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O59080 (PDXS_PYRHO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pyridoxal biosynthesis lyase PdxS

EC=4.-.-.-
Gene names
Name:pdxS
Ordered Locus Names:PH1355
OrganismPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) [Complete proteome] [HAMAP]
Taxonomic identifier70601 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length335 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring By similarity. HAMAP-Rule MF_01824

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis. HAMAP-Rule MF_01824

Subunit structure

Forms a complex with PdxT By similarity. HAMAP-Rule MF_01824

Sequence similarities

Belongs to the PdxS/SNZ family.

Ontologies

Keywords
   LigandPyridoxal phosphate
   Molecular functionLyase
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological_processpyridoxal phosphate biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_function2-iminoacetate synthase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 335335Pyridoxal biosynthesis lyase PdxS HAMAP-Rule MF_01824
PRO_0000109445

Secondary structure

.................................................. 335
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
O59080 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: D5E178BB654E5196

FASTA33537,014
        10         20         30         40         50         60 
MDKLKIIMEK GTERLKRGFA KMVKGGVIMD VTNAEQARIA EEAGAVAVMA LHKVPADIRK 

        70         80         90        100        110        120 
AGGVARMAPV EKIQEIMDAV TIPVMAKCRI GHEAEARILE ALGVDMIDES EVLTPADPFF 

       130        140        150        160        170        180 
HIYKKKFTAP FVCGARNLGE AVRRIWEGAA MIRTKGEAGT GNIIEAVRHV RLVNENIRLI 

       190        200        210        220        230        240 
QRMTDEEIYG VAEKFAEPYL RLAFSVKEIS GLPKRVLENE PIYEGFTYRE IVEDIYKILL 

       250        260        270        280        290        300 
EIKKLGRLPV VNFAAGGVAT PADAALMMAM GMDGVFVGSG IFKSSNPPKM ARAIVEAVNH 

       310        320        330 
WDEPDVLAEI SREIGEPMRG QAIEELQVRM EERGI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000001 Genomic DNA. Translation: BAA30461.1.
PIRE71007.
RefSeqNP_143237.1. NC_000961.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4FIQX-ray2.70A/B/C/D/E/F1-335[»]
4FIRX-ray3.10A/B/C/D/E/F1-335[»]
ProteinModelPortalO59080.
SMRO59080. Positions 12-320.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActO59080. 1 interaction.
MINTMINT-1501312.
STRING70601.PH1355.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA30461; BAA30461; BAA30461.
GeneID1443680.
KEGGpho:PH1355.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0214.
HOGENOMHOG000227586.
KOK06215.
OMARIWEGAA.
ProtClustDBPRK04180.

Enzyme and pathway databases

BioCycPHOR70601:GJWR-1361-MONOMER.
UniPathwayUPA00245.

Family and domain databases

Gene3D3.20.20.70. 2 hits.
HAMAPMF_01824. PdxS.
InterProIPR013785. Aldolase_TIM.
IPR011060. RibuloseP-bd_barrel.
IPR001852. Snz1p/Sor1.
IPR008867. ThiG.
[Graphical view]
PfamPF01680. SOR_SNZ. 1 hit.
PF05690. ThiG. 1 hit.
[Graphical view]
PIRSFPIRSF029271. Pdx1. 1 hit.
SUPFAMSSF51366. SSF51366. 2 hits.
TIGRFAMsTIGR00343. TIGR00343. 1 hit.
PROSITEPS01235. PDXS_SNZ_1. 1 hit.
PS51129. PDXS_SNZ_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePDXS_PYRHO
AccessionPrimary (citable) accession number: O59080
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: August 1, 1998
Last modified: February 19, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

PATHWAY comments

Index of metabolic and biosynthesis pathways