Reviewed, UniProtKB/Swiss-Prot O59859 (XYNA_ASPAC)

Names and origin

Protein names

Recommended name:
    Endo-1,4-beta-xylanase
      Short name=Xylanase
    EC=3.2.1.8
Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase
    FIA-xylanase

Gene names

Name:

xynIA

Organism

Aspergillus aculeatus

Taxonomic identifier

5053 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Subcellular location	Secreted By similarity.
Sequence similarities	Belongs to the glycosyl hydrolase 10 (cellulase F) family.

Ontologies

Keywords
Biological process	Xylan degradation
Cellular component	Secreted
Domain	Signal
Molecular function	Glycosidase Hydrolase
PTM	Disulfide bond Pyrrolidone carboxylic acid
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Potential
	Propeptide	20 – 25	6	Potential		PRO_0000007963
	Chain	26 – 327	302	Endo-1,4-beta-xylanase		PRO_0000007964
Sites
	Active site	157	1	Proton donor By similarity
	Active site	263	1	Nucleophile By similarity
Amino acid modifications
	Modified residue	26	1	Pyrrolidone carboxylic acid By similarity
	Disulfide bond	281 ↔ 287		By similarity

Sequences

	Sequence		Length	Mass (Da)
	O59859-1 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 4ED731EDB6FF0A74	FASTA	327	35,331
	10 20 30 40 50 60 MVQIKAAALA VLFASNVLAN PIEPRQASVS IDAKFKAHGK KYLGTIGDQY TLNKNAKTPA 70 80 90 100 110 120 IIKADFGQLT PENSMKWDAT EPNRGQFSFS GSDYLVNFAQ SNGKLIRGHT LVWHSQLPSW 130 140 150 160 170 180 VQSIYDKGTL IQVMQNHIAT VMQRYKGKVY AWDVVNEIFN EDGSLRQSHF YNVIGEDYVR 190 200 210 220 230 240 IAFETARAVD PNAKLYINDY NLDSASYPKL TGLVNHVKKW VAAGVPIDGI GSQTHLSAGA 250 260 270 280 290 300 GAAVSGALNA LAGAGTKEVA ITELDIAGAS STDYVNVVKA CLNQPKCVGI TVWGVADPDS 310 320 WRSSSSPLLF DSNYNPKAAY TAIANAL

References

[1]	Arai M., Kawaguchi T., Sumitani J. Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB013110 Genomic DNA. Translation: BAA25847.1.
3D structure databases
HSSP	HSSP built from PDB template 1B31 based on UniProtKB P56588.
SMR	O59859. Positions 26-327.
ModBase	Search...
Protein family/group databases
CAZy	GH10. Glycoside Hydrolase Family 10.
Enzyme and pathway databases
BRENDA	3.2.1.8. 97085.
Family and domain databases
InterPro	IPR001000. Glyco_hydro_10. IPR013781. Glyco_hydro_sg_catalytic. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
Pfam	PF00331. Glyco_hydro_10. 1 hit. [Graphical view]
PRINTS	PR00134. GLHYDRLASE10.
SMART	SM00633. Glyco_10. 1 hit. [Graphical view]
PROSITE	PS00591. GLYCOSYL_HYDROL_F10. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYNA_ASPAC

Accession

Primary (citable) accession number: O59859

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	August 1, 1998
Last modified:	June 16, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)