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Protein

High-affinity hexose transporter ght4

Gene

ght4

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • glucose import Source: GO_Central
  • hexose transmembrane transport Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Sugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
High-affinity hexose transporter ght4
Short name:
Hexose transporter 4
Gene namesi
Name:ght4
ORF Names:SPBC1683.08
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC1683.08.
PomBaseiSPBC1683.08. ght4.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 9CytoplasmicSequence analysis9
Transmembranei10 – 30Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini31 – 58ExtracellularSequence analysisAdd BLAST28
Transmembranei59 – 79Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini80 – 87CytoplasmicSequence analysis8
Transmembranei88 – 108Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini109 – 112ExtracellularSequence analysis4
Transmembranei113 – 133Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini134 – 144CytoplasmicSequence analysisAdd BLAST11
Transmembranei145 – 165Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini166 – 179ExtracellularSequence analysisAdd BLAST14
Transmembranei180 – 200Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini201 – 266CytoplasmicSequence analysisAdd BLAST66
Transmembranei267 – 285Helical; Name=7Sequence analysisAdd BLAST19
Topological domaini286 – 301ExtracellularSequence analysisAdd BLAST16
Transmembranei302 – 322Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini323 – 328CytoplasmicSequence analysis6
Transmembranei329 – 349Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini350 – 363ExtracellularSequence analysisAdd BLAST14
Transmembranei364 – 384Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini385 – 404CytoplasmicSequence analysisAdd BLAST20
Transmembranei405 – 425Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini426 – 432ExtracellularSequence analysis7
Transmembranei433 – 453Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini454 – 557CytoplasmicSequence analysisAdd BLAST104

GO - Cellular componenti

  • integral component of plasma membrane Source: PomBase
  • plasma membrane Source: PomBase
  • plasma membrane of cell tip Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000504121 – 557High-affinity hexose transporter ght4Add BLAST557

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi357N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiO59932.

Interactioni

Protein-protein interaction databases

BioGridi276263. 7 interactors.
MINTiMINT-4676717.

Structurei

3D structure databases

ProteinModelPortaliO59932.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000202870.
InParanoidiO59932.
KOiK08139.
OrthoDBiEOG092C1Q5W.
PhylomeDBiO59932.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O59932-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRTLTSVLV VFISMAGWLG GADTGSISGI LGMRDFQSRF ADRYNPITNS
60 70 80 90 100
YSYSAWRQAL LTGTVNAGCL FGAMLSSPFT EAIGKKYSIA FFSGCYIIGQ
110 120 130 140 150
ILLVTAVPSW VQIMVGKLFT GLTIGALSVL SPGYQSEVAP PQIRGAVVST
160 170 180 190 200
YQLFQTCGTL IAACINMGTH KLRKTASWRT SFGINILWGI FLMVGVLFLP
210 220 230 240 250
ESPRYLIYKG RDEEALRIMC QTAELDPESE IIQTNFNTIK SDIEMEMAGG
260 270 280 290 300
KARWPEVFGK EVRYRTVLGF LTMLLRELIG NNYYFYYATQ VFKGTGMTDI
310 320 330 340 350
FLPAVILGAI NFGTTFGALY TIDNLGRRNP LIFGAAFQSI CFFIYAAVGD
360 370 380 390 400
RKLIYKNGTS DHRAGAVMIV FSCLFLFSYC CSWGPMGWVI VGETFPIRYR
410 420 430 440 450
SKCAAVATSG NWLGNFMVSF FTPFISNSIG FKLGYIYACI NMTSAFQIFL
460 470 480 490 500
MAKETKGLTL EEVNELYESD IKPWDSYKYV RQIESRRIHF SKEEEKRERE
510 520 530 540 550
KSKGYRGQEE RFIENADGAD NDDSSASSES FASAGAHSRS VFPRRSNVSE

ESHPTWV
Length:557
Mass (Da):62,126
Last modified:November 1, 1998 - v2
Checksum:i5777B64F76125D50
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051140 Genomic DNA. Translation: AAC63976.1.
CU329671 Genomic DNA. Translation: CAB91170.1.
PIRiT43657.
RefSeqiNP_595064.1. NM_001020970.2.

Genome annotation databases

EnsemblFungiiSPBC1683.08.1; SPBC1683.08.1:pep; SPBC1683.08.
GeneIDi2539710.
KEGGispo:SPBC1683.08.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051140 Genomic DNA. Translation: AAC63976.1.
CU329671 Genomic DNA. Translation: CAB91170.1.
PIRiT43657.
RefSeqiNP_595064.1. NM_001020970.2.

3D structure databases

ProteinModelPortaliO59932.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276263. 7 interactors.
MINTiMINT-4676717.

Proteomic databases

PRIDEiO59932.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC1683.08.1; SPBC1683.08.1:pep; SPBC1683.08.
GeneIDi2539710.
KEGGispo:SPBC1683.08.

Organism-specific databases

EuPathDBiFungiDB:SPBC1683.08.
PomBaseiSPBC1683.08. ght4.

Phylogenomic databases

HOGENOMiHOG000202870.
InParanoidiO59932.
KOiK08139.
OrthoDBiEOG092C1Q5W.
PhylomeDBiO59932.

Miscellaneous databases

PROiO59932.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport-like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGHT4_SCHPO
AccessioniPrimary (citable) accession number: O59932
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.