Reviewed,
UniProtKB/Swiss-Prot O59827 (GST2_SCHPO)
Last modified
November 3, 2009.
Version 59.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: Glutathione S-transferase 2 EC=2.5.1.18 Alternative name(s): GST-II | ||||
| Gene names |
| ||||
| Organism | Schizosaccharomyces pombe (Fission yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4896 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces |
Protein attributes
| Sequence length | 230 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Involved in the oxidative stress response and detoxification. Ref.1 |
| Catalytic activity | RX + glutathione = HX + R-S-glutathione. |
| Induction | By O-dinitrobenzene. Ref.1 |
| Sequence similarities | Belongs to the GST superfamily. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cellular response to oxidative stress Ref.1 Traceable author statement. Source: GeneDB_SPombe |
| Cellular component | cytosol Inferred from direct assay. Source: GeneDB_SPombe nucleusInferred from direct assay. Source: GeneDB_SPombe |
| Molecular function | glutathione transferase activity Ref.1 Inferred from direct assay. Source: GeneDB_SPombe protein heterodimerization activityInferred from physical interaction. Source: GeneDB_SPombe protein homodimerization activityInferred from physical interaction. Source: GeneDB_SPombe |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "A second stress-inducible glutathione S-transferase gene from Schizosaccharomyces pombe." Cho Y.-W., Park E.-H., Fuchs J.A., Lim C.-J. Biochim. Biophys. Acta 1574:399-402(2002) [PubMed: 11997110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, INDUCTION. |
| [2] | "The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. Nurse P.Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972. |
Cross-references
Sequence databases | |
|---|---|
| AF395117 Genomic DNA. Translation: AAK77864.1. CU329672 Genomic DNA. Translation: CAA19067.1. | |
| PIR | T41660. |
| RefSeq | NP_588517.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1K0D based on UniProtKB P23202. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | O59827. |
Genome annotation databases | |
| GeneID | 2539601. |
| GenomeReviews | Gene locus gst2 in contig CU329672_GR. |
| KEGG | spo:SPCC965.07c. |
| NMPDR | fig|4896.1.peg.855. |
Organism-specific databases | |
| GeneDB_Spombe | SPCC965.07c. |
Phylogenomic databases | |
| OMA | NTDLTLW. |
Enzyme and pathway databases | |
| BioCyc | SPOM-XXX-01:SPOM-XXX-01-000418-MON. |
| BRENDA | 2.5.1.18. 653. |
Gene expression databases | |
| ArrayExpress | O59827. |
Family and domain databases | |
| InterPro | IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012335. Thioredoxin_fold. [Graphical view] |
| Gene3D | G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. |
| Pfam | PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view] |
| PROSITE | PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | GST2_SCHPO | ||||||||
| Accession | Primary (citable) accession number: O59827 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


