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Protein
Submitted name:

EchA protein

Gene

echA

Organism
Methanosarcina barkeri
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-12657.

Protein family/group databases

TCDBi3.D.1.4.2. the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family.

Names & Taxonomyi

Protein namesi
Submitted name:
EchA proteinImported
Gene namesi
Name:echAImported
OrganismiMethanosarcina barkeriImported
Taxonomic identifieri2208 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2318HelicalSequence analysisAdd
BLAST
Transmembranei30 – 4920HelicalSequence analysisAdd
BLAST
Transmembranei61 – 8222HelicalSequence analysisAdd
BLAST
Transmembranei89 – 10719HelicalSequence analysisAdd
BLAST
Transmembranei127 – 14721HelicalSequence analysisAdd
BLAST
Transmembranei159 – 17618HelicalSequence analysisAdd
BLAST
Transmembranei182 – 20221HelicalSequence analysisAdd
BLAST
Transmembranei214 – 23724HelicalSequence analysisAdd
BLAST
Transmembranei243 – 26927HelicalSequence analysisAdd
BLAST
Transmembranei281 – 30828HelicalSequence analysisAdd
BLAST
Transmembranei320 – 34122HelicalSequence analysisAdd
BLAST
Transmembranei348 – 36619HelicalSequence analysisAdd
BLAST
Transmembranei372 – 39423HelicalSequence analysisAdd
BLAST
Transmembranei415 – 43218HelicalSequence analysisAdd
BLAST
Transmembranei452 – 47221HelicalSequence analysisAdd
BLAST
Transmembranei493 – 51422HelicalSequence analysisAdd
BLAST
Transmembranei545 – 56420HelicalSequence analysisAdd
BLAST
Transmembranei617 – 63721HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi269797.Mbar_A0152.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini116 – 16348Proton_antipo_NInterPro annotationAdd
BLAST
Domaini179 – 464286Proton_antipo_MInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiarCOG01539. Archaea.
COG1009. LUCA.

Family and domain databases

InterProiIPR001750. ND/Mrp_mem.
IPR001516. Proton_antipo_N.
[Graphical view]
PfamiPF00361. Proton_antipo_M. 1 hit.
PF00662. Proton_antipo_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O59652-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIENTVMLLI IVPLLFSLLF VALPKSLYRY LAWAFFIIGV ALSVSLVLGG
60 70 80 90 100
TGVVPVEGPN FAMYENIVLL LEVLVILYIL AVSAKYKNWP TLGLGIISAA
110 120 130 140 150
LFAYTYANVP GAEGASFNID PLAQLMILIV NIVGTAIILF ATGYMDQYEE
160 170 180 190 200
HRHLNRQKIF YFTMSFFLAA MNGLVMSDTL GWLYLFWELT TLCSFVLISY
210 220 230 240 250
NMDEEGINNG FRALSLNLVG GVAMSIGIIL LATNYNISSL TGIATYAGTD
260 270 280 290 300
AVALAALALP VALLCIGGFA KSAQMPFHSW LLGAMVAPTP VSALLHSSTM
310 320 330 340 350
VNAGVFLVVK LVPAYANTSL GTAIAVYGSF TFVICSALAL SQRNAKRVLA
360 370 380 390 400
YSTIANLGLI IASAGIGTPL AVAASMMLIL FHAISKGLLF LCTGEIEHTI
410 420 430 440 450
GSRDIEDMSG LIKKAPLLTS IAALGMVSML LPPFGVLLTK WVSMEAASNN
460 470 480 490 500
PVVIIFIVLG SALTTVYYSK WLGTILSTSM DKNAVPHKKL ETYFPLSVLG
510 520 530 540 550
LSIIGTSIFI FSIYDYFIRP QVEILLKVAP AVTGQAGQFT SEIGAFAYAA
560 570 580 590 600
IFAVLALAIL IYLATKNMFT PRTAGYYMCG ENNLEKDRLM FRNGLCSYEK
610 620 630
CSVSNIYLQN IFGESKLTTF GYAISIILIV IALAGGVGL
Length:639
Mass (Da):68,696
Last modified:August 1, 1998 - v1
Checksum:iA69D3A22592EC8D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y16191 Genomic DNA. Translation: CAA76117.1.

Genome annotation databases

GeneIDi3626680.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y16191 Genomic DNA. Translation: CAA76117.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269797.Mbar_A0152.

Protein family/group databases

TCDBi3.D.1.4.2. the h(+) or na(+)-translocating nadh dehydrogenase (ndh) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3626680.

Phylogenomic databases

eggNOGiarCOG01539. Archaea.
COG1009. LUCA.

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-12657.

Family and domain databases

InterProiIPR001750. ND/Mrp_mem.
IPR001516. Proton_antipo_N.
[Graphical view]
PfamiPF00361. Proton_antipo_M. 1 hit.
PF00662. Proton_antipo_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "An Escherichia coli hydrogenase-3-type hydrogenase in methanogenic archaea."
    Kunkel A., Vorholt J.A., Thauer R.K., Hedderich R.
    Eur. J. Biochem. 252:467-476(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: FusaroImported.

Entry informationi

Entry nameiO59652_METBA
AccessioniPrimary (citable) accession number: O59652
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: December 9, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.