83310 Genomic DNA. Translation: CAB05886.1.
Z83199 mRNA. Translation: CAB05665.1.

3D structure databases

ProteinModelPortalO60206.
SMRO60206. Positions 19-331.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH10. Glycoside Hydrolase Family 10.
mycoCLAPXYN10A_AGABI.

Proteomic databases

PRIDEO60206.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

OMAGFRPGLW.

Enzyme and pathway databases

UniPathwayUPA00114.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00331. Glyco_hydro_10. 1 hit.
[Graphical view]
PRINTSPR00134. GLHYDRLASE10.
SMARTSM00633. Glyco_10. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00591. GLYCOSYL_HYDROL_F10. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXLNA_AGABI
AccessionPrimary (citable) accession number: O60206
Entry history
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: August 1, 1998
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries