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O60087 (AMYG_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glucoamylase

EC=3.2.1.3
Alternative name(s):
1,4-alpha-D-glucan glucohydrolase
Glucan 1,4-alpha-glucosidase
Meiotic expression up-regulated protein 17
Gene names
Name:meu17
ORF Names:SPBC14C8.05c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.

Sequence similarities

Belongs to the glycosyl hydrolase 15 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1616 Potential
Propeptide17 – 2812 By similarity
PRO_0000001479
Chain29 – 450422Probable glucoamylase
PRO_0000001480

Sites

Active site2031Proton acceptor By similarity
Active site2061Proton donor By similarity
Binding site1471Substrate By similarity

Amino acid modifications

Glycosylation3831N-linked (GlcNAc...) Potential
Glycosylation4091N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
O60087 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 31C5BF2A8E4785FE

FASTA45051,164
        10         20         30         40         50         60 
MRTYWLFLLL GGVVSAESLL SPNKRSKEAS MDEWTDQQKG IAMGHMLNNI GDSGMHAKDI 

        70         80         90        100        110        120 
NPGCIIASPS TDSPDYYYQW VRDSALTIMT ILDRFFEGDK GLEPIIVKYM DEMVRLQKVP 

       130        140        150        160        170        180 
NPSGDFYAGG LGEPKFNVDG TSYDGDWGRP QNDSPALRAI AFIKYMNYLF ENGKEVHEVT 

       190        200        210        220        230        240 
VWIEAVLADL DYTANHWTEA SFDLWEEIKD VHYFTLAVQK RAMQDGTAFA KRIGAPDQAA 

       250        260        270        280        290        300 
LYQRTIEPID LKLGEFWDPG MGVIKGYKGR VDRSGLDCST LLASLYSNEF DMHILPTLLK 

       310        320        330        340        350        360 
LQETMTRDYP VNQGWKQAMG RYPEDVYDGV SKSIGNPWFI CTSSAAEIIY KAIAYYDNKG 

       370        380        390        400        410        420 
LPELTEYNIH FFMKFAEFGD PYNWSVIRKN MHTYADNFLK AVAEFQHPNG SMSEQFSRDD 

       430        440        450 
GHQKGARDLT WSYSSLLNAI YRREAIKGSV 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe."
Watanabe T., Miyashita K., Saito T.T., Yoneki T., Kakihara Y., Nabeshima K., Kishi Y.A., Shimoda C., Nojima H.
Nucleic Acids Res. 29:2327-2337(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 210-450.
Strain: CD16-1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329671 Genomic DNA. Translation: CAA18423.1.
AB054301 mRNA. Translation: BAB60870.1.
PIRT39433.
RefSeqNP_595908.1. NM_001021816.2.

3D structure databases

ProteinModelPortalO60087.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid276237. 1 interaction.
MINTMINT-4677080.
STRING4896.SPBC14C8.05c-1.

Protein family/group databases

CAZyGH15. Glycoside Hydrolase Family 15.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPBC14C8.05c.1; SPBC14C8.05c.1:pep; SPBC14C8.05c.
GeneID2539682.
KEGGspo:SPBC14C8.05c.

Organism-specific databases

PomBaseSPBC14C8.05c.

Phylogenomic databases

eggNOGCOG3387.
HOGENOMHOG000182646.
KOK01178.
OMAWIRDSAI.
OrthoDBEOG7NPG4B.
PhylomeDBO60087.

Family and domain databases

Gene3D1.50.10.10. 1 hit.
InterProIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR000165. Glucoamylase.
IPR011613. Glyco_hydro_15.
[Graphical view]
PfamPF00723. Glyco_hydro_15. 1 hit.
[Graphical view]
PRINTSPR00736. GLHYDRLASE15.
SUPFAMSSF48208. SSF48208. 1 hit.
ProtoNetSearch...

Other

NextBio20800836.

Entry information

Entry nameAMYG_SCHPO
AccessionPrimary (citable) accession number: O60087
Secondary accession number(s): Q96WS5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2002
Last sequence update: August 1, 1998
Last modified: May 14, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries