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Protein

50S ribosomal protein L18

Gene

rpl18

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciPHOR70601:G1G39-1704-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L18UniRule annotation
Gene namesi
Name:rpl18UniRule annotation
Ordered Locus Names:PH1758
ORF Names:PHLG023
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001314151 – 20350S ribosomal protein L18Add BLAST203

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.UniRule annotation

Protein-protein interaction databases

STRINGi70601.PH1758

Structurei

3D structure databases

ProteinModelPortaliO59438
SMRiO59438
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL18 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04088 Archaea
COG0256 LUCA
HOGENOMiHOG000105947
KOiK02881
OMAiMAHGPRY
OrthoDBiPOG093Z0CXG

Family and domain databases

HAMAPiMF_01337_A Ribosomal_L18_A, 1 hit
InterProiView protein in InterPro
IPR005485 Rbsml_L5_euk/L18_arc
IPR025607 Rbsml_L5e/L18P_C
PANTHERiPTHR23410 PTHR23410, 2 hits
PfamiView protein in Pfam
PF14204 Ribosomal_L18_c, 1 hit
PF17144 Ribosomal_L5e, 2 hits
PRINTSiPR00058 RIBOSOMALL5

Sequencei

Sequence statusi: Complete.

O59438-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHGPRYRVP FRRRREGKTN YRKRLKLLKS GKPRLVVRKS LNHHIAQIIV
60 70 80 90 100
YDPKGDRTLV SAHTRELIRD FGWKGHCGNT PSAYLLGLLI GYKAKKAGIE
110 120 130 140 150
EAILDIGLHP PVRGSSIFAV LKGAIDAGLN VPHSPEIFPE DYRIRGEHIA
160 170 180 190 200
EYARMLKEQD EDRFRRQFGG YLEKGLDPEK LPEHFEEVKA RIIEKFESEG

ARE
Length:203
Mass (Da):23,317
Last modified:February 21, 2001 - v2
Checksum:i9AEEAE1CA253D42B
GO

Sequence cautioni

The sequence BAA30872 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA Translation: BAA30872.1 Different initiation.
PIRiA71185
RefSeqiWP_010885822.1, NC_000961.1

Genome annotation databases

EnsemblBacteriaiBAA30872; BAA30872; BAA30872
GeneIDi1442603
KEGGipho:PH1758

Similar proteinsi

Entry informationi

Entry nameiRL18_PYRHO
AccessioniPrimary (citable) accession number: O59438
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: February 21, 2001
Last modified: April 25, 2018
This is version 98 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health