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O60172 (PPA3_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Thiamine-repressible acid phosphatase SPBC21H7.03c

EC=3.1.3.2
Gene names
ORF Names:SPBC21H7.03c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length463 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May dephosphorylate thiamine phosphates By similarity. UniProtKB Q01682

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate. UniProtKB Q01682

Subcellular location

Secretedcell wall By similarity UniProtKB Q01682.

Induction

Repressed by thiamine. Ref.2

Sequence similarities

Belongs to the histidine acid phosphatase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 463445Thiamine-repressible acid phosphatase SPBC21H7.03c
PRO_0000311718

Sites

Active site691Nucleophile By similarity UniProtKB P07102
Active site3411Proton donor By similarity UniProtKB P15309

Amino acid modifications

Glycosylation981N-linked (GlcNAc...) Potential
Glycosylation1041N-linked (GlcNAc...) Potential
Glycosylation2211N-linked (GlcNAc...) Potential
Glycosylation3241N-linked (GlcNAc...) Potential
Glycosylation4391N-linked (GlcNAc...) Potential
Glycosylation4581N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
O60172 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 6C41AF422C6D624A

FASTA46352,759
        10         20         30         40         50         60 
MQLCIISLWF LAAFIVNADN VQFEDYESNF FFKEHLGTLS PYHEPYFDGL DSAFPETCEI 

        70         80         90        100        110        120 
QQVHLLQRHG SRNPTGDVTA TDVYSSQYLN NFQEKLLNGS IPVNFSYPEN PLCFIKQWTP 

       130        140        150        160        170        180 
VIDAENADQL SSRGRLELFD LGRQLYQRYY KLFDSYVYDI NTAEQERVVE SAKWFTYGLF 

       190        200        210        220        230        240 
GDKMYEKTNF ILISEGKAAG ANSLSMYNAC PVFKDNNFHK NATDAAHAVW RNIFIEPIVN 

       250        260        270        280        290        300 
RLAKYFDSSY KLTINDVRSL FYICEYEIAI KDHSDFCSIF TPSEFLNFEY DSDLDQAYGG 

       310        320        330        340        350        360 
GPVSEWASTL GGAYINNLAD SLRNVTNPDF DRKVFLAFTH DSNIIPVEAA LGFFPDITPQ 

       370        380        390        400        410        420 
NPLPTDKNIY TYSQKTSSFV PFAGNLITEL FFCSDSKYYV RHLVNQQVYP LIDCGYGPSG 

       430        440        450        460 
TSDGLCELQA YLNSPIRANS TSNGISIFNT ECQARPTNVT IYF 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Activation of AP-1-dependent transcription by a truncated translation initiation factor."
Jenkins C.C.L., Mata J., Crane R.F., Thomas B., Akoulitchev A., Baehler J., Norbury C.J.
Eukaryot. Cell 4:1840-1850(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329671 Genomic DNA. Translation: CAA18863.1.
PIRT39929.
RefSeqNP_595928.1. NM_001021836.2.

3D structure databases

ProteinModelPortalO60172.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4896.SPBC21H7.03c-1.

Proteomic databases

MaxQBO60172.
PaxDbO60172.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPBC21H7.03c.1; SPBC21H7.03c.1:pep; SPBC21H7.03c.
GeneID2540420.
KEGGspo:SPBC21H7.03c.

Organism-specific databases

PomBaseSPBC21H7.03c.

Phylogenomic databases

eggNOGNOG260296.
HOGENOMHOG000115655.
KOK01078.
OMAVESAQWF.
OrthoDBEOG7B31X6.
PhylomeDBO60172.

Family and domain databases

Gene3D3.40.50.1240. 1 hit.
InterProIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
IPR016274. Histidine_acid_Pase_euk.
[Graphical view]
PfamPF00328. His_Phos_2. 1 hit.
[Graphical view]
PIRSFPIRSF000894. Acid_phosphatase. 1 hit.
SUPFAMSSF53254. SSF53254. 1 hit.
PROSITEPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20801547.
PROO60172.

Entry information

Entry namePPA3_SCHPO
AccessionPrimary (citable) accession number: O60172
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: August 1, 1998
Last modified: June 11, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names