Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Set1 complex component swd2

Gene

swd2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

The Set1 complex specifically methylates 'Lys-4' of histone H3.1 Publication

GO - Molecular functioni

GO - Biological processi

  • heterochromatin assembly involved in chromatin silencing Source: PomBase
  • histone H3-K4 methylation Source: PomBase
  • histone H3-K4 trimethylation Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Set1 complex component swd2
Short name:
Set1C component swd2
Alternative name(s):
COMPASS component swd2
Complex proteins associated with set1 protein swd2
Gene namesi
Name:swd2Imported
Synonyms:swd2.11 Publication
ORF Names:SPBC18H10.06c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC18H10.06c.
PomBaseiSPBC18H10.06c. swd2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000512521 – 357Set1 complex component swd2Add BLAST357

Proteomic databases

MaxQBiO60137.
PRIDEiO60137.

Interactioni

Subunit structurei

Component of the Set1 complex composed of ash2, sdc1, set1, shg1, spp1, swd1, swd2 and swd3.2 Publications

Protein-protein interaction databases

BioGridi277307. 176 interactors.
MINTiMINT-4677531.
STRINGi4896.SPBC18H10.06c.1.

Structurei

3D structure databases

ProteinModelPortaliO60137.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati24 – 65WD 1Sequence analysisAdd BLAST42
Repeati110 – 149WD 2Sequence analysisAdd BLAST40
Repeati199 – 241WD 3Sequence analysisAdd BLAST43
Repeati247 – 289WD 4Sequence analysisAdd BLAST43

Sequence similaritiesi

Belongs to the WD repeat SWD2 family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

HOGENOMiHOG000176477.
InParanoidiO60137.
KOiK14962.
OrthoDBiEOG092C3J3F.
PhylomeDBiO60137.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiView protein in InterPro
IPR015943. WD40/YVTN_repeat-like_dom_sf.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
IPR036322. WD40_repeat_dom_sf.
PfamiView protein in Pfam
PF00400. WD40. 1 hit.
SMARTiView protein in SMART
SM00320. WD40. 3 hits.
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiView protein in PROSITE
PS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

O60137-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTVSITFDL LSSMQPRKWL KNQNFVGEIT SLSFDDSGEL CLASCTDDTL
60 70 80 90 100
QLYNCISGKF VKSLASKKYG AHLGRFTHHS NSLIHASTKE DNTVRYLDVV
110 120 130 140 150
TNRYLRYFPG HKQTVTSIDV SPADETFLSA SLDNTIRLWD LRSPNCQGLL
160 170 180 190 200
NVSSPVVAAF DATGLIFASV SERKYKISLY NIKSFDARPF QDIPLTFLPP
210 220 230 240 250
HVRIANVEFS TDGKYLLLTT GNDFHYVIDA YSGSELLRVP SKVSTKTQDG
260 270 280 290 300
NLTYYASACM SPDSKFLFTS YDNEHLCMYQ LPELKQTVNS DHIVNSFTEM
310 320 330 340 350
GLASTTPTSN SHSTENPLAI IPSSTSKNLL PETPSIVRFN PRFSQLVTAH

SGVIFWT
Length:357
Mass (Da):39,813
Last modified:August 1, 1998 - v1
Checksum:iB7B901D7F3063C9D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA18403.1.
PIRiT39770.
RefSeqiNP_595730.1. NM_001021628.2.

Genome annotation databases

EnsemblFungiiSPBC18H10.06c.1; SPBC18H10.06c.1:pep; SPBC18H10.06c.
GeneIDi2540788.
KEGGispo:SPBC18H10.06c.

Similar proteinsi

Entry informationi

Entry nameiSWD2_SCHPO
AccessioniPrimary (citable) accession number: O60137
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: August 1, 1998
Last modified: November 22, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families