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O59240

- PDAD_PYRHO

UniProt

O59240 - PDAD_PYRHO

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Protein
Pyruvoyl-dependent arginine decarboxylase
Gene
pdaD, PH1609
Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-arginine = agmatine + CO2.UniRule annotation

Cofactori

Pyruvoyl group By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei43 – 442Cleavage (non-hydrolytic) By similarity

GO - Molecular functioni

  1. arginine decarboxylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. arginine catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Ligandi

Pyruvate

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-1610-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvoyl-dependent arginine decarboxylase (EC:4.1.1.19)
Short name:
PvlArgDC
Cleaved into the following 2 chains:
Gene namesi
Name:pdaD
Ordered Locus Names:PH1609
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000000752: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 4343Pyruvoyl-dependent arginine decarboxylase subunit beta By similarity
PRO_0000023332Add
BLAST
Chaini44 – 158115Pyruvoyl-dependent arginine decarboxylase subunit alpha By similarity
PRO_0000023333Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei44 – 441Pyruvic acid (Ser) By similarity

Interactioni

Protein-protein interaction databases

STRINGi70601.PH1609.

Structurei

3D structure databases

ProteinModelPortaliO59240.
SMRiO59240. Positions 3-43.

Family & Domainsi

Sequence similaritiesi

Belongs to the PdaD family.

Phylogenomic databases

eggNOGiCOG1945.
HOGENOMiHOG000012204.
KOiK02626.
OMAiISSIMPP.

Family and domain databases

Gene3Di3.50.20.10. 1 hit.
HAMAPiMF_01404. PvlArgDC.
InterProiIPR016104. Pyr-dep_his/arg-deCO2ase.
IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
IPR002724. Pyruvoyl-dep_arg_deCO2ase.
[Graphical view]
PfamiPF01862. PvlArgDC. 1 hit.
[Graphical view]
PIRSFiPIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDomiPD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF56271. SSF56271. 1 hit.
TIGRFAMsiTIGR00286. TIGR00286. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O59240-1 [UniParc]FASTAAdd to Basket

« Hide

MTWITPKKAI MLAAAAEGGT KLNAFDNALL KMGIGNVNLV KLSSVIPAHI    50
EWLDELPKNI PIGMLLPTVY AHIESDEPGS TISAALGVGI SEGNEGGLIY 100
EYAGYCKREE AEDMVRKMVE EGFKVRGWKL KEFKVVSAEI TVKEKPAAAV 150
AAVIMFPY 158
Length:158
Mass (Da):17,124
Last modified:August 1, 1998 - v1
Checksum:i7D9CE49C99E8D7FB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000001 Genomic DNA. Translation: BAA30721.1.
PIRiA71040.
RefSeqiNP_143462.1. NC_000961.1.

Genome annotation databases

EnsemblBacteriaiBAA30721; BAA30721; BAA30721.
GeneIDi1442461.
KEGGipho:PH1609.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000001 Genomic DNA. Translation: BAA30721.1 .
PIRi A71040.
RefSeqi NP_143462.1. NC_000961.1.

3D structure databases

ProteinModelPortali O59240.
SMRi O59240. Positions 3-43.
ModBasei Search...

Protein-protein interaction databases

STRINGi 70601.PH1609.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA30721 ; BAA30721 ; BAA30721 .
GeneIDi 1442461.
KEGGi pho:PH1609.

Phylogenomic databases

eggNOGi COG1945.
HOGENOMi HOG000012204.
KOi K02626.
OMAi ISSIMPP.

Enzyme and pathway databases

BioCyci PHOR70601:GJWR-1610-MONOMER.

Family and domain databases

Gene3Di 3.50.20.10. 1 hit.
HAMAPi MF_01404. PvlArgDC.
InterProi IPR016104. Pyr-dep_his/arg-deCO2ase.
IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
IPR002724. Pyruvoyl-dep_arg_deCO2ase.
[Graphical view ]
Pfami PF01862. PvlArgDC. 1 hit.
[Graphical view ]
PIRSFi PIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDomi PD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF56271. SSF56271. 1 hit.
TIGRFAMsi TIGR00286. TIGR00286. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3.

Entry informationi

Entry nameiPDAD_PYRHO
AccessioniPrimary (citable) accession number: O59240
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: August 1, 1998
Last modified: May 14, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi