Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized ATP-dependent helicase C23E6.02

Gene

SPBC23E6.02

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi416 – 4238ATPPROSITE-ProRule annotation
Zinc fingeri746 – 79853RING-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • chromatin remodeling Source: PomBase
  • DNA duplex unwinding Source: GOC
  • DNA repair Source: PomBase
  • double-strand break repair via homologous recombination Source: PomBase
  • mitotic DNA replication maintenance of fidelity Source: PomBase
  • protein ubiquitination Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized ATP-dependent helicase C23E6.02 (EC:3.6.4.-)
Gene namesi
ORF Names:SPBC23E6.02
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC23E6.02.
PomBaseiSPBC23E6.02.

Subcellular locationi

GO - Cellular componenti

  • nuclear chromatin Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10401040Uncharacterized ATP-dependent helicase C23E6.02PRO_0000310787Add
BLAST

Proteomic databases

MaxQBiO60177.

Interactioni

Protein-protein interaction databases

BioGridi276992. 27 interactions.
MINTiMINT-4677828.

Structurei

3D structure databases

ProteinModelPortaliO60177.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini403 – 588186Helicase ATP-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini866 – 1032167Helicase C-terminalPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the SNF2/RAD54 helicase family.Curated
Contains 1 helicase ATP-binding domain.PROSITE-ProRule annotation
Contains 1 helicase C-terminal domain.PROSITE-ProRule annotation
Contains 1 RING-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri746 – 79853RING-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

InParanoidiO60177.
OMAiLMCANRS.
OrthoDBiEOG7N37N6.
PhylomeDBiO60177.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000330. SNF2_N.
IPR018957. Znf_C3HC4_RING-type.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PfamiPF00271. Helicase_C. 1 hit.
PF00176. SNF2_N. 1 hit.
PF00097. zf-C3HC4. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O60177-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNNTAFEQF TLNPCEQIPL DDKHNIGFNK NNTPDYSSSA SSDQLLKNDI
60 70 80 90 100
NRHEMERRIA FLNRKQALFN AFMHDSSSSL NTMESNIEKV NGLFPNDNSV
110 120 130 140 150
IALKPNEEKL NSSLSVENND STYTDATLIA PKIGLDRPNI NAITIDVDGH
160 170 180 190 200
SLQNEISSST DKLSPSQSDA LFEQKQDSLF WNDNAVIVVS DSESDDNNVR
210 220 230 240 250
TKSSLNDHDK VNMKEKRNLE LAFMNSKRKK LELPSLPVLS TAGPSYTNSL
260 270 280 290 300
ALPPFHHHNN YKMFNTTHTL EDDKFLQGKG TSNNPISLSD EEDNEINFQN
310 320 330 340 350
KRYGSDSVIL PGGLLHDSKL PEPGKHLFHL QWYHDRFHNI EGFNLSDSNN
360 370 380 390 400
QKVQDDQQQQ LEELFKDLDE QLVNDPTIRE GTPAGLIPTL MEHQKEGLMW
410 420 430 440 450
LKRLEESSKK GGILADDMGL GKTVQALALL VTRPPESKSV KTTLIITPVS
460 470 480 490 500
LLQQWHNEIL TKIAPSHRPT VYIHHGSSKK HKIAEQLMSY DIVLTTYNVI
510 520 530 540 550
AYEFKNKMAY DKSIEDNAPI KKFEHLPFFE AEWYRVILDE AQTIKNRNTL
560 570 580 590 600
AARGCCLLES TYRWCLSGTP MQNGVEEFYS LIKFLRIKPY SDWSSFSKDF
610 620 630 640 650
TIPLSSNINT SAPMKRFRGL LKAVLLRRTK NTKIDGKPIL TLPPKTAVKS
660 670 680 690 700
ETDLSSSEME FYNTLQSGAQ IQMRKYLQEG TITTHYGSLL VLLLRLRQAC
710 720 730 740 750
CHPWLIVARE AAVDDNDSFQ AKNRAIYNQI YPEAVNRLKL IETLQCSLCM
760 770 780 790 800
DVVAELLIIV PCGHFLCREC LTHVITSSED MAKQTSNENI SPKCSVCEEY
810 820 830 840 850
IDTERLLSYA LFRRYSGMAP IVDADNKLRT ENISELLPKQ YSNILENRQM
860 870 880 890 900
GMKIFTDPKH WTTSTKIEKA LNAVKEIIKK QPTDKILIFS QFVSFLELFT
910 920 930 940 950
VPFRQEGIKY LMYTGGLSTA ERNQALINFE VDPNVRVLLI SLKAGNVGLN
960 970 980 990 1000
LTCANHVIIL DPFWNPYIEE QAVDRAHRIG QDKPVNILRI VTNNTIEERV
1010 1020 1030 1040
LALQDRKREL IDSALGEKGL REISRLNTKE LSFLFGMSSR
Length:1,040
Mass (Da):118,365
Last modified:August 1, 1998 - v1
Checksum:iF5C7210283512470
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA18870.1.
PIRiT39936.
RefSeqiNP_596602.1. NM_001022523.2.

Genome annotation databases

EnsemblFungiiSPBC23E6.02.1; SPBC23E6.02.1:pep; SPBC23E6.02.
GeneIDi2540464.
KEGGispo:SPBC23E6.02.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA18870.1.
PIRiT39936.
RefSeqiNP_596602.1. NM_001022523.2.

3D structure databases

ProteinModelPortaliO60177.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276992. 27 interactions.
MINTiMINT-4677828.

Proteomic databases

MaxQBiO60177.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC23E6.02.1; SPBC23E6.02.1:pep; SPBC23E6.02.
GeneIDi2540464.
KEGGispo:SPBC23E6.02.

Organism-specific databases

EuPathDBiFungiDB:SPBC23E6.02.
PomBaseiSPBC23E6.02.

Phylogenomic databases

InParanoidiO60177.
OMAiLMCANRS.
OrthoDBiEOG7N37N6.
PhylomeDBiO60177.

Miscellaneous databases

PROiO60177.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000330. SNF2_N.
IPR018957. Znf_C3HC4_RING-type.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PfamiPF00271. Helicase_C. 1 hit.
PF00176. SNF2_N. 1 hit.
PF00097. zf-C3HC4. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYG42_SCHPO
AccessioniPrimary (citable) accession number: O60177
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: August 1, 1998
Last modified: June 8, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.