O59394 (O59394_PYRHO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
323aa long hypothetical 3-isopropylmalate dehydrogenase EMBL BAA30836.1

Gene names

Ordered Locus Names:

PH1722

Organism

Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) [Complete proteome] [HAMAP]

Taxonomic identifier

70601 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	323 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004444
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O59394 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 7ADE88813F3BE7B3	FASTA	323	36,469
	10 20 30 40 50 60 MVKSVTDKIK FYEFEGGLSV FKKYGVPIRE EDLEEIRKMD AILFGATTTP FDVPRYKSLI 70 80 90 100 110 120 ITLRKELDLY ANLRIIPNFK LRKEIIIVRE NSEGLYSGEG AYDSNKVVDF RIITRKGAER 130 140 150 160 170 180 IAKFAVKLAK DRSTFLTFVH KANILESDRF FRKIVLDIAR KEDVKVREEI VDSFTIKLVK 190 200 210 220 230 240 DPWNLGIILS ENMFGDILSD LATIHAGSIG IVPSGNYGED IALFEPIHGS APDIAGKGIA 250 260 270 280 290 300 NPIGAILSAA MMLDYLGLDG SIIWKAVGRY VRRGNLTPDM EGRATTLEVT NGIISEIYRL 310 320 DEYEIDEVWR DEVRLGRILL EIS

References

[1]

"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3." Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T. , Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kikuchi H. DNA Res. 5:55-76(1998) [PubMed: 9679194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3 and OT3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000001 Genomic DNA. Translation: BAA30836.1.
PIR	E71180.
RefSeq	NP_143563.2. NC_000961.1.
3D structure databases
HSSP	HSSP built from PDB template 2AYQ based on UniProtKB P12010.
ProteinModelPortal	O59394.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000000182; EBPYRP00000000182; EBPYRG00000000182.
GeneID	1442568.
GenomeReviews	Gene locus PH1722 in contig BA000001_GR.
KEGG	pho:PH1722.
NMPDR	fig|70601.1.peg.1682.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000022922.
HOGENOM	HBG518924.
OMA	HAGSIGI.
PhylomeDB	O59394.
ProtClustDB	PRK00772.
Enzyme and pathway databases
BioCyc	PHOR70601:PH1722-MONOMER.
Family and domain databases
InterPro	IPR019818. IsoCit/isopropylmalate_DH_CS. IPR001804. Isocitrate/isopropylmalate_DH. IPR024084. IsoPropMal-DH-like_dom. [Graphical view]
Gene3D	G3DSA:3.40.718.10. IDH_IMDH. 1 hit.
KO	K00052.
PANTHER	PTHR11835. IDH_IMDH_dimeric. 1 hit.
Pfam	PF00180. Iso_dh. 1 hit. [Graphical view]
PROSITE	PS00470. IDH_IMDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O59394_PYRHO

Accession

Primary (citable) accession number: O59394

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	August 1, 1998
Last modified:	December 14, 2011
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)