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Protein

Uncharacterized HTH-type transcriptional regulator PH1519

Gene

PH1519

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi24 – 43H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciPHOR70601:G1G39-1476-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator PH1519
Gene namesi
Ordered Locus Names:PH1519
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001117691 – 151Uncharacterized HTH-type transcriptional regulator PH1519Add BLAST151

Proteomic databases

PRIDEiO59188

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

IntActiO59188, 1 interactor
STRINGi70601.PH1519

Structurei

Secondary structure

1151
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi7 – 18Combined sources12
Helixi24 – 31Combined sources8
Helixi35 – 48Combined sources14
Beta strandi49 – 51Combined sources3
Beta strandi53 – 58Combined sources6
Helixi60 – 63Combined sources4
Beta strandi67 – 75Combined sources9
Helixi80 – 88Combined sources9
Beta strandi93 – 98Combined sources6
Beta strandi100 – 113Combined sources14
Helixi114 – 125Combined sources12
Beta strandi130 – 137Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1RI7X-ray2.70A1-151[»]
2CYYX-ray1.80A1-151[»]
2E1CX-ray2.10A1-151[»]
2ZNYX-ray2.59A/B/C/D/E/F/G/H1-151[»]
2ZNZX-ray2.39A/B/C/D/E/F/G/H1-151[»]
ProteinModelPortaliO59188
SMRiO59188
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO59188

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 66HTH asnC-typePROSITE-ProRule annotationAdd BLAST62

Phylogenomic databases

eggNOGiarCOG01580 Archaea
COG1522 LUCA
HOGENOMiHOG000115326
KOiK03718
OMAiLDERIVH
OrthoDBiPOG093Z0D8J

Family and domain databases

CDDicd00090 HTH_ARSR, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011991 ArsR-like_HTH
IPR000485 AsnC-type_HTH_dom
IPR011008 Dimeric_a/b-barrel
IPR019888 Tscrpt_reg_AsnC-typ
IPR019887 Tscrpt_reg_AsnC/Lrp_C
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF01037 AsnC_trans_reg, 1 hit
PF13404 HTH_AsnC-type, 1 hit
PRINTSiPR00033 HTHASNC
SMARTiView protein in SMART
SM00344 HTH_ASNC, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF54909 SSF54909, 1 hit
PROSITEiView protein in PROSITE
PS50956 HTH_ASNC_2, 1 hit

Sequencei

Sequence statusi: Complete.

O59188-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVPLDEIDK KIIKILQNDG KAPLREISKI TGLAESTIHE RIRKLRESGV
60 70 80 90 100
IKKFTAIIDP EALGYSMLAF ILVKVKAGKY SEVASNLAKY PEIVEVYETT
110 120 130 140 150
GDYDMVVKIR TKNSEELNNF LDLIGSIPGV EGTHTMIVLK THKETTELPI

K
Length:151
Mass (Da):16,954
Last modified:August 1, 1998 - v1
Checksum:iFD7BD105608588E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA Translation: BAA30629.1
PIRiE71028
RefSeqiWP_010885596.1, NC_000961.1

Genome annotation databases

EnsemblBacteriaiBAA30629; BAA30629; BAA30629
GeneIDi1443836
KEGGipho:PH1519

Entry informationi

Entry nameiREG6_PYRHO
AccessioniPrimary (citable) accession number: O59188
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: August 1, 1998
Last modified: May 23, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

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