Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Translation initiation factor rli1

Gene

rli1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Component of the multifactor complex (MFC) involved in translation initiation. Required for the binding of MFC to the 40S ribosome. Required for the processing and nuclear export of the 60S and 40S ribosomal subunits (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi110 – 1178ATPPROSITE-ProRule annotation
Nucleotide bindingi382 – 3898ATPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis, Ribosome biogenesis, rRNA processing, Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor rli1
Alternative name(s):
ATP-binding cassette sub-family E member rli1
RNase L inhibitor
Gene namesi
Name:rli1
ORF Names:SPBC14F5.06
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC14F5.06.
PomBaseiSPBC14F5.06. rli1.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • cytosol Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 593593Translation initiation factor rli1PRO_0000316194Add
BLAST

Proteomic databases

MaxQBiO60102.

Interactioni

Subunit structurei

Component of the multifactor complex (MFC). The complex associates with preinitiation complexes (By similarity).By similarity

Protein-protein interaction databases

BioGridi276305. 1 interaction.
MINTiMINT-4677192.

Structurei

3D structure databases

ProteinModelPortaliO60102.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 39334Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd
BLAST
Domaini46 – 75304Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd
BLAST
Domaini70 – 318249ABC transporter 1PROSITE-ProRule annotationAdd
BLAST
Domaini334 – 556223ABC transporter 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated
Contains 2 4Fe-4S ferredoxin-type domains.PROSITE-ProRule annotation
Contains 2 ABC transporter domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000222803.
InParanoidiO60102.
KOiK06174.
OMAiAYKPQYI.
OrthoDBiEOG7G1VFV.
PhylomeDBiO60102.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013283. ABCE.
IPR027417. P-loop_NTPase.
IPR007209. RNaseL-inhib_metal-bd_dom.
[Graphical view]
PANTHERiPTHR19248. PTHR19248. 1 hit.
PfamiPF00005. ABC_tran. 2 hits.
PF00037. Fer4. 1 hit.
PF04068. RLI. 1 hit.
[Graphical view]
PRINTSiPR01868. ABCEFAMILY.
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O60102-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSESLTRIAI VSEDKCRPKK CRQECRRSCP VVRTGKLCIE VNPTDRIAFI
60 70 80 90 100
SETLCIGCGI CVKKCPFGAI NIINLPTNLE SEVTHRYSAN SFKLHRLPTP
110 120 130 140 150
RPGQVLGLVG TNGIGKSTAL KILSGKMKPN LGRYDNPPDW AEVVKYFRGS
160 170 180 190 200
ELQNFFTKVV EDNIKALIKP QYVDHIPRAI KTGDKTVSGL IKARANNNNF
210 220 230 240 250
EEVMDHTDLQ NLLNREVGHL SGGELQRFAI AAVATQKADV YMFDEPSSYL
260 270 280 290 300
DIKQRLKAGR VIRSLLATTN YVIVVEHDLS VLDYLSDFVC VLYGVPSMYG
310 320 330 340 350
VVTLPYSVRE GINIFLDGHI PTENLRFRSE ALTFRLADAS DEITADRTAE
360 370 380 390 400
YNYPDHVIEQ GDFKLTIKSG GFSDAEIIVL LGENGTGKTT FCKWMAKNSD
410 420 430 440 450
LKISMKPQTI APKFQGTVRM LFLKKIRAAF LNGKFQSEVC KPLSIDNIID
460 470 480 490 500
QEVLNLSGGE LQRVAICLAL GMPADVYLID EPSAYLDSEQ RIIASKVIRR
510 520 530 540 550
FIVNSRKTAF IVEHDFIMAT YLADRVILFE GQPSRDARCN PPQSLLTGMN
560 570 580 590
TFLKNLDVTF RRDPNTLRPR INKFDSQMDQ EQKNAGNYFF LEN
Length:593
Mass (Da):66,590
Last modified:August 1, 1998 - v1
Checksum:i20F2DBB5C02BB4D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA19324.1.
PIRiT39452.
RefSeqiNP_596732.1. NM_001022658.2.

Genome annotation databases

EnsemblFungiiSPBC14F5.06.1; SPBC14F5.06.1:pep; SPBC14F5.06.
GeneIDi2539753.
KEGGispo:SPBC14F5.06.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA19324.1.
PIRiT39452.
RefSeqiNP_596732.1. NM_001022658.2.

3D structure databases

ProteinModelPortaliO60102.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276305. 1 interaction.
MINTiMINT-4677192.

Proteomic databases

MaxQBiO60102.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC14F5.06.1; SPBC14F5.06.1:pep; SPBC14F5.06.
GeneIDi2539753.
KEGGispo:SPBC14F5.06.

Organism-specific databases

EuPathDBiFungiDB:SPBC14F5.06.
PomBaseiSPBC14F5.06. rli1.

Phylogenomic databases

HOGENOMiHOG000222803.
InParanoidiO60102.
KOiK06174.
OMAiAYKPQYI.
OrthoDBiEOG7G1VFV.
PhylomeDBiO60102.

Miscellaneous databases

PROiO60102.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013283. ABCE.
IPR027417. P-loop_NTPase.
IPR007209. RNaseL-inhib_metal-bd_dom.
[Graphical view]
PANTHERiPTHR19248. PTHR19248. 1 hit.
PfamiPF00005. ABC_tran. 2 hits.
PF00037. Fer4. 1 hit.
PF04068. RLI. 1 hit.
[Graphical view]
PRINTSiPR01868. ABCEFAMILY.
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRLI1_SCHPO
AccessioniPrimary (citable) accession number: O60102
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 1, 1998
Last modified: June 8, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.