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Protein

Probable importin c550.11

Gene

SPCC550.11

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Active in protein import into the nucleus.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-SPO-5578749. Transcriptional regulation by small RNAs.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable importin c550.11
Gene namesi
ORF Names:SPCC550.11
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC550.11.
PomBaseiSPCC550.11.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • cytosol Source: PomBase
  • nuclear envelope Source: PomBase
  • nuclear pore Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10291029Probable importin c550.11PRO_0000303894Add
BLAST

Proteomic databases

MaxQBiO59809.

Interactioni

Protein-protein interaction databases

BioGridi276026. 52 interactions.
MINTiMINT-4676350.

Structurei

3D structure databases

ProteinModelPortaliO59809.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini21 – 9777Importin N-terminalPROSITE-ProRule annotationAdd
BLAST
Repeati506 – 54439HEATAdd
BLAST

Sequence similaritiesi

Contains 1 HEAT repeat.Curated
Contains 1 importin N-terminal domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000163050.
InParanoidiO59809.
OMAiFLNTMIT.
OrthoDBiEOG7QK0MD.
PhylomeDBiO59809.

Family and domain databases

Gene3Di1.25.10.10. 2 hits.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR013713. Cse1.
IPR001494. Importin-beta_N.
[Graphical view]
PfamiPF08506. Cse1. 1 hit.
PF03810. IBN_N. 1 hit.
[Graphical view]
SMARTiSM00913. IBN_N. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50166. IMPORTIN_B_NT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O59809-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLVEHFDAT LSADPNTRTK AELSLKQLEK EPSFVLAVLQ LLSSQEISLP
60 70 80 90 100
TQQAAVIYLK NRVSRSWSSI DDAPSPLDIP EEQKALFRQN ILPVLLQSPM
110 120 130 140 150
STRSHLMAIL NIILSTDFPE YWPGFSEYTS NLVHSTERCE VYAGLICFHE
160 170 180 190 200
LAKVYRWRLD DRQRDIGPLV AALFPTILQL GQGLINLEDN DSAEMLRLIL
210 220 230 240 250
KTFKSVIALE LPPELLANDM ILSWIQLLLA VVQKPLPESL MSLEPEVRQS
260 270 280 290 300
HVWHKCKKWA YYSLNRIFTR YGEPSSLVGD SANKYRAFAK NFITNVVPNI
310 320 330 340 350
LETYIQQTIL WTQGQLWLSP RVLYFLGCFY EECVKPKSTW ALLKPHLQLL
360 370 380 390 400
IGSFVFPQLC MSEEDEELWE LDPVEFIHKY IDIYDDFNSA DVAASRFLVK
410 420 430 440 450
LASKRKKYTF MGILSFASDI LNQYAASPPN EKNPRQKEGA LRMVAAVSNS
460 470 480 490 500
ILSKNSPVAG MMQDFLVAHV MPEFTSPVGY LRSRACEMIN RFSEIDWSDK
510 520 530 540 550
SQLLNAYQAV LNCLQDNDLP VRIQAALALQ PLMRHLEVHD VMTAHVPIIM
560 570 580 590 600
QNLLFLANEV DIDALSSCME EFVSSFSHEL TPFASQLAKQ LRNTFVKLMQ
610 620 630 640 650
ETMDESTTVD DFDSLVDDKS IAAIGILNTL STMILSLENT VDVLREIEAI
660 670 680 690 700
LLPMINFVLD NNIFDVYAEL FEIIDGCTFA SKEISPIMWG VYEKLQKVLK
710 720 730 740 750
ESGIEFVEEA TPALSNFITY GGKEFASRPD YIAVMVDIIM QVFNSEHLAV
760 770 780 790 800
NDRVSACKLT ELLMLNYRGL LDQYVPAFIE VAGNLLLVTE KPTSQTYRVF
810 820 830 840 850
LLEVIINALY YNPSMSLGVL EMHQWTLPFF ALWFENIPSF TRVHDKKLSL
860 870 880 890 900
VAILSVISLG AQQVAVAIQD SWGNIMKVMI TLLNTLPEAL AARAELEKEY
910 920 930 940 950
DGETFNLSGS GWNDGIDWEA DDDEGVDDFA VEYGGPDLGG EISADVVDDF
960 970 980 990 1000
DEFEHFQGNY LLDEDPLFHT LLDQVDPFSL FQEFMVHLKD NSPVTLQDLV
1010 1020
KNLEASEQQS LQRLVTEKPS TLAVASDKT
Length:1,029
Mass (Da):116,467
Last modified:August 1, 1998 - v1
Checksum:i6D1C73ADF40C374A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA19115.1.
PIRiT41386.
RefSeqiNP_588103.1. NM_001023094.2.

Genome annotation databases

EnsemblFungiiSPCC550.11.1; SPCC550.11.1:pep; SPCC550.11.
GeneIDi2539463.
KEGGispo:SPCC550.11.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA19115.1.
PIRiT41386.
RefSeqiNP_588103.1. NM_001023094.2.

3D structure databases

ProteinModelPortaliO59809.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276026. 52 interactions.
MINTiMINT-4676350.

Proteomic databases

MaxQBiO59809.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC550.11.1; SPCC550.11.1:pep; SPCC550.11.
GeneIDi2539463.
KEGGispo:SPCC550.11.

Organism-specific databases

EuPathDBiFungiDB:SPCC550.11.
PomBaseiSPCC550.11.

Phylogenomic databases

HOGENOMiHOG000163050.
InParanoidiO59809.
OMAiFLNTMIT.
OrthoDBiEOG7QK0MD.
PhylomeDBiO59809.

Enzyme and pathway databases

ReactomeiR-SPO-5578749. Transcriptional regulation by small RNAs.

Miscellaneous databases

PROiO59809.

Family and domain databases

Gene3Di1.25.10.10. 2 hits.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR013713. Cse1.
IPR001494. Importin-beta_N.
[Graphical view]
PfamiPF08506. Cse1. 1 hit.
PF03810. IBN_N. 1 hit.
[Graphical view]
SMARTiSM00913. IBN_N. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50166. IMPORTIN_B_NT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiIMA3_SCHPO
AccessioniPrimary (citable) accession number: O59809
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: August 1, 1998
Last modified: July 6, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.