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Protein

HTH-type transcriptional regulator LrpA

Gene

lrpA

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Negatively regulates its own transcription.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi21 – 40H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciPHOR70601:G1G39-1545-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator LrpA
Gene namesi
Name:lrpA
Ordered Locus Names:PH1592
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001117721 – 141HTH-type transcriptional regulator LrpAAdd BLAST141

Interactioni

Protein-protein interaction databases

STRINGi70601.PH1592

Structurei

3D structure databases

ProteinModelPortaliO59256
SMRiO59256
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 63HTH asnC-typePROSITE-ProRule annotationAdd BLAST62

Phylogenomic databases

eggNOGiarCOG01580 Archaea
COG1522 LUCA
HOGENOMiHOG000115326
KOiK03718
OMAiGDHMIMA
OrthoDBiPOG093Z0D8J

Family and domain databases

CDDicd00090 HTH_ARSR, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011991 ArsR-like_HTH
IPR000485 AsnC-type_HTH_dom
IPR011008 Dimeric_a/b-barrel
IPR019888 Tscrpt_reg_AsnC-typ
IPR019887 Tscrpt_reg_AsnC/Lrp_C
IPR019885 Tscrpt_reg_HTH_AsnC-type_CS
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF01037 AsnC_trans_reg, 1 hit
PRINTSiPR00033 HTHASNC
SMARTiView protein in SMART
SM00344 HTH_ASNC, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF54909 SSF54909, 1 hit
PROSITEiView protein in PROSITE
PS00519 HTH_ASNC_1, 1 hit
PS50956 HTH_ASNC_2, 1 hit

Sequencei

Sequence statusi: Complete.

O59256-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIDERDKIIL EILSKDARTP FTEIAKKLGI SETAVRKRVK ALEEKGIIEG
60 70 80 90 100
YTIRINPKKL GYSLVTITGV DTRPEKLFEV AEKLKEFEFV RELYLSSGDH
110 120 130 140
MIMAVIWARD GEDLADIISN KIGKIDGVTK VCPAIILEKL K
Length:141
Mass (Da):15,932
Last modified:August 1, 1998 - v1
Checksum:i08B103E4B86078F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA Translation: BAA30704.1
PIRiH71037
RefSeqiWP_010885666.1, NC_000961.1

Genome annotation databases

EnsemblBacteriaiBAA30704; BAA30704; BAA30704
GeneIDi1442445
KEGGipho:PH1592

Similar proteinsi

Entry informationi

Entry nameiREG7_PYRHO
AccessioniPrimary (citable) accession number: O59256
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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