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Protein

U3 small nucleolar RNA-associated protein 10

Gene

utp10

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs). Involved in ribosome biosynthesis (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein
Biological processRibosome biogenesis, rRNA processing, Transcription

Enzyme and pathway databases

ReactomeiR-SPO-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Names & Taxonomyi

Protein namesi
Recommended name:
U3 small nucleolar RNA-associated protein 10
Short name:
U3 snoRNA-associated protein 10
Alternative name(s):
U3 protein 10 required for transcription
Gene namesi
Name:utp10
ORF Names:SPBC23E6.04c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC23E6.04c
PomBaseiSPBC23E6.04c utp10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001862061 – 1649U3 small nucleolar RNA-associated protein 10Add BLAST1649

Proteomic databases

MaxQBiO60179
PaxDbiO60179
PRIDEiO60179

PTM databases

iPTMnetiO60179

Interactioni

Subunit structurei

Component of the ribosomal small subunit (SSU) processome.By similarity

Protein-protein interaction databases

BioGridi276815, 3 interactors
STRINGi4896.SPBC23E6.04c.1

Structurei

3D structure databases

ProteinModelPortaliO60179
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati1608 – 1646HEATAdd BLAST39

Sequence similaritiesi

Belongs to the HEATR1/UTP10 family.Curated

Phylogenomic databases

InParanoidiO60179
KOiK14550
OMAiCFEHDQD
OrthoDBiEOG092C05B2
PhylomeDBiO60179

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR012954 BP28_C_dom
IPR021133 HEAT_type_2
IPR022125 U3snoRNP10
PfamiView protein in Pfam
PF08146 BP28CT, 1 hit
PF12397 U3snoRNP10, 1 hit
SMARTiView protein in SMART
SM01036 BP28CT, 1 hit
SUPFAMiSSF48371 SSF48371, 6 hits
PROSITEiView protein in PROSITE
PS50077 HEAT_REPEAT, 1 hit

Sequencei

Sequence statusi: Complete.

O60179-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSLQKQLK NIQSNNVLKI NKIRRAPSLL YDPKVAADMD LEEIYVTAVS
60 70 80 90 100
GFHELAVHEP RLLYFEKTLL GEQSVQVDRV LLNRTENEKI DLECVQILRL
110 120 130 140 150
LAPFFTEKNA LKVLEWLIRR FSIHEYVSDE FILSFLPFHD HPFFARILGC
160 170 180 190 200
SKPKSRPLLF LENAIKMPVT LSRADIVHAL SRDKEFFAMF AQFVQNTAES
210 220 230 240 250
HNMYPELARF WAGTMMEVLV AWHSSNEDPN VLLDRFFLRV SYAVSYVSSI
260 270 280 290 300
DFQIAGFMLL SSIAASLPLS PSIIPPLVSA ITDRLSFDNI KPALICVGHL
310 320 330 340 350
LQFCSSFEFD HEQLEKLESF GASSLLIELS QEHRLDEFFV SYWVSLIKSR
360 370 380 390 400
KQKDKKRLIS LLDTSISQIR VTHEQAKFLL SVIPVNQDFK ALQSYRRILD
410 420 430 440 450
SVIQPERKEG KLDNLINTLQ DKKKSSTFSK KDREVLLKKI SEIDSQTSFE
460 470 480 490 500
QCLAYADSAA DLDSSVFISL LSKFGDKIPF LLFCIANGSE RIIILSLIEL
510 520 530 540 550
RKTIEENKDV DYQIILPVVL YSLQSKDTEV RSRALNLILT FLELRNENLE
560 570 580 590 600
FSIIYGMDDN DNKNLRWLSP VETKYYCSDL LLDRSSEIGL DGTYLFSYIP
610 620 630 640 650
ERLFTEKKPK NASKEIAVTS FLSSHAACSK LSNVRVLLLE ILTRVHGKVE
660 670 680 690 700
DAKMQILLPR LEQLSEFNSE KFKTVSKREV EALVNCFNHT SFTSLLSFLS
710 720 730 740 750
SNIVLSQAIC RRIVEIQSHL KDPQRLEFVK AVISQDEQPH YYVDVLDSIK
760 770 780 790 800
IPDTVFKKLI GSVRLVKEKN PAIAKRKRID SHIFDGDVQR LTRILELLET
810 820 830 840 850
KNAASYPKLA SPLFEVLNSV IALKEDIVSS NYLLQLLLGL LYEMIGASPI
860 870 880 890 900
TELSPSIRID TLVGCIRSTN NPQIQNKALL LVSALANAAP EAVLHGVMPI
910 920 930 940 950
FTFMGSTVLS RDDAFSIHVI EQTVKTVISA LIRLGKDFDS SLLVSCFVNA
960 970 980 990 1000
FPHIPQHRRL RLYRLVLQTI GSNRFLSVVL IQFAEKMLLA KSTNVVAIHD
1010 1020 1030 1040 1050
FCLTLVQSFS VADRIGSINQ CSRFCLKSLE EQSNSDSNGK AVSLIKLDEL
1060 1070 1080 1090 1100
PMDVDLATLG SLRVKVLELI SLVSKAKNFA FDLAKIMENS VDSFVEIQAG
1110 1120 1130 1140 1150
LFESIKLLIT LSQQSSNEME LGHVYVALRS VIHLLPNELF CTVLGKLLHD
1160 1170 1180 1190 1200
ERALLRRKAL SIVQQRVQQG SKVSALTALI PDVTYNISNY SDEETTQLAM
1210 1220 1230 1240 1250
DCLAVMAKRF SASPELFISP IEVVSGPYGL KNSARDVQVS AIVCITVLTN
1260 1270 1280 1290 1300
TLAARILPYL ADIVNYSLSI LDDARKDPEG DLLELACFSM MIDFFKVLPE
1310 1320 1330 1340 1350
FSSSYVEPTI KCALASDRAF EHDAIGELLF ETIANFIPTR LLMKSIFAAW
1360 1370 1380 1390 1400
PECARLGSTA ALRLLELIEL ALQNSSRSAI GTVYKSIFKF FLDSFDSRRS
1410 1420 1430 1440 1450
LLFAEDVDNV ETQAVNVFLK FVMKLSDTTF RPLFLHLHSW ALEDLYETDP
1460 1470 1480 1490 1500
SGIVSRQTFF YNFLTIFLDT LKSIVTNYYA YVLDDTIELL SSKDTNSEVR
1510 1520 1530 1540 1550
HLVNSSLVSA FENDTEEFWM VPARFGKISP VLIEQIQYAP LLDDKVLVKA
1560 1570 1580 1590 1600
IVELASVASS SDNFRSMNTQ LLQYLRSSNI NARLLAIQIQ TQLYGRLGEN
1610 1620 1630 1640
WISTLPQSVP FIAELMEDDD DQVETATAEL VRIIDDRLGE NESLQDYLT
Length:1,649
Mass (Da):186,412
Last modified:August 1, 1998 - v1
Checksum:i6B4FD373125216D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA18872.1
PIRiT39938
RefSeqiNP_596604.1, NM_001022525.2

Genome annotation databases

EnsemblFungiiSPBC23E6.04c.1; SPBC23E6.04c.1:pep; SPBC23E6.04c
GeneIDi2540284
KEGGispo:SPBC23E6.04c

Similar proteinsi

Entry informationi

Entry nameiUTP10_SCHPO
AccessioniPrimary (citable) accession number: O60179
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: August 1, 1998
Last modified: March 28, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health