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O59227 (O59227_PYRHO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase RuleBase RU004279
EC=2.7.7.6 RuleBase RU004279
Gene names
Ordered Locus Names:PH1545
OrganismPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) [Complete proteome] [HAMAP]
Taxonomic identifier70601 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length907 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). RuleBase RU004279

Sequence similarities

Belongs to the RNA polymerase beta' chain family. RuleBase RU004279

Sequences

Sequence LengthMass (Da)Tools
O59227 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: FF837E9881876E6B

FASTA907102,977
        10         20         30         40         50         60 
MHSVKKVIGS IEFGILSPQE IRKMSAVEVT VPDTYDDDGY PIEGGVMDKR MGVIDPGLRC 

        70         80         90        100        110        120 
ETCGAKAGEC PGHFGHIELA RPVIHVGFAK TIHRILESTC RECGRIKLTD EEIEEYMKKL 

       130        140        150        160        170        180 
ELAKNRRSEV NKILKEIHKK ARERMVCPHC GAPQYPIKFE KPTIYWELRK DEQGNEYKHR 

       190        200        210        220        230        240 
MMPTEIRDRL EKIPDKDLPL LGLHPEKSRP EWMVLTVLPV PPVTVRPSIT LETGIRAEDD 

       250        260        270        280        290        300 
LTHKLVDIIR INNRLRQNIE AGAPQLIIED LWDLLQYHVT TYINNETSGV PPAKHKSGRP 

       310        320        330        340        350        360 
LKTLAQRLKG KEGRFRGNLS GKRVNFSART VISPDPMISI NEVGVPIQIA MELTVPEKVT 

       370        380        390        400        410        420 
EFNIEKLRKM VLNGPDKYPG ANYVIDPEGR RIRIMESNKE NLAKMIDIGW TVERHLVDGD 

       430        440        450        460        470        480 
IVLFNRQPSL HRMSIMAHRV RVMPYKTFRL NLAVCPPYNA DFDGDEMNLH VPQTEEAQAE 

       490        500        510        520        530        540 
AKILMEVQNH IISPRYGGPI IGGIQDHISG GYLLTREGAY FTREEVEQML MFAGVDIKEL 

       550        560        570        580        590        600 
PEPDKYENGK PLWSGKTIFS LLLPDDLTVW YRNKLCDEEE KCEALEKLIE EKLIPDPEEV 

       610        620        630        640        650        660 
RKLAYDGFVY IQNGKLLSGA IDKKAYGRED GIILDLIVRE YGVERARQFL DQVTKLTIWV 

       670        680        690        700        710        720 
ITHKGFTTGI DDEDLPEEAR DRIREIIREA EERVQRLIEA YKRGELEPLP GKSLEETLES 

       730        740        750        760        770        780 
KIMAVLAEAR DNAGSVAEKY LGMNNHAVIM AKTGARGKIL NITQMAALLG QQSIRGRRLY 

       790        800        810        820        830        840 
RGFKGRVLSH FKPGDLGARA KGFVVNSYKS GLSPQEYFFH AMGGREGLVD TAVRTAQSGY 

       850        860        870        880        890        900 
MQRRLINALQ DLKVDYDGTV RDPTGVIVQF RYGEDGVDPM KSWGGKTVDV DRVIVRTLIK 


MRSNGKK

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References

[1]"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3."
Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T. expand/collapse author list , Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kikuchi H.
DNA Res. 5:55-76(1998) [PubMed: 9679194] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3 and OT3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000001 Genomic DNA. Translation: BAA30656.1.
PIRH71031.
RefSeqNP_143406.1. NC_000961.1.

3D structure databases

HSSPHSSP built from PDB template 1I6H based on UniProtKB P04050.
ProteinModelPortalO59227.
SMRO59227. Positions 6-897.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBPYRT00000000767; EBPYRP00000000767; EBPYRG00000000767.
GeneID1443864.
GenomeReviewsGene locus PH1545 in contig BA000001_GR.
KEGGpho:PH1545.
NMPDRfig|70601.1.peg.1517.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000022344.
HOGENOMHBG499785.
OMAHKLVDII.
PhylomeDBO59227.
ProtClustDBPRK08566.

Enzyme and pathway databases

BioCycPHOR70601:PH1545-MONOMER.

Family and domain databases

InterProIPR012758. DNA-dir_RpoA1.
IPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
[Graphical view]
KOK03041.
PfamPF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 1 hit.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
SMARTSM00663. RPOLA_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR02390. RNA_pol_rpoA1. 1 hit.
ProtoNetSearch...

Entry information

Entry nameO59227_PYRHO
AccessionPrimary (citable) accession number: O59227
Entry history
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: December 14, 2011
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info