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Protein

Septin homolog spn7

Gene

spn7

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Septin-like protein involved in the correct orientation of forespore membrane extension during sporulation. Binds phosphatidylinositol 4-phosphate.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei86GTP; via amide nitrogenBy similarity1
Binding sitei224GTP; via amide nitrogen and carbonyl oxygenBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi25 – 32GTPBy similarity8
Nucleotide bindingi166 – 174GTPBy similarity9

GO - Molecular functioni

GO - Biological processi

  • spore membrane bending pathway Source: PomBase

Keywordsi

Biological processMeiosis, Sporulation
LigandGTP-binding, Lipid-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Septin homolog spn7
Gene namesi
Name:spn7
ORF Names:SPBC19F8.01c, SPBC21.08c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC19F8.01c
PomBaseiSPBC19F8.01c spn7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001735091 – 428Septin homolog spn7Add BLAST428

Proteomic databases

MaxQBiO60165
PaxDbiO60165
PRIDEiO60165

PTM databases

iPTMnetiO60165

Interactioni

Subunit structurei

Component of the sporulation-specific septin complex composed of at least spn2, spn5, spn6 and spn7.1 Publication

Protein-protein interaction databases

BioGridi276941, 5 interactors
STRINGi4896.SPBC19F8.01c.1

Structurei

3D structure databases

ProteinModelPortaliO60165
SMRiO60165
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 290Septin-type GPROSITE-ProRule annotationAdd BLAST276

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni25 – 32G1 motifPROSITE-ProRule annotation8
Regioni83 – 86G3 motifPROSITE-ProRule annotation4
Regioni165 – 168G4 motifPROSITE-ProRule annotation4

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000233586
InParanoidiO60165
KOiK16945
OMAiEVENPHH
OrthoDBiEOG092C3HL6
PhylomeDBiO60165

Family and domain databases

InterProiView protein in InterPro
IPR030379 G_SEPTIN_dom
IPR016491 Septin
PfamiView protein in Pfam
PF00735 Septin, 1 hit
PIRSFiPIRSF006698 Septin, 1 hit
PROSITEiView protein in PROSITE
PS51719 G_SEPTIN, 1 hit

Sequencei

Sequence statusi: Complete.

O60165-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKGPRHRPK FLSKKGKKLR IMVAGSSYTS YQACINSLCS KQILEAETEI
60 70 80 90 100
DPLKAHIDRI LEIREFNADI LEDEFHVDLT VIEVNGFGDK IDNSASFEVV
110 120 130 140 150
THYLESQFDQ ALIEESKIKR NSKFTDTRVD ALLYFIAPRG HCLSEFDLEA
160 170 180 190 200
MKRFSKRVNV IPVIGNSNAF TEEELKNFKD VIMKDLKQCN IKVFDFPWDP
210 220 230 240 250
EEDEDEVIED NKRLWESVPF AVSGGVSEED EEGYQRIVKK FQWGTFVIDD
260 270 280 290 300
PAHSDFLNLK TVLFISHLDI LKSITKQTYY ENYRTEKLSN DSPSNTSLSL
310 320 330 340 350
QKQNSIVANE DKRSVNGSER TETRSSIDQS EMRTNVSDST KSEELKKINS
360 370 380 390 400
IKVDNTSSLK CDSYGNTKTK TNQLNCEQIG LEVISPKEFP HRTTSSRNSL
410 420
PNNTTKELEM KKMDDLSHER YENLPFYR
Length:428
Mass (Da):49,298
Last modified:August 14, 2001 - v2
Checksum:iCD0B4E1D82DF41A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAD99124.1
AF417166 mRNA Translation: AAL13302.1
PIRiT39824
RefSeqiXP_001713143.1, XM_001713091.2

Genome annotation databases

EnsemblFungiiSPBC19F8.01c.1; SPBC19F8.01c.1:pep; SPBC19F8.01c
KEGGispo:SPBC19F8.01c

Similar proteinsi

Entry informationi

Entry nameiSPN7_SCHPO
AccessioniPrimary (citable) accession number: O60165
Secondary accession number(s): O94648, Q7Z994, Q96US7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: August 14, 2001
Last modified: May 23, 2018
This is version 119 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health