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O59648

- GLNA_METMP

UniProt

O59648 - GLNA_METMP

Protein

Glutamine synthetase

Gene

glnA

Organism
Methanococcus maripaludis (strain S2 / LL)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Aug 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. glutamate-ammonia ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glutamine biosynthetic process Source: InterPro
    2. nitrogen fixation Source: InterPro

    Keywords - Molecular functioni

    Ligase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMMAR267377:GJ77-1237-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamine synthetase (EC:6.3.1.2)
    Short name:
    GS
    Alternative name(s):
    Glutamate--ammonia ligase
    Gene namesi
    Name:glnA
    Ordered Locus Names:MMP1206
    OrganismiMethanococcus maripaludis (strain S2 / LL)
    Taxonomic identifieri267377 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
    ProteomesiUP000000590: Chromosome

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 446446Glutamine synthetasePRO_0000153205Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi267377.MMP1206.

    Structurei

    3D structure databases

    ProteinModelPortaliO59648.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutamine synthetase family.Curated

    Phylogenomic databases

    eggNOGiCOG0174.
    HOGENOMiHOG000005156.
    KOiK01915.
    OMAiIEWDMFR.

    Family and domain databases

    Gene3Di3.10.20.70. 1 hit.
    3.30.590.10. 1 hit.
    InterProiIPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR004809. Gln_synth_I.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view]
    PfamiPF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF54368. SSF54368. 1 hit.
    TIGRFAMsiTIGR00653. GlnA. 1 hit.
    PROSITEiPS00180. GLNA_1. 1 hit.
    PS00181. GLNA_ATP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O59648-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNAVEQAMEY IKTNNVKFIR FQFVDIHGEP KNIAYPVKAG AAGEEELYDV    50
    LEKGVYFDGS SIEGFVSIES SDMMLKPDLK TLSVLPWRPT EKSVARVICD 100
    VYTTNGKPFE GDPRGCLKRV LAKFDEELGG EFFVGPEPEF FILKEDACGS 150
    WVPADDAGYF DLEPLDGGCD IRRKIVFALE NLGFHVEASH HEVAEGQHEV 200
    DFKFADAVKT ADSVVTFKTT IKTLAAQDGL KATFMPKPFF GINGSGMHCH 250
    QSIWLNGEPS FYDESAQYQL SETCMSYVAG ILDHAKSIVA VTNPTVNSYK 300
    RLVPGYEAPV NIAWANSNRS AIVRVPAPRG KGTRIEFRAP DPACNPYLAF 350
    TVMLAAGLDG VKRKLSAIEP VEKNIFAMSE AQKKAEGIES VPANLKAALD 400
    ELENNSVLKD ALGKHIFENF IEIKNAEWDS FRTAVTDWET KQYLKI 446
    Length:446
    Mass (Da):49,421
    Last modified:August 1, 1998 - v1
    Checksum:iDDE984106651122A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF062391 Genomic DNA. Translation: AAD04845.1.
    BX950229 Genomic DNA. Translation: CAF30762.1.
    RefSeqiNP_988326.1. NC_005791.1.
    WP_011171150.1. NC_005791.1.

    Genome annotation databases

    EnsemblBacteriaiCAF30762; CAF30762; MMP1206.
    GeneIDi2761968.
    KEGGimmp:MMP1206.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF062391 Genomic DNA. Translation: AAD04845.1 .
    BX950229 Genomic DNA. Translation: CAF30762.1 .
    RefSeqi NP_988326.1. NC_005791.1.
    WP_011171150.1. NC_005791.1.

    3D structure databases

    ProteinModelPortali O59648.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 267377.MMP1206.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAF30762 ; CAF30762 ; MMP1206 .
    GeneIDi 2761968.
    KEGGi mmp:MMP1206.

    Phylogenomic databases

    eggNOGi COG0174.
    HOGENOMi HOG000005156.
    KOi K01915.
    OMAi IEWDMFR.

    Enzyme and pathway databases

    BioCyci MMAR267377:GJ77-1237-MONOMER.

    Family and domain databases

    Gene3Di 3.10.20.70. 1 hit.
    3.30.590.10. 1 hit.
    InterProi IPR008147. Gln_synt_beta.
    IPR014746. Gln_synth/guanido_kin_cat_dom.
    IPR008146. Gln_synth_cat_dom.
    IPR027303. Gln_synth_gly_rich_site.
    IPR004809. Gln_synth_I.
    IPR027302. Gln_synth_N_conserv_site.
    [Graphical view ]
    Pfami PF00120. Gln-synt_C. 1 hit.
    PF03951. Gln-synt_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54368. SSF54368. 1 hit.
    TIGRFAMsi TIGR00653. GlnA. 1 hit.
    PROSITEi PS00180. GLNA_1. 1 hit.
    PS00181. GLNA_ATP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Function and regulation of glnA in the methanogenic archaeon Methanococcus maripaludis."
      Cohen-Kupiec R., Marx C.J., Leigh J.A.
      J. Bacteriol. 181:256-261(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: S2 / LL.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S2 / LL.

    Entry informationi

    Entry nameiGLNA_METMP
    AccessioniPrimary (citable) accession number: O59648
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: August 1, 1998
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Caution

    Lacks the tyrosine conserved in bacteria and other archaea, involved in feedback inhibition.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3