O60206 (XLNA_AGABI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Endo-1,4-beta-xylanase
Short name=Xylanase
EC=3.2.1.8

Gene names

Name:

xlnA

Organism

Agaricus bisporus (Common mushroom)

Taxonomic identifier

5341 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Homobasidiomycetes › Agaricomycetidae › Agaricales › Agaricaceae › Agaricus

Protein attributes

Sequence length	333 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Has xylanase activity. Seems to be involved in the release of sugars from the hemicellulolytic fraction in the compost.
Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Subcellular location	Secreted.
Induction	Repressed on glucose.
Sequence similarities	Belongs to the glycosyl hydrolase 10 (cellulase F) family.

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 17	17	Potential
	Chain	18 – 333	316	Endo-1,4-beta-xylanase		PRO_0000007962
Sites
	Active site	147	1	Proton donor By similarity
	Active site	252	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	O60206 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: CFAD93D81145E90A	FASTA	333	36,847
	10 20 30 40 50 60 MYLVAFMLLA ILPTGYCQLN TLAVRAGKKY FGTATDNPEL GDAPYVAQLG NTADFNQITA 70 80 90 100 110 120 GNSMKWDATE PSRGTFTFSN GDTVANMARN RGQLLRGHTC VWHSQLPNWV TSGNFDNSTL 130 140 150 160 170 180 LSIVQNHCST LVSHYRGQMY SWDVVNEPFN EDGSFRQSVF FQKTGTAYIA TALRAARNAD 190 200 210 220 230 240 PNTKLYINDF NIEGTGAKST GMINLVRSLQ QQNVPIDGIG VQAHLIVGQI PSSIQQNLQN 250 260 270 280 290 300 FANLGVEVAI TELDIRMTLP VTQQKLEQQQ EDYRTVIRAC KAVSRCVGVT VWDWTDRYSW 310 320 330 VPGVFNGEGA ACPWDENLAK KPAYQGIVDG WSQ

References

[1]	"An endo-1,4-beta-xylanase-encoding gene from Agaricus bisporus is regulated by compost-specific factors." De Groot P.W.J., Basten D.E.J.W., Sonnenberg A.S.M., van Griensven L.J.L.D., Visser J., Schaap P.J. J. Mol. Biol. 277:273-284(1998) [PubMed: 9514754] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. Strain: Horst H39 and Horst U1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z83310 Genomic DNA. Translation: CAB05886.1. Z83199 mRNA. Translation: CAB05665.1.
3D structure databases
ProteinModelPortal	O60206.
SMR	O60206. Positions 19-331.
ModBase	Search...
Protein family/group databases
CAZy	GH10. Glycoside Hydrolase Family 10.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
OMA	VEVAYTE.
Family and domain databases
InterPro	IPR001000. Glyco_hydro_10. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
Pfam	PF00331. Glyco_hydro_10. 1 hit. [Graphical view]
PRINTS	PR00134. GLHYDRLASE10.
SMART	SM00633. Glyco_10. 1 hit. [Graphical view]
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00591. GLYCOSYL_HYDROL_F10. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XLNA_AGABI

Accession

Primary (citable) accession number: O60206

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 17, 2003
Last sequence update:	August 1, 1998
Last modified:	September 21, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program