Reviewed,
UniProtKB/Swiss-Prot O59711 (LYS9_SCHPO)
Last modified
November 25, 2008.
Version 35.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Saccharopine dehydrogenase [NADP+, L-glutamate-forming] EC=1.5.1.10 Alternative name(s): Saccharopine reductase | ||||
| Gene names |
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| Organism | Schizosaccharomyces pombe (Fission yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4896 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces |
Protein attributes
| Sequence length | 450 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NADP(+) + H(2)O = L-glutamate + L-2-aminoadipate 6-semialdehyde + NADPH. |
| Pathway | |
| Subunit structure | Homodimer By similarity. |
| Subcellular location | |
| Sequence similarities | Belongs to the saccharopine dehydrogenase family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Lysine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | lysine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytosol Ref.2 Inferred from direct assay. Source: GeneDB_SPombe |
| Molecular function | binding Inferred from electronic annotation. Source: InterPro saccharopine dehydrogenase (NADP+, L-glutamate-forming) activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 450 | 450 | Saccharopine dehydrogenase [NADP+, L-glutamate-forming] | PRO_0000316856 | |||
Sequences
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References
| [1] | "The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. Nurse P.Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972. |
| [2] | "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed: 16823372] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]. |
Cross-references
Sequence databases | |
|---|---|
| CU329671 Genomic DNA. Translation: CAA18292.1. | |
| PIR | T40337. |
| RefSeq | NP_596411.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1FF9 based on UniProtKB Q9P4R4. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2540908. |
| KEGG | spo:SPBC3B8.03. |
| NMPDR | fig|4896.1.peg.2277. |
Organism-specific databases | |
| GeneDB_Spombe | SPBC3B8.03. |
Gene expression databases | |
| ArrayExpress | O59711. |
Family and domain databases | |
| InterPro | IPR005097. Saccharopine_DHase. [Graphical view] |
| Pfam | PF03435. Saccharop_dh. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | LYS9_SCHPO | ||||||||
| Accession | Primary (citable) accession number: O59711 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

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