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O59240 (PDAD_PYRHO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pyruvoyl-dependent arginine decarboxylase

Short name=PvlArgDC
EC=4.1.1.19
Gene names
Name:pdaD
Ordered Locus Names:PH1609
OrganismPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) [Complete proteome] [HAMAP]
Taxonomic identifier70601 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length158 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01404

Cofactor

Pyruvoyl group By similarity. HAMAP-Rule MF_01404

Sequence similarities

Belongs to the PdaD family.

Ontologies

Keywords
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginine catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionarginine decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4343Pyruvoyl-dependent arginine decarboxylase subunit beta By similarity
PRO_0000023332
Chain44 – 158115Pyruvoyl-dependent arginine decarboxylase subunit alpha By similarity
PRO_0000023333

Sites

Site43 – 442Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue441Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
O59240 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 7D9CE49C99E8D7FB

FASTA15817,124
        10         20         30         40         50         60 
MTWITPKKAI MLAAAAEGGT KLNAFDNALL KMGIGNVNLV KLSSVIPAHI EWLDELPKNI 

        70         80         90        100        110        120 
PIGMLLPTVY AHIESDEPGS TISAALGVGI SEGNEGGLIY EYAGYCKREE AEDMVRKMVE 

       130        140        150 
EGFKVRGWKL KEFKVVSAEI TVKEKPAAAV AAVIMFPY 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000001 Genomic DNA. Translation: BAA30721.1.
PIRA71040.
RefSeqNP_143462.1. NC_000961.1.

3D structure databases

ProteinModelPortalO59240.
SMRO59240. Positions 3-43.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING70601.PH1609.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA30721; BAA30721; BAA30721.
GeneID1442461.
KEGGpho:PH1609.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1945.
HOGENOMHOG000012204.
KOK02626.
OMAISSIMPP.

Enzyme and pathway databases

BioCycPHOR70601:GJWR-1610-MONOMER.

Family and domain databases

Gene3D3.50.20.10. 1 hit.
HAMAPMF_01404. PvlArgDC.
InterProIPR016104. Pyr-dep_his/arg-deCO2ase.
IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
IPR002724. Pyruvoyl-dep_arg_deCO2ase.
[Graphical view]
PfamPF01862. PvlArgDC. 1 hit.
[Graphical view]
PIRSFPIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDomPD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56271. SSF56271. 1 hit.
TIGRFAMsTIGR00286. TIGR00286. 1 hit.
ProtoNetSearch...

Entry information

Entry namePDAD_PYRHO
AccessionPrimary (citable) accession number: O59240
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: August 1, 1998
Last modified: May 14, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families