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Protein

Putative sugar kinase PH1459

Gene

PH1459

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei194ATPCombined sources1
Binding sitei219ATPCombined sources1
Binding sitei224ATP; via carbonyl oxygenCombined sources1

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sugar kinase PH1459Curated (EC:2.7.1.-Curated)
Gene namesi
Ordered Locus Names:PH1459
ORF Names:PHCC008
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000801531 – 310Putative sugar kinase PH1459Add BLAST310

Interactioni

Protein-protein interaction databases

STRINGi70601.PH1459

Structurei

Secondary structure

1310
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi8 – 12Combined sources5
Beta strandi15 – 24Combined sources10
Turni26 – 28Combined sources3
Beta strandi31 – 37Combined sources7
Helixi39 – 49Combined sources11
Beta strandi53 – 63Combined sources11
Helixi64 – 75Combined sources12
Beta strandi83 – 89Combined sources7
Beta strandi92 – 97Combined sources6
Beta strandi99 – 102Combined sources4
Beta strandi104 – 107Combined sources4
Helixi112 – 114Combined sources3
Helixi118 – 120Combined sources3
Helixi123 – 128Combined sources6
Beta strandi130 – 136Combined sources7
Helixi137 – 140Combined sources4
Helixi144 – 155Combined sources12
Beta strandi159 – 164Combined sources6
Helixi169 – 172Combined sources4
Helixi176 – 189Combined sources14
Beta strandi191 – 196Combined sources6
Helixi197 – 204Combined sources8
Turni205 – 207Combined sources3
Beta strandi213 – 219Combined sources7
Helixi221 – 223Combined sources3
Beta strandi224 – 229Combined sources6
Beta strandi232 – 237Combined sources6
Helixi249 – 263Combined sources15
Beta strandi264 – 266Combined sources3
Helixi269 – 283Combined sources15
Helixi295 – 298Combined sources4
Helixi302 – 308Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3EWMX-ray1.90A/B8-309[»]
3GBUX-ray2.20A/B/C/D8-309[»]
3IH0X-ray1.90A/B8-309[»]
ProteinModelPortaliO59128
SMRiO59128
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO59128

Family & Domainsi

Sequence similaritiesi

Belongs to the carbohydrate kinase PfkB family.Curated

Phylogenomic databases

eggNOGiarCOG00014 Archaea
COG0524 LUCA
HOGENOMiHOG000235951
KOiK00847
OMAiFDCLADQ
OrthoDBiPOG093Z05SL

Family and domain databases

Gene3Di3.40.1190.20, 1 hit
InterProiView protein in InterPro
IPR002173 Carboh/pur_kinase_PfkB_CS
IPR011611 PfkB_dom
IPR002139 Ribo/fructo_kinase
IPR029056 Ribokinase-like
PfamiView protein in Pfam
PF00294 PfkB, 1 hit
PRINTSiPR00990 RIBOKINASE
SUPFAMiSSF53613 SSF53613, 1 hit
PROSITEiView protein in PROSITE
PS00583 PFKB_KINASES_1, 1 hit
PS00584 PFKB_KINASES_2, 1 hit

Sequencei

Sequence statusi: Complete.

O59128-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLVFGMIAS IGELLIDLIS VEEGDLKDVR LFEKHPGGAP ANVAVGVSRL
60 70 80 90 100
GVKSSLISKV GNDPFGEYLI EELSKENVDT RGIVKDEKKH TGIVFVQLKG
110 120 130 140 150
ASPSFLLYDD VAYFNMTLND INWDIVEEAK IVNFGSVILA RNPSRETVMK
160 170 180 190 200
VIKKIKGSSL IAFDVNLRLD LWRGQEEEMI KVLEESIKLA DIVKASEEEV
210 220 230 240 250
LYLENQGVEV KGSMLTAITL GPKGCRLIKN ETVVDVPSYN VNPLDTTGAG
260 270 280 290 300
DAFMAALLVG ILKLKGLDLL KLGKFANLVA ALSTQKRGAW STPRKDELLK
310
YKEAREVLAP
Length:310
Mass (Da):33,987
Last modified:August 1, 1998 - v1
Checksum:iF8CC41B678BE8611
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA Translation: BAA30566.1
PIRiF71020

Genome annotation databases

EnsemblBacteriaiBAA30566; BAA30566; BAA30566
KEGGipho:PH1459

Entry informationi

Entry nameiY1459_PYRHO
AccessioniPrimary (citable) accession number: O59128
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health