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O59819 (UGPA2_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable UTP--glucose-1-phosphate uridylyltransferase

EC=2.7.7.9
Alternative name(s):
UDP-glucose pyrophosphorylase
Short name=UDPGP
Short name=UGPase
Gene names
ORF Names:SPCC794.10
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length499 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Plays a central role as a glucosyl donor in cellular metabolic pathways By similarity.

Catalytic activity

UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.

Subcellular location

Cytoplasm. Nucleus Ref.2 Ref.3.

Sequence similarities

Belongs to the UDPGP type 1 family.

Ontologies

Keywords
   Cellular componentCytoplasm
Nucleus
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processUDP-glucose metabolic process

Inferred from sequence orthology. Source: PomBase

   Cellular_componentcytoplasm

Inferred from sequence orthology. Source: PomBase

cytosol

Inferred from direct assay Ref.3. Source: PomBase

nucleus

Inferred from direct assay Ref.3. Source: PomBase

   Molecular_functionnucleotidyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 499499Probable UTP--glucose-1-phosphate uridylyltransferase
PRO_0000185764

Sequences

Sequence LengthMass (Da)Tools
O59819 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 8DE4ABC3EC212A60

FASTA49956,740
        10         20         30         40         50         60 
MLHRRIHFKS QSTLDFDSVA VSISASTMKN ELDKLVLNSR VSDKKTFGIQ MDNFFALYRR 

        70         80         90        100        110        120 
YLLHTVKGYE CDWDSIRPLG PEDMIDYGDL PLCKNAGKYL NRLAVVKLNG GMGNALGVNY 

       130        140        150        160        170        180 
PKAMIEVRDN QSFLDLSIRQ IEYLNRRYDV SVPFILMNSY DTNDETCKVL RKYAGCKIDI 

       190        200        210        220        230        240 
STFEQSRYPR VFVDSQLPVP KAAPSPIEEW YPPGHGDIFD ALVHSGTIER LLAQGKDYLF 

       250        260        270        280        290        300 
VSNIDNLGAS VDLNILSHVI DNQIEYSMEI TDKTKADIKV GILVNQDGLL RLLETNQVPE 

       310        320        330        340        350        360 
QHREEFMSDK VFKYINTNNV WLYLPAVKRV VENRELNLDI MPNIETVYYN NEPARIIEFT 

       370        380        390        400        410        420 
TAIGSAISQF KKTEGIRVSR PRFISVKNSS DLFLVRCDLY NVDHGSLKIE ESRLGFPPPV 

       430        440        450        460        470        480 
VRMSNEFKDI AELFCRIPYM PSMKDLVSLS ISGNVYFGRN VILKGNIVIV ASENTILCIP 

       490 
SNAVLENCVV TGNCKIMEC 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library."
Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T., Hiraoka Y.
Genes Cells 5:169-190(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 44-252, SUBCELLULAR LOCATION.
Strain: ATCC 38364 / 968.
[3]"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329672 Genomic DNA. Translation: CAA19137.1.
AB027910 Genomic DNA. Translation: BAA87214.1.
PIRT41618.
RefSeqNP_587758.1. NM_001022751.2.

3D structure databases

ProteinModelPortalO59819.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

MINTMINT-4676422.
STRING4896.SPCC794.10-1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPCC794.10.1; SPCC794.10.1:pep; SPCC794.10.
GeneID2539585.
KEGGspo:SPCC794.10.

Organism-specific databases

PomBaseSPCC794.10.

Phylogenomic databases

HOGENOMHOG000113618.
KOK00963.
OrthoDBEOG7KDFKX.
PhylomeDBO59819.

Family and domain databases

InterProIPR002618. UDPGP_trans.
IPR016267. UDPGP_trans_subgr.
[Graphical view]
PANTHERPTHR11952. PTHR11952. 1 hit.
PTHR11952:SF1. PTHR11952:SF1. 1 hit.
PfamPF01704. UDPGP. 1 hit.
[Graphical view]
PIRSFPIRSF000806. UDPGP. 1 hit.
ProtoNetSearch...

Other

NextBio20800743.

Entry information

Entry nameUGPA2_SCHPO
AccessionPrimary (citable) accession number: O59819
Secondary accession number(s): Q9UTZ5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: August 1, 1998
Last modified: April 16, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names