O58815 (O58815_PYRHO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
334aa long hypothetical aspartate-semialdehyde dehydrogenase EMBL BAA30187.1

Gene names

Ordered Locus Names:

PH1088

Organism

Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) [Complete proteome] [HAMAP]

Taxonomic identifier

70601 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	334 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aspartate-semialdehyde dehydrogenase family. RuleBase RU004041

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	isoleucine biosynthetic process Inferred from electronic annotation. Source: InterPro lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro methionine biosynthetic process Inferred from electronic annotation. Source: InterPro threonine biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	N-acetyl-gamma-glutamyl-phosphate reductase activity Inferred from electronic annotation. Source: InterPro NAD binding Inferred from electronic annotation. Source: InterPro NADP binding Inferred from electronic annotation. Source: InterPro aspartate-semialdehyde dehydrogenase activity Inferred from electronic annotation. Source: InterPro protein dimerization activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	142	1	Acyl-thioester intermediate By similarity PIRSR PIRSR000148-1

Sequences

	Sequence		Length	Mass (Da)
	O58815 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 29236D2EC49214F5	FASTA	334	37,120
	10 20 30 40 50 60 MKVAVLGATG VVGRTFVKLL ENHPWFKVEK LVASERSAGK RYGEIVEDSP EEFKDYTIIG 70 80 90 100 110 120 LKEFLEDPGV DLVFNALPAS ISKEVEEKLA QEIPVFTNAR SHRYDEDVPI LVPEVNSDHL 130 140 150 160 170 180 KLVEVQRKRR KWRGFIVTNP NCSTAILTVS LAPLRAFGIK KVRVATMQAI SGAGFSGLSA 190 200 210 220 230 240 YAIHDNVIPF INGEEWKIEN ESRKILGKFT GDKVEPAEIE VAAIATRVPV LHGHTEAVFV 250 260 270 280 290 300 ELEKFDIEEI REAFENFDPL RSLELPSYEK PIVYTEIPQP RLHRDRGKGL TVTVGRLQEI 310 320 330 SGGIKYVVLG HNLVRGAAGG SILNAELAYK LGII

References

[1]

"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3." Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T. , Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kikuchi H. DNA Res. 5:55-76(1998) [PubMed: 9679194] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3 and OT3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000001 Genomic DNA. Translation: BAA30187.1.
PIR	E71103.
RefSeq	NP_142995.1. NC_000961.1.
3D structure databases
ProteinModelPortal	O58815.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000001199; EBPYRP00000001199; EBPYRG00000001199.
GeneID	1443409.
GenomeReviews	Gene locus PH1088 in contig BA000001_GR.
KEGG	pho:PH1088.
NMPDR	fig|70601.1.peg.1062.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000023157.
HOGENOM	HBG518238.
OMA	GAGYNGV.
PhylomeDB	O58815.
ProtClustDB	PRK08664.
Enzyme and pathway databases
BioCyc	PHOR70601:PH1088-MONOMER.
Family and domain databases
InterPro	IPR005676. Asp_semi-ald_DH_pep-lack. IPR012080. Asp_semialdehyde_DH. IPR016040. NAD(P)-bd_dom. IPR000534. Semialdehyde_DH_NAD-bd. IPR012280. Semialdhyde_DH_dimer_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00133.
Pfam	PF01118. Semialdhyde_dh. 1 hit. PF02774. Semialdhyde_dhC. 1 hit. [Graphical view]
PIRSF	PIRSF000148. ASA_dh. 1 hit.
SMART	SM00859. Semialdhyde_dh. 1 hit. [Graphical view]
TIGRFAMs	TIGR00978. Asd_EA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

O58815_PYRHO

Accession

Primary (citable) accession number: O58815

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	August 1, 1998
Last modified:	December 14, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)