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Protein

Putative adenylate kinase

Gene

PH1255

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.UniRule annotation

Catalytic activityi

ATP + AMP = 2 ADP.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei96ATPUniRule annotation1
Binding sitei100ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15ATPUniRule annotation6

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPHOR70601:G1G39-1215-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative adenylate kinaseUniRule annotation (EC:2.7.4.3UniRule annotation)
Short name:
AKUniRule annotation
Alternative name(s):
ATP-AMP transphosphorylaseUniRule annotation
Gene namesi
Ordered Locus Names:PH1255
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001539131 – 180Putative adenylate kinaseAdd BLAST180

Interactioni

Protein-protein interaction databases

STRINGi70601.PH1255

Structurei

3D structure databases

ProteinModelPortaliO58998
SMRiO58998
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni30 – 50NMPbindUniRule annotationAdd BLAST21
Regioni99 – 109LIDUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the adenylate kinase family. AK6 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01038 Archaea
COG1936 LUCA
HOGENOMiHOG000224471
KOiK18532
OMAiDNVQCEI
OrthoDBiPOG093Z0F8E

Family and domain databases

HAMAPiMF_00039 Adenylate_kinase_AK6, 1 hit
InterProiView protein in InterPro
IPR020618 Adenyl_kinase_AK6
IPR027417 P-loop_NTPase
PANTHERiPTHR12595:SF0 PTHR12595:SF0, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

O58998-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLIAITGTPG VGKTTVAKLL AKKLNYEYVS LKDFALEKGC GRRVNDEVEV
60 70 80 90 100
EIDELAYFIE RELKGKNAVL DGHLSHLMPV DLVVVLRAHP KLIGERLRER
110 120 130 140 150
GYDREKIGEN VEAELVDAVL IEAIEEHENV IEVDTTNKSP EDVVEEIVSL
160 170 180
INSGIKKRVG IVDWSEVYDE IIPYLRLGGE
Length:180
Mass (Da):20,178
Last modified:August 1, 1998 - v1
Checksum:iA82E4C0E9D7C3067
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA Translation: BAA30356.1
PIRiB71070
RefSeqiWP_010885344.1, NC_000961.1

Genome annotation databases

EnsemblBacteriaiBAA30356; BAA30356; BAA30356
GeneIDi1443579
KEGGipho:PH1255

Similar proteinsi

Entry informationi

Entry nameiKAD6_PYRHO
AccessioniPrimary (citable) accession number: O58998
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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