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O59832 (DPEH2_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized dipeptidase C965.12
EC=3.4.13.19
Gene names
ORF Names:SPCC965.12
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces ›

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of dipeptides.

Cofactor

Zinc By similarity.

Sequence similarities

Belongs to the peptidase M19 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416Uncharacterized dipeptidase C965.12
PRO_0000314655

Sites

Metal binding291Zinc 1; catalytic By similarity
Metal binding311Zinc 1; catalytic By similarity
Metal binding1441Zinc 1; catalytic By similarity
Metal binding1441Zinc 2; catalytic By similarity
Metal binding2151Zinc 2; catalytic By similarity
Metal binding2361Zinc 2; catalytic By similarity

Sequences

Sequence LengthMass (Da)Tools
O59832 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 8EB843F4C662D625

FASTA41647,421
        10         20         30         40         50         60 
MTVDLREEKE LAQQRFKEIC KHAKIVDTHN DFPYLLRVQL RNKLQLAEFD FENGLTSHTD 

        70         80         90        100        110        120 
LVKMRQGQVG VQFFSCFIEC KNPNYLYQDF DTPTTVVRDT LEQIDVTRRL VCKYNNDLKF 

       130        140        150        160        170        180 
VDCADDAIAA FRNNGKIAIA LGVEGLHQVD TSLAVLRQYY SLGVRYITLT HNCDNPFATA 

       190        200        210        220        230        240 
ASSITGGLPD RGLSAYGIEC IFEMNRLGMM VDLSHVSHRT MHDALDVTKA PVIFSHSSAY 

       250        260        270        280        290        300 
TLTEHERNVR DDVLERLKTN GGVVQVNFYQ DFIRKPGSDR ATIDDAADHI LHIIKVAGWE 

       310        320        330        340        350        360 
HVGLGSDFDG IPQGPKGLED VSKYPDLICK IIERTNATNE QIEGLMGLNV LRVWKKTELV 

       370        380        390        400        410 
ALQLSKKLEP IESSWSGRKW EFYSYAKEFP ELFPDAYKLN EKSTVWNYDQ PLNIEK

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU329672 Genomic DNA. Translation: CAA19072.1.
RefSeqNP_588522.1. NM_001023511.2.

3D structure databases

HSSPHSSP built from PDB template 1ITU based on UniProtKB P16444.
ProteinModelPortalO59832.
ModBaseSearch...

Protein-protein interaction databases

STRING4896.SPCC965.12-1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPCC965.12.1; SPCC965.12.1:pep; SPCC965.12.
GeneID2539107.
KEGGspo:SPCC965.12.

Organism-specific databases

PomBaseSPCC965.12.

Phylogenomic databases

eggNOGCOG2355.
HOGENOMHOG000072016.
KOK01273.
OMACKNARNV.
OrthoDBEOG4T7CBW.

Family and domain databases

InterProIPR008257. Peptidase_M19.
[Graphical view]
PANTHERPTHR10443. PTHR10443. 1 hit.
PfamPF01244. Peptidase_M19. 1 hit.
[Graphical view]
PROSITEPS00869. RENAL_DIPEPTIDASE_1. False negative.
PS51365. RENAL_DIPEPTIDASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20800279.

Entry information

Entry nameDPEH2_SCHPO
AccessionPrimary (citable) accession number: O59832
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 1, 1998
Last modified: April 3, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

Peptidase families

Classification of peptidase families and list of entries

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents