Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized HTH-type transcriptional regulator PH1519

Gene

PH1519

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi24 – 4320H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-1520-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator PH1519
Gene namesi
Ordered Locus Names:PH1519
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 151151Uncharacterized HTH-type transcriptional regulator PH1519PRO_0000111769Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi70601.PH1519.

Structurei

Secondary structure

1
151
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi7 – 1812Combined sources
Helixi24 – 318Combined sources
Helixi35 – 4814Combined sources
Beta strandi49 – 513Combined sources
Beta strandi53 – 586Combined sources
Helixi60 – 634Combined sources
Beta strandi67 – 759Combined sources
Helixi80 – 889Combined sources
Beta strandi93 – 986Combined sources
Beta strandi100 – 11314Combined sources
Helixi114 – 12512Combined sources
Beta strandi130 – 1378Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1RI7X-ray2.70A1-151[»]
2CYYX-ray1.80A1-151[»]
2E1CX-ray2.10A1-151[»]
2ZNYX-ray2.59A/B/C/D/E/F/G/H1-151[»]
2ZNZX-ray2.39A/B/C/D/E/F/G/H1-151[»]
ProteinModelPortaliO59188.
SMRiO59188. Positions 1-151.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO59188.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 6662HTH asnC-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH asnC-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiarCOG01580. Archaea.
COG1522. LUCA.
HOGENOMiHOG000115326.
KOiK03718.
OMAiPGVEGTH.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.30.70.920. 1 hit.
InterProiIPR000485. AsnC-type_HTH_dom.
IPR011008. Dimeric_a/b-barrel.
IPR019888. Tscrpt_reg_AsnC-typ.
IPR019887. Tscrpt_reg_AsnC/Lrp_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01037. AsnC_trans_reg. 1 hit.
PF13404. HTH_AsnC-type. 1 hit.
[Graphical view]
PRINTSiPR00033. HTHASNC.
SMARTiSM00344. HTH_ASNC. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF54909. SSF54909. 1 hit.
PROSITEiPS50956. HTH_ASNC_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O59188-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVPLDEIDK KIIKILQNDG KAPLREISKI TGLAESTIHE RIRKLRESGV
60 70 80 90 100
IKKFTAIIDP EALGYSMLAF ILVKVKAGKY SEVASNLAKY PEIVEVYETT
110 120 130 140 150
GDYDMVVKIR TKNSEELNNF LDLIGSIPGV EGTHTMIVLK THKETTELPI

K
Length:151
Mass (Da):16,954
Last modified:August 1, 1998 - v1
Checksum:iFD7BD105608588E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA30629.1.
PIRiE71028.
RefSeqiWP_010885596.1. NC_000961.1.

Genome annotation databases

EnsemblBacteriaiBAA30629; BAA30629; BAA30629.
GeneIDi1443836.
KEGGipho:PH1519.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA30629.1.
PIRiE71028.
RefSeqiWP_010885596.1. NC_000961.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1RI7X-ray2.70A1-151[»]
2CYYX-ray1.80A1-151[»]
2E1CX-ray2.10A1-151[»]
2ZNYX-ray2.59A/B/C/D/E/F/G/H1-151[»]
2ZNZX-ray2.39A/B/C/D/E/F/G/H1-151[»]
ProteinModelPortaliO59188.
SMRiO59188. Positions 1-151.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi70601.PH1519.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA30629; BAA30629; BAA30629.
GeneIDi1443836.
KEGGipho:PH1519.

Phylogenomic databases

eggNOGiarCOG01580. Archaea.
COG1522. LUCA.
HOGENOMiHOG000115326.
KOiK03718.
OMAiPGVEGTH.

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-1520-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO59188.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.30.70.920. 1 hit.
InterProiIPR000485. AsnC-type_HTH_dom.
IPR011008. Dimeric_a/b-barrel.
IPR019888. Tscrpt_reg_AsnC-typ.
IPR019887. Tscrpt_reg_AsnC/Lrp_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01037. AsnC_trans_reg. 1 hit.
PF13404. HTH_AsnC-type. 1 hit.
[Graphical view]
PRINTSiPR00033. HTHASNC.
SMARTiSM00344. HTH_ASNC. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF54909. SSF54909. 1 hit.
PROSITEiPS50956. HTH_ASNC_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiREG6_PYRHO
AccessioniPrimary (citable) accession number: O59188
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: August 1, 1998
Last modified: September 7, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.