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Protein

Thiamine-repressible acid phosphatase SPBC21H7.03c

Gene

SPBC21H7.03c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May dephosphorylate thiamine phosphates.By similarity

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei69NucleophileBy similarity1
Active sitei341Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Thiamine-repressible acid phosphatase SPBC21H7.03c (EC:3.1.3.2)
Gene namesi
ORF Names:SPBC21H7.03c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC21H7.03c
PomBaseiSPBC21H7.03c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000031171819 – 463Thiamine-repressible acid phosphatase SPBC21H7.03cAdd BLAST445

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi98N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi104N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi221N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi324N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi439N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi458N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiO60172
PaxDbiO60172
PRIDEiO60172

Expressioni

Inductioni

Repressed by thiamine.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi4896.SPBC21H7.03c.1

Structurei

3D structure databases

ProteinModelPortaliO60172
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.Sequence analysis

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000115655
InParanoidiO60172
KOiK01078
OMAiPVLRFYK
OrthoDBiEOG092C1SWD
PhylomeDBiO60172

Family and domain databases

CDDicd07061 HP_HAP_like, 1 hit
Gene3Di3.40.50.1240, 1 hit
InterProiView protein in InterPro
IPR033379 Acid_Pase_AS
IPR000560 His_Pase_clade-2
IPR029033 His_PPase_superfam
IPR016274 Histidine_acid_Pase_euk
PfamiView protein in Pfam
PF00328 His_Phos_2, 1 hit
PIRSFiPIRSF000894 Acid_phosphatase, 1 hit
SUPFAMiSSF53254 SSF53254, 1 hit
PROSITEiView protein in PROSITE
PS00616 HIS_ACID_PHOSPHAT_1, 1 hit
PS00778 HIS_ACID_PHOSPHAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O60172-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLCIISLWF LAAFIVNADN VQFEDYESNF FFKEHLGTLS PYHEPYFDGL
60 70 80 90 100
DSAFPETCEI QQVHLLQRHG SRNPTGDVTA TDVYSSQYLN NFQEKLLNGS
110 120 130 140 150
IPVNFSYPEN PLCFIKQWTP VIDAENADQL SSRGRLELFD LGRQLYQRYY
160 170 180 190 200
KLFDSYVYDI NTAEQERVVE SAKWFTYGLF GDKMYEKTNF ILISEGKAAG
210 220 230 240 250
ANSLSMYNAC PVFKDNNFHK NATDAAHAVW RNIFIEPIVN RLAKYFDSSY
260 270 280 290 300
KLTINDVRSL FYICEYEIAI KDHSDFCSIF TPSEFLNFEY DSDLDQAYGG
310 320 330 340 350
GPVSEWASTL GGAYINNLAD SLRNVTNPDF DRKVFLAFTH DSNIIPVEAA
360 370 380 390 400
LGFFPDITPQ NPLPTDKNIY TYSQKTSSFV PFAGNLITEL FFCSDSKYYV
410 420 430 440 450
RHLVNQQVYP LIDCGYGPSG TSDGLCELQA YLNSPIRANS TSNGISIFNT
460
ECQARPTNVT IYF
Length:463
Mass (Da):52,759
Last modified:August 1, 1998 - v1
Checksum:i6C41AF422C6D624A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA18863.1
PIRiT39929
RefSeqiNP_595928.1, NM_001021836.2

Genome annotation databases

EnsemblFungiiSPBC21H7.03c.1; SPBC21H7.03c.1:pep; SPBC21H7.03c
GeneIDi2540420
KEGGispo:SPBC21H7.03c

Similar proteinsi

Entry informationi

Entry nameiPPA3_SCHPO
AccessioniPrimary (citable) accession number: O60172
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: August 1, 1998
Last modified: March 28, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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