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O59150 (RNP2_PYRHO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component 2

Short name=RNase P component 2
EC=3.1.26.5
Gene names
Name:rnp2
Ordered Locus Names:PH1481
OrganismPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) [Complete proteome] [HAMAP]
Taxonomic identifier70601 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length120 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00755

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00755

Subunit structure

Consists of a catalytic RNA component and at least 4 protein subunits Potential.

Sequence similarities

Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionHydrolase
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological_processtRNA 5'-leader removal

Inferred from electronic annotation. Source: InterPro

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Binary interactions

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 120120Ribonuclease P protein component 2 HAMAP-Rule MF_00755
PRO_0000140027

Secondary structure

.................. 120
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
O59150 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: C78C9EF6C5380E53

FASTA12014,044
        10         20         30         40         50         60 
MMRKLKTLPP TLRDKNRYIA FEIISDGDFT KDEVKELIWK SSLEVLGETG TAIVKPWLIK 

        70         80         90        100        110        120 
FDPNTKTGIV RCDREYVEYL RFALMLVSEF NGKRLIIRTL GVSGTIKRLK RKFLAKYGWK 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000001 Genomic DNA. Translation: BAA30588.1.
PIRD71023.
RefSeqNP_143344.1. NC_000961.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2CZVX-ray2.00C/D1-120[»]
ProteinModelPortalO59150.
SMRO59150. Positions 2-120.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActO59150. 2 interactions.
STRING70601.PH1481.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA30588; BAA30588; BAA30588.
GeneID1443798.
KEGGpho:PH1481.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1369.
HOGENOMHOG000286243.
KOK03537.
OMANPWLIDY.
ProtClustDBPRK03717.

Enzyme and pathway databases

BioCycPHOR70601:GJWR-1479-MONOMER.

Family and domain databases

HAMAPMF_00755. RNase_P_2.
InterProIPR002759. RNase_P/MRP_subunit.
IPR016434. RNase_P_comp-2.
[Graphical view]
PfamPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]
PIRSFPIRSF004952. RNase_P_2. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceO59150.

Entry information

Entry nameRNP2_PYRHO
AccessionPrimary (citable) accession number: O59150
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: August 1, 1998
Last modified: April 16, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references