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O58778 (AOR_PYRHO) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Tungsten-containing aldehyde ferredoxin oxidoreductase
EC=1.2.7.5
Gene names
Name:aor
Ordered Locus Names:PH1019
OrganismPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) [Complete proteome] [HAMAP]
Taxonomic identifier70601 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length607 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

An aldehyde + H2O + 2 oxidized ferredoxin = a carboxylate + 2 H+ + 2 reduced ferredoxin.

Cofactor

Binds 1 4Fe-4S cluster per subunit By similarity.

Binds 1 tungstopterin cofactor per subunit By similarity.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the AOR/FOR family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 607607Tungsten-containing aldehyde ferredoxin oxidoreductase
PRO_0000064607

Sequences

Sequence LengthMass (Da)Tools
O58778 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 978039536AA58FBE

FASTA60767,537
        10         20         30         40         50         60 
MFGYWGKILR VNLSDGTIKE ETFNEEFAKK WLGTRGFGIY FLLKEMDPKI DPFSPENKLI 

        70         80         90        100        110        120 
FATGPLTGTS APTGGRYMVI TKSPLTGYIA MANSGGYFGA ELKFAGWDAI IVEGKADHPV 

       130        140        150        160        170        180 
YIYINDENVE IRDASKVWGK LVSETERMLK EEVGDKHVQI ASIGPAGENK VRFAAVMNNG 

       190        200        210        220        230        240 
HRAAGRGGVG AVMGSKNLKA IVVRGHKRVE VADKGKFMEV IREKIEKLRK DPVAGGGLPK 

       250        260        270        280        290        300 
YGTAVLVNII NEHGLYPTRN FQTGVFKYAY EQSGEAMAAK YLVRNKPCFA CPIGCGRVNY 

       310        320        330        340        350        360 
LPSIGETEGP EYESTWALGA NLGINDLASI IEANHFADEY GMDTISLGGT LATAMELYER 

       370        380        390        400        410        420 
GLIKQEDIGG ENEPPFRFGN TEVLHYWIHK IAKREGFGDI LAEGGYRLAE KFNGLEYFMG 

       430        440        450        460        470        480 
VKKQELPAYD PRGAEGHGLG YATNNRGGCH IKQYMISPEI LGYPYKMDPH DISDEKVKMV 

       490        500        510        520        530        540 
ILFQDLTAVI DAAGLCIFTT FGLGADDYTD MLNAALGWDF STDDYLKIGE RIWNAERLFN 

       550        560        570        580        590        600 
LKAGLDPLKE DTLPKRFLEE PMPEGPNKGH VVRLKEMLPR YYKLRGWTED GRIPEEKLKE 


LGLEEFM

« Hide

References

[1]"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3."
Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T. expand/collapse author list , Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.
DNA Res. 5:55-76(1998) [PubMed: 9679194] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000001 Genomic DNA. Translation: BAA30116.1.
PIRF71094.
RefSeqNP_142931.1. NC_000961.1.

3D structure databases

ProteinModelPortalO58778.
SMRO58778. Positions 1-606.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBPYRT00000002042; EBPYRP00000002042; EBPYRG00000002042.
GeneID1443341.
GenomeReviewsGene locus PH1019 in contig BA000001_GR.
KEGGpho:PH1019.
NMPDRfig|70601.1.peg.994.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000022332.
HOGENOMHBG496827.
OMAPAKHIWG.
PhylomeDBO58778.
ProtClustDBCLSK253319.

Enzyme and pathway databases

BioCycPHOR70601:PH1019-MONOMER.

Family and domain databases

InterProIPR013985. Ald_Fedxn_OxRdtase_3.
IPR013983. Ald_Fedxn_OxRdtase_N.
IPR001203. OxRdtase_Ald_Fedxn_C.
[Graphical view]
Gene3DG3DSA:1.10.599.10. Oxred_Ald_Fedxn_3. 1 hit.
G3DSA:3.60.9.10. Oxred_Ald_Fedxn_N. 1 hit.
KOK03738.
PfamPF01314. AFOR_C. 1 hit.
PF02730. AFOR_N. 1 hit.
[Graphical view]
SMARTSM00790. AFOR_N. 1 hit.
[Graphical view]
SUPFAMSSF48310. Oxred_Ald_Fedxn_C. 1 hit.
SSF56228. Oxred_Ald_Fedxn_N. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAOR_PYRHO
AccessionPrimary (citable) accession number: O58778
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: January 25, 2012
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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