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Protein

Pumilio domain-containing protein C56F2.08c

Gene

SPBC56F2.08c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Pumilio domain-containing protein C56F2.08c
Gene namesi
ORF Names:SPBC56F2.08c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC56F2.08c.
PomBaseiSPBC56F2.08c.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 661661Pumilio domain-containing protein C56F2.08cPRO_0000310365Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei102 – 1021Phosphoserine1 Publication
Modified residuei104 – 1041Phosphothreonine1 Publication
Modified residuei105 – 1051Phosphoserine1 Publication
Modified residuei482 – 4821Phosphoserine1 Publication
Modified residuei486 – 4861Phosphoserine1 Publication
Modified residuei488 – 4881Phosphoserine1 Publication
Modified residuei490 – 4901Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO60059.

PTM databases

iPTMnetiO60059.

Interactioni

Protein-protein interaction databases

BioGridi277429. 181 interactions.
MINTiMINT-4676825.

Structurei

3D structure databases

ProteinModelPortaliO60059.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 7474RRMPROSITE-ProRule annotationAdd
BLAST
Domaini129 – 482354PUM-HDPROSITE-ProRule annotationAdd
BLAST
Repeati191 – 22636Pumilio 1Add
BLAST
Repeati227 – 26337Pumilio 2Add
BLAST
Repeati264 – 30239Pumilio 3Add
BLAST
Repeati374 – 41037Pumilio 4Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi482 – 596115Ser-richAdd
BLAST

Sequence similaritiesi

Contains 1 PUM-HD domain.PROSITE-ProRule annotation
Contains 4 pumilio repeats.PROSITE-ProRule annotation
Contains 1 RRM (RNA recognition motif) domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

InParanoidiO60059.
KOiK17974.
OMAiVLINIHA.
OrthoDBiEOG7SR4W6.
PhylomeDBiO60059.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
3.30.70.330. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR012677. Nucleotide-bd_a/b_plait.
IPR033133. PUM-HD.
IPR001313. Pumilio_RNA-bd_rpt.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00806. PUF. 1 hit.
PF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00025. Pumilio. 5 hits.
SM00360. RRM. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
SSF54928. SSF54928. 1 hit.
PROSITEiPS50302. PUM. 4 hits.
PS50303. PUM_HD. 1 hit.
PS50102. RRM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O60059-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYVSNLPVG TSSSAIHALF SAYGNVKDIW MLSPDNSAIV SYESLSSAIV
60 70 80 90 100
ARDALHNRPV FENHGPVQVM LAKPSSNYEP GNITAAVSPP ASTSSKDGVV
110 120 130 140 150
CSPTSTGASQ LLKSRVDILE VARQFEMRIN LDIVDSMIAS AIENNKVATE
160 170 180 190 200
ILPPVETLRS RQFEASKLRE IRKNIDSGFY TQEEIEVIAR SMLDDVAELS
210 220 230 240 250
SDYLGNTVVQ KFFEYCSDPI KEAMLERIAP YLAAIGIHKN GTWAAQKIID
260 270 280 290 300
VASTEKQMDL IVKHLRPYTA LLYFDQFGNY VAQCCLRFKY PKNTFLFEVM
310 320 330 340 350
ARHCCEIGQS RFGARAIRAC LENENATFEQ QALVVASIII NSHLLATNSN
360 370 380 390 400
GMLLLTWLLD NSFFRNRHRL LAIHLATHLH TTCTHKLAST LIFKLINNKQ
410 420 430 440 450
EPESRNLLLK NLFFSEKDNV LTYILQDQAV GPSFIHKVIT YPSIGREFLA
460 470 480 490 500
QFHLVIKRVL INIHAQPNAV YCRLMEEVGM TSKSISPSLS GISAPSASVD
510 520 530 540 550
SSASRLARDF GSLSLSSNSL LGSLGGLEST PAYPSYPSHI PLGTASLPLK
560 570 580 590 600
GNLYQISRSD DIKSGAPVLD TSSLVNPTLA KSASLNNSSL LNPSSSLLRR
610 620 630 640 650
EVPAGKLTMP AYPYTTQLMN HTAGADYGLP RLSSKLPQVF PGNYPRLQQS
660
LFPRQGELRF N
Length:661
Mass (Da):72,822
Last modified:August 1, 1998 - v1
Checksum:iACA0E4E4127ACBCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA18887.1.
PIRiT40536.
RefSeqiNP_596709.1. NM_001022634.2.

Genome annotation databases

EnsemblFungiiSPBC56F2.08c.1; SPBC56F2.08c.1:pep; SPBC56F2.08c.
GeneIDi2540913.
KEGGispo:SPBC56F2.08c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA18887.1.
PIRiT40536.
RefSeqiNP_596709.1. NM_001022634.2.

3D structure databases

ProteinModelPortaliO60059.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277429. 181 interactions.
MINTiMINT-4676825.

PTM databases

iPTMnetiO60059.

Proteomic databases

MaxQBiO60059.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC56F2.08c.1; SPBC56F2.08c.1:pep; SPBC56F2.08c.
GeneIDi2540913.
KEGGispo:SPBC56F2.08c.

Organism-specific databases

EuPathDBiFungiDB:SPBC56F2.08c.
PomBaseiSPBC56F2.08c.

Phylogenomic databases

InParanoidiO60059.
KOiK17974.
OMAiVLINIHA.
OrthoDBiEOG7SR4W6.
PhylomeDBiO60059.

Miscellaneous databases

NextBioi20802028.
PROiO60059.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
3.30.70.330. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR012677. Nucleotide-bd_a/b_plait.
IPR033133. PUM-HD.
IPR001313. Pumilio_RNA-bd_rpt.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00806. PUF. 1 hit.
PF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00025. Pumilio. 5 hits.
SM00360. RRM. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
SSF54928. SSF54928. 1 hit.
PROSITEiPS50302. PUM. 4 hits.
PS50303. PUM_HD. 1 hit.
PS50102. RRM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-102; THR-104; SER-105; SER-482; SER-486; SER-488 AND SER-490, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiYG58_SCHPO
AccessioniPrimary (citable) accession number: O60059
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: August 1, 1998
Last modified: April 13, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.