Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Septin homolog spn7

Gene

spn7

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Septin-like protein involved in the correct orientation of forespore membrane extension during sporulation. Binds phosphatidylinositol 4-phosphate.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei86 – 861GTP; via amide nitrogenBy similarity
Binding sitei224 – 2241GTP; via amide nitrogen and carbonyl oxygenBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi25 – 328GTPBy similarity
Nucleotide bindingi166 – 1749GTPBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Meiosis, Sporulation

Keywords - Ligandi

GTP-binding, Lipid-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Septin homolog spn7
Gene namesi
Name:spn7
ORF Names:SPBC19F8.01c, SPBC21.08c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC19F8.01c.
PomBaseiSPBC19F8.01c. spn7.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • membrane Source: UniProtKB-KW
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 428428Septin homolog spn7PRO_0000173509Add
BLAST

Proteomic databases

MaxQBiO60165.

Interactioni

Subunit structurei

Component of the sporulation-specific septin complex composed of at least spn2, spn5, spn6 and spn7.1 Publication

Protein-protein interaction databases

BioGridi276941. 5 interactions.
MINTiMINT-4677720.

Structurei

3D structure databases

ProteinModelPortaliO60165.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 290276Septin-type GAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000233586.
InParanoidiO60165.
KOiK16945.
OMAiSHERYEN.
OrthoDBiEOG76HQBH.
PhylomeDBiO60165.

Family and domain databases

InterProiIPR030379. G_SEPTIN_dom.
IPR016491. Septin.
[Graphical view]
PANTHERiPTHR18884. PTHR18884. 2 hits.
PfamiPF00735. Septin. 1 hit.
[Graphical view]
PIRSFiPIRSF006698. Septin. 1 hit.
PROSITEiPS51719. G_SEPTIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O60165-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKGPRHRPK FLSKKGKKLR IMVAGSSYTS YQACINSLCS KQILEAETEI
60 70 80 90 100
DPLKAHIDRI LEIREFNADI LEDEFHVDLT VIEVNGFGDK IDNSASFEVV
110 120 130 140 150
THYLESQFDQ ALIEESKIKR NSKFTDTRVD ALLYFIAPRG HCLSEFDLEA
160 170 180 190 200
MKRFSKRVNV IPVIGNSNAF TEEELKNFKD VIMKDLKQCN IKVFDFPWDP
210 220 230 240 250
EEDEDEVIED NKRLWESVPF AVSGGVSEED EEGYQRIVKK FQWGTFVIDD
260 270 280 290 300
PAHSDFLNLK TVLFISHLDI LKSITKQTYY ENYRTEKLSN DSPSNTSLSL
310 320 330 340 350
QKQNSIVANE DKRSVNGSER TETRSSIDQS EMRTNVSDST KSEELKKINS
360 370 380 390 400
IKVDNTSSLK CDSYGNTKTK TNQLNCEQIG LEVISPKEFP HRTTSSRNSL
410 420
PNNTTKELEM KKMDDLSHER YENLPFYR
Length:428
Mass (Da):49,298
Last modified:August 14, 2001 - v2
Checksum:iCD0B4E1D82DF41A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAD99124.1.
AF417166 mRNA. Translation: AAL13302.1.
PIRiT39824.
RefSeqiXP_001713143.1. XM_001713091.2.

Genome annotation databases

EnsemblFungiiSPBC19F8.01c.1; SPBC19F8.01c.1:pep; SPBC19F8.01c.
GeneIDi2540413.
KEGGispo:SPBC19F8.01c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAD99124.1.
AF417166 mRNA. Translation: AAL13302.1.
PIRiT39824.
RefSeqiXP_001713143.1. XM_001713091.2.

3D structure databases

ProteinModelPortaliO60165.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276941. 5 interactions.
MINTiMINT-4677720.

Proteomic databases

MaxQBiO60165.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC19F8.01c.1; SPBC19F8.01c.1:pep; SPBC19F8.01c.
GeneIDi2540413.
KEGGispo:SPBC19F8.01c.

Organism-specific databases

EuPathDBiFungiDB:SPBC19F8.01c.
PomBaseiSPBC19F8.01c. spn7.

Phylogenomic databases

HOGENOMiHOG000233586.
InParanoidiO60165.
KOiK16945.
OMAiSHERYEN.
OrthoDBiEOG76HQBH.
PhylomeDBiO60165.

Miscellaneous databases

PROiO60165.

Family and domain databases

InterProiIPR030379. G_SEPTIN_dom.
IPR016491. Septin.
[Graphical view]
PANTHERiPTHR18884. PTHR18884. 2 hits.
PfamiPF00735. Septin. 1 hit.
[Graphical view]
PIRSFiPIRSF006698. Septin. 1 hit.
PROSITEiPS51719. G_SEPTIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "Roles of septins in the fission yeast S. pombe."
    Wu J.-Q., Pringle J.R.
    Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 298-428.
  3. Wu J.-Q., Pringle J.R.
    Submitted (MAR-2001) to UniProtKB
    Cited for: CHARACTERIZATION.
  4. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. "Role of septins in the orientation of forespore membrane extension during sporulation in fission yeast."
    Onishi M., Koga T., Hirata A., Nakamura T., Asakawa H., Shimoda C., Bahler J., Wu J.Q., Takegawa K., Tachikawa H., Pringle J.R., Fukui Y.
    Mol. Cell. Biol. 30:2057-2074(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, IDENTIFICATION IN THE SPORULATION-SPECIFIC SEPTIN COMPLEX, PHOSPHATIDYLINOSITOL 4-PHOSPHATE-BINDING.

Entry informationi

Entry nameiSPN7_SCHPO
AccessioniPrimary (citable) accession number: O60165
Secondary accession number(s): O94648, Q7Z994, Q96US7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: August 14, 2001
Last modified: June 8, 2016
This is version 107 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.