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Protein

Allergen Asp f 4

Gene

AFUA_2G03830

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • IgE binding Source: ASPGD
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Allergen Asp f 4
Alternative name(s):
Allergen: Asp f 4
Gene namesi
ORF Names:AFUA_2G03830
OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Taxonomic identifieri330879 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000002530 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiFungiDB:Afu2g03830.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Binds to IgE.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3122. Asp f 4.0101.
74. Asp f 4.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000004334121 – 322Allergen Asp f 4Add BLAST302

Interactioni

GO - Molecular functioni

  • IgE binding Source: ASPGD

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000178363.
InParanoidiO60024.
OMAiHERRHLH.
OrthoDBiEOG092C3SNW.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O60024-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLKNSMLLL TALAAGSSVA RLHGHERRHL HHAGEKREVG DTVYATINGV
60 70 80 90 100
LVSWINEWSG EAKTSDAPVS QATPVSNAVA AAAAASTPEP SSSHSDSSSS
110 120 130 140 150
SGVSADWTNT PAEGEYCTDG FGGRTEPSGS GIFYKGNVGK PWGSNIIEVS
160 170 180 190 200
PENAKKYKHV AQFVGSDTDP WTVVFWNKIG PDGGLTGWYG NSALTLHLEA
210 220 230 240 250
GETKYVAFDE NSQGAWGAAK GDELPKDQFG GYSCTWGEFD FDSKINQGWS
260 270 280 290 300
GWDVSAIQAE NAHHEVQGMK ICNHAGELCS IISHGLSKVI DAYTADLAGV
310 320
DGIGGKVVPG PTRLVVNLDY KE
Length:322
Mass (Da):34,085
Last modified:December 6, 2005 - v2
Checksum:i7EE283EB0E444EF0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti37R → G in CAA04959 (Ref. 2) Curated1
Sequence conflicti247Q → H in CAA04959 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000008 Genomic DNA. Translation: EAL87477.1.
AJ001732 mRNA. Translation: CAA04959.1.
RefSeqiXP_749515.1. XM_744422.1.

Genome annotation databases

EnsemblFungiiCADAFUAT00003407; CADAFUAP00003407; CADAFUAG00003407.
GeneIDi3506748.
KEGGiafm:AFUA_2G03830.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000008 Genomic DNA. Translation: EAL87477.1.
AJ001732 mRNA. Translation: CAA04959.1.
RefSeqiXP_749515.1. XM_744422.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3122. Asp f 4.0101.
74. Asp f 4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAFUAT00003407; CADAFUAP00003407; CADAFUAG00003407.
GeneIDi3506748.
KEGGiafm:AFUA_2G03830.

Organism-specific databases

EuPathDBiFungiDB:Afu2g03830.

Phylogenomic databases

HOGENOMiHOG000178363.
InParanoidiO60024.
OMAiHERRHLH.
OrthoDBiEOG092C3SNW.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiALL4_ASPFU
AccessioniPrimary (citable) accession number: O60024
Secondary accession number(s): Q4WHX8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: December 6, 2005
Last modified: September 7, 2016
This is version 65 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Allergens
    Nomenclature of allergens and list of entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.