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Protein

Uncharacterized HTH-type transcriptional regulator PH1519

Gene

PH1519

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi24 – 43H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-1519-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator PH1519
Gene namesi
Ordered Locus Names:PH1519
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001117691 – 151Uncharacterized HTH-type transcriptional regulator PH1519Add BLAST151

Interactioni

Protein-protein interaction databases

STRINGi70601.PH1519.

Structurei

Secondary structure

1151
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi7 – 18Combined sources12
Helixi24 – 31Combined sources8
Helixi35 – 48Combined sources14
Beta strandi49 – 51Combined sources3
Beta strandi53 – 58Combined sources6
Helixi60 – 63Combined sources4
Beta strandi67 – 75Combined sources9
Helixi80 – 88Combined sources9
Beta strandi93 – 98Combined sources6
Beta strandi100 – 113Combined sources14
Helixi114 – 125Combined sources12
Beta strandi130 – 137Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1RI7X-ray2.70A1-151[»]
2CYYX-ray1.80A1-151[»]
2E1CX-ray2.10A1-151[»]
2ZNYX-ray2.59A/B/C/D/E/F/G/H1-151[»]
2ZNZX-ray2.39A/B/C/D/E/F/G/H1-151[»]
ProteinModelPortaliO59188.
SMRiO59188.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO59188.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 66HTH asnC-typePROSITE-ProRule annotationAdd BLAST62

Sequence similaritiesi

Contains 1 HTH asnC-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiarCOG01580. Archaea.
COG1522. LUCA.
HOGENOMiHOG000115326.
KOiK03718.
OMAiPGVEGTH.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.30.70.920. 1 hit.
InterProiIPR000485. AsnC-type_HTH_dom.
IPR011008. Dimeric_a/b-barrel.
IPR019888. Tscrpt_reg_AsnC-typ.
IPR019887. Tscrpt_reg_AsnC/Lrp_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01037. AsnC_trans_reg. 1 hit.
PF13404. HTH_AsnC-type. 1 hit.
[Graphical view]
PRINTSiPR00033. HTHASNC.
SMARTiSM00344. HTH_ASNC. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF54909. SSF54909. 1 hit.
PROSITEiPS50956. HTH_ASNC_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O59188-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVPLDEIDK KIIKILQNDG KAPLREISKI TGLAESTIHE RIRKLRESGV
60 70 80 90 100
IKKFTAIIDP EALGYSMLAF ILVKVKAGKY SEVASNLAKY PEIVEVYETT
110 120 130 140 150
GDYDMVVKIR TKNSEELNNF LDLIGSIPGV EGTHTMIVLK THKETTELPI

K
Length:151
Mass (Da):16,954
Last modified:August 1, 1998 - v1
Checksum:iFD7BD105608588E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA30629.1.
PIRiE71028.
RefSeqiWP_010885596.1. NC_000961.1.

Genome annotation databases

EnsemblBacteriaiBAA30629; BAA30629; BAA30629.
GeneIDi1443836.
KEGGipho:PH1519.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA. Translation: BAA30629.1.
PIRiE71028.
RefSeqiWP_010885596.1. NC_000961.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1RI7X-ray2.70A1-151[»]
2CYYX-ray1.80A1-151[»]
2E1CX-ray2.10A1-151[»]
2ZNYX-ray2.59A/B/C/D/E/F/G/H1-151[»]
2ZNZX-ray2.39A/B/C/D/E/F/G/H1-151[»]
ProteinModelPortaliO59188.
SMRiO59188.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi70601.PH1519.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA30629; BAA30629; BAA30629.
GeneIDi1443836.
KEGGipho:PH1519.

Phylogenomic databases

eggNOGiarCOG01580. Archaea.
COG1522. LUCA.
HOGENOMiHOG000115326.
KOiK03718.
OMAiPGVEGTH.

Enzyme and pathway databases

BioCyciPHOR70601:GJWR-1519-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO59188.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.30.70.920. 1 hit.
InterProiIPR000485. AsnC-type_HTH_dom.
IPR011008. Dimeric_a/b-barrel.
IPR019888. Tscrpt_reg_AsnC-typ.
IPR019887. Tscrpt_reg_AsnC/Lrp_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01037. AsnC_trans_reg. 1 hit.
PF13404. HTH_AsnC-type. 1 hit.
[Graphical view]
PRINTSiPR00033. HTHASNC.
SMARTiSM00344. HTH_ASNC. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF54909. SSF54909. 1 hit.
PROSITEiPS50956. HTH_ASNC_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiREG6_PYRHO
AccessioniPrimary (citable) accession number: O59188
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: August 1, 1998
Last modified: November 2, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.