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Protein

Translation initiation factor rli1

Gene

rli1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the multifactor complex (MFC) involved in translation initiation. Required for the binding of MFC to the 40S ribosome. Required for the processing and nuclear export of the 60S and 40S ribosomal subunits (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi110 – 117ATPPROSITE-ProRule annotation8
Nucleotide bindingi382 – 389ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis, Ribosome biogenesis, rRNA processing, Transport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor rli1
Alternative name(s):
ATP-binding cassette sub-family E member rli1
RNase L inhibitor
Gene namesi
Name:rli1
ORF Names:SPBC14F5.06
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC14F5.06
PomBaseiSPBC14F5.06 rli1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003161941 – 593Translation initiation factor rli1Add BLAST593

Proteomic databases

MaxQBiO60102
PaxDbiO60102
PRIDEiO60102

PTM databases

iPTMnetiO60102

Interactioni

Subunit structurei

Component of the multifactor complex (MFC). The complex associates with preinitiation complexes (By similarity).By similarity

Protein-protein interaction databases

BioGridi276305, 1 interactor
STRINGi4896.SPBC14F5.06.1

Structurei

3D structure databases

ProteinModelPortaliO60102
SMRiO60102
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 394Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd BLAST33
Domaini46 – 754Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd BLAST30
Domaini70 – 318ABC transporter 1PROSITE-ProRule annotationAdd BLAST249
Domaini334 – 556ABC transporter 2PROSITE-ProRule annotationAdd BLAST223

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000222803
InParanoidiO60102
KOiK06174
OMAiTGCNTFL
OrthoDBiEOG092C11NN
PhylomeDBiO60102

Family and domain databases

CDDicd03236 ABC_RNaseL_inhibitor_domain1, 1 hit
InterProiView protein in InterPro
IPR017896 4Fe4S_Fe-S-bd
IPR017900 4Fe4S_Fe_S_CS
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
IPR013283 RLI1
IPR034348 RLI_dom_1
IPR007209 RNaseL-inhib_metal-bd_dom
PANTHERiPTHR19248 PTHR19248, 1 hit
PfamiView protein in Pfam
PF00005 ABC_tran, 2 hits
PF00037 Fer4, 1 hit
PF04068 RLI, 1 hit
PRINTSiPR01868 ABCEFAMILY
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 3 hits
PROSITEiView protein in PROSITE
PS00198 4FE4S_FER_1, 1 hit
PS51379 4FE4S_FER_2, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

Sequencei

Sequence statusi: Complete.

O60102-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSESLTRIAI VSEDKCRPKK CRQECRRSCP VVRTGKLCIE VNPTDRIAFI
60 70 80 90 100
SETLCIGCGI CVKKCPFGAI NIINLPTNLE SEVTHRYSAN SFKLHRLPTP
110 120 130 140 150
RPGQVLGLVG TNGIGKSTAL KILSGKMKPN LGRYDNPPDW AEVVKYFRGS
160 170 180 190 200
ELQNFFTKVV EDNIKALIKP QYVDHIPRAI KTGDKTVSGL IKARANNNNF
210 220 230 240 250
EEVMDHTDLQ NLLNREVGHL SGGELQRFAI AAVATQKADV YMFDEPSSYL
260 270 280 290 300
DIKQRLKAGR VIRSLLATTN YVIVVEHDLS VLDYLSDFVC VLYGVPSMYG
310 320 330 340 350
VVTLPYSVRE GINIFLDGHI PTENLRFRSE ALTFRLADAS DEITADRTAE
360 370 380 390 400
YNYPDHVIEQ GDFKLTIKSG GFSDAEIIVL LGENGTGKTT FCKWMAKNSD
410 420 430 440 450
LKISMKPQTI APKFQGTVRM LFLKKIRAAF LNGKFQSEVC KPLSIDNIID
460 470 480 490 500
QEVLNLSGGE LQRVAICLAL GMPADVYLID EPSAYLDSEQ RIIASKVIRR
510 520 530 540 550
FIVNSRKTAF IVEHDFIMAT YLADRVILFE GQPSRDARCN PPQSLLTGMN
560 570 580 590
TFLKNLDVTF RRDPNTLRPR INKFDSQMDQ EQKNAGNYFF LEN
Length:593
Mass (Da):66,590
Last modified:August 1, 1998 - v1
Checksum:i20F2DBB5C02BB4D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA19324.1
PIRiT39452
RefSeqiNP_596732.1, NM_001022658.2

Genome annotation databases

EnsemblFungiiSPBC14F5.06.1; SPBC14F5.06.1:pep; SPBC14F5.06
GeneIDi2539753
KEGGispo:SPBC14F5.06

Similar proteinsi

Entry informationi

Entry nameiRLI1_SCHPO
AccessioniPrimary (citable) accession number: O60102
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: August 1, 1998
Last modified: March 28, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health