ID   O58740_PYRHO            Unreviewed;       165 AA.
AC   O58740;
DT   01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT   01-AUG-1998, sequence version 1.
DT   27-MAR-2024, entry version 125.
DE   RecName: Full=CYTH domain-containing protein {ECO:0000259|PROSITE:PS51707};
GN   OrderedLocusNames=PH1012 {ECO:0000313|EMBL:BAA30109.1};
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601 {ECO:0000313|EMBL:BAA30109.1, ECO:0000313|Proteomes:UP000000752};
RN   [1] {ECO:0000313|EMBL:BAA30109.1, ECO:0000313|Proteomes:UP000000752}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3
RC   {ECO:0000313|Proteomes:UP000000752};
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Nakamura Y.,
RA   Robb T.F., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
RN   [2] {ECO:0007829|PDB:2DC4}
RP   X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS).
RA   Bagautdinov B., Kunishima N.;
RT   "Crystal structure of PH1012 protein from Pyrococcus Horikoshii OT3.";
RL   Submitted (DEC-2005) to the PDB data bank.
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DR   EMBL; BA000001; BAA30109.1; -; Genomic_DNA.
DR   PIR; G71093; G71093.
DR   RefSeq; WP_010885098.1; NC_000961.1.
DR   PDB; 2DC4; X-ray; 1.65 A; A/B=1-165.
DR   PDBsum; 2DC4; -.
DR   AlphaFoldDB; O58740; -.
DR   SMR; O58740; -.
DR   STRING; 70601.gene:9377969; -.
DR   EnsemblBacteria; BAA30109; BAA30109; BAA30109.
DR   GeneID; 1443333; -.
DR   KEGG; pho:PH1012; -.
DR   eggNOG; arCOG01723; Archaea.
DR   OrthoDB; 46040at2157; -.
DR   EvolutionaryTrace; O58740; -.
DR   Proteomes; UP000000752; Chromosome.
DR   CDD; cd07890; CYTH-like_AC_IV-like; 1.
DR   Gene3D; 2.40.320.10; Hypothetical Protein Pfu-838710-001; 1.
DR   InterPro; IPR008173; Adenylyl_cyclase_CyaB.
DR   InterPro; IPR033469; CYTH-like_dom_sf.
DR   InterPro; IPR023577; CYTH_domain.
DR   NCBIfam; TIGR00318; cyaB; 1.
DR   PANTHER; PTHR21028:SF2; CYTH DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR21028; SI:CH211-156B7.4; 1.
DR   Pfam; PF01928; CYTH; 1.
DR   SMART; SM01118; CYTH; 1.
DR   SUPFAM; SSF55154; CYTH-like phosphatases; 1.
DR   PROSITE; PS51707; CYTH; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:2DC4}.
FT   DOMAIN          1..165
FT                   /note="CYTH"
FT                   /evidence="ECO:0000259|PROSITE:PS51707"
SQ   SEQUENCE   165 AA;  19580 MW;  B0D3A63365F8BD8E CRC64;
     MEIEVKFRVN FEDIKRKIEG LGAKFFGIEE QEDVYFELPS PKLLRVRKIN NTGKSYITYK
     EILDKRNEEF YELEFEVQDP EGAIELFKRL GFKVQGVVKK RRWIYKLNNV TFELNRVEKA
     GDFLDIEVIT SNPEEGKKII WDVARRLGLK EEDVEPKLYI ELING
//